Silvana Konermann
Silvana Konermann
Stanford University, Howard Hughes Medical Institute
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Cited by
Cited by
DNA targeting specificity of RNA-guided Cas9 nucleases
PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ...
Nature biotechnology 31 (9), 827-832, 2013
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ...
Cell 154 (6), 1380-1389, 2013
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
Crystal structure of Cas9 in complex with guide RNA and target DNA
H Nishimasu, FA Ran, PD Hsu, S Konermann, SI Shehata, N Dohmae, ...
Cell 156 (5), 935-949, 2014
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ...
Science 353 (6299), aaf5573, 2016
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ...
Molecular cell 60 (3), 385-397, 2015
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
X Wu, DA Scott, AJ Kriz, AC Chiu, PD Hsu, DB Dadon, AW Cheng, ...
Nature biotechnology 32 (7), 670-676, 2014
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ...
Nature protocols 12 (4), 828-863, 2017
Optical control of mammalian endogenous transcription and epigenetic states
S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ...
Nature 500 (7463), 472-476, 2013
Transcriptome engineering with RNA-targeting type VI-D CRISPR effectors
S Konermann, P Lotfy, NJ Brideau, J Oki, MN Shokhirev, PD Hsu
Cell 173 (3), 665-676. e14, 2018
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ...
Nature 548 (7667), 343-346, 2017
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ...
Nature biotechnology 33 (11), 1159-1161, 2015
Recombinant virus and preparations thereof
F Zhang, MD Brigham, L Cong, S Konermann
US Patent 11,332,719, 2022
Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d
C Zhang, S Konermann, NJ Brideau, P Lotfy, X Wu, SJ Novick, ...
Cell 175 (1), 212-223. e17, 2018
Inducible dna binding proteins and genome perturbation tools and applications thereof
F Zhang, M Brigham, L Cong, S Konermann, NE Sanjana
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
SB Biering, SA Sarnik, E Wang, JR Zengel, SR Leist, A Schäfer, ...
Nature genetics 54 (8), 1078-1089, 2022
CRISPR enzymes and systems
K Severinov, F Zhang, YI Wolf, S Shmakov, E Semenova, L Minakhin, ...
US Patent 11,060,115, 2021
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
S Konermann, A Trevino, M Brigham, RAN Fei, P Hsu, C Lin, O Nureki, ...
US Patent 10,550,372, 2020
Functional screening with optimized functional CRISPR-Cas systems
F Zhang, S Konermann, MD Brigham, A Trevino
US Patent 11,001,829, 2021
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