A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity I Weisberg, P Tran, B Christensen, S Sibani, R Rozen Molecular genetics and metabolism 64 (3), 169-172, 1998 | 1782 | 1998 |
The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia BD Guenther, CA Sheppard, P Tran, R Rozen, RG Matthews, ML Ludwig Nature structural biology 6 (4), 359-365, 1999 | 562 | 1999 |
Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR) P Goyette, A Pai, R Milos, P Frosst, P Tran, Z Chen, M Chan, R Rozen Mammalian Genome 9, 652-656, 1998 | 549 | 1998 |
Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects B Christensen, L Arbour, P Tran, D Leclerc, N Sabbaghian, R Platt, ... American journal of medical genetics 84 (2), 151-157, 1999 | 410 | 1999 |
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia PV Tran, CJ Haycraft, TY Besschetnova, A Turbe-Doan, RW Stottmann, ... Nature genetics 40 (4), 403-410, 2008 | 373 | 2008 |
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse JL Moran, AD Bolton, PV Tran, A Brown, ND Dwyer, DK Manning, ... Genome research 16 (3), 436-440, 2006 | 110 | 2006 |
Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms P Tran, D Leclerc, M Chan, A Pai, F Hiou-Tim, Q Wu, P Goyette, C Artigas, ... Mammalian Genome 13 (9), 483-492, 2002 | 104 | 2002 |
Temporomandibular joint formation requires two distinct hedgehog-dependent steps P Purcell, BW Joo, JK Hu, PV Tran, ML Calicchio, DJ O'Connell, RL Maas, ... Proceedings of the National Academy of Sciences 106 (43), 18297-18302, 2009 | 100 | 2009 |
Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain RW Stottmann, PV Tran, A Turbe-Doan, DR Beier Developmental biology 335 (1), 166-178, 2009 | 96 | 2009 |
Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models PV Tran, GC Talbott, A Turbe-Doan, DT Jacobs, MP Schonfeld, LM Silva, ... Journal of the American Society of Nephrology 25 (10), 2201-2212, 2014 | 89 | 2014 |
Application of WRF/Chem-MADRID and WRF/Polyphemus in Europe–Part 2: Evaluation of chemical concentrations and sensitivity simulations Y Zhang, K Sartelet, S Zhu, W Wang, SY Wu, X Zhang, K Wang, P Tran, ... Atmospheric Chemistry and Physics 13 (14), 6845-6875, 2013 | 55 | 2013 |
Cholesterol Metabolism Is Required for Intracellular Hedgehog Signal Transduction In Vivo RW Stottmann, A Turbe-Doan, P Tran, LE Kratz, JL Moran, RI Kelley, ... PLoS genetics 7 (9), e1002224, 2011 | 53 | 2011 |
Intraflagellar transport proteins as regulators of primary cilia length W Wang, BM Jack, HH Wang, MA Kavanaugh, RL Maser, PV Tran Frontiers in cell and developmental biology 9, 661350, 2021 | 49 | 2021 |
Aberrant regulation of Notch3 signaling pathway in polycystic kidney disease J Idowu, T Home, N Patel, B Magenheimer, PV Tran, RL Maser, CJ Ward, ... Scientific reports 8 (1), 3340, 2018 | 44 | 2018 |
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells LM Silva, DT Jacobs, BA Allard, TA Fields, M Sharma, DP Wallace, ... Scientific reports 8 (1), 4985, 2018 | 39 | 2018 |
Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development J Snedeker, EN Schock, JN Struve, CF Chang, M Cionni, PV Tran, ... PloS one 12 (3), e0173258, 2017 | 31 | 2017 |
Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis? PV Tran, M Sharma, X Li, JP Calvet Birth Defects Research Part C: Embryo Today: Reviews 102 (2), 159-173, 2014 | 31 | 2014 |
Primary cilia in cystic kidney disease P Avasthi, RL Maser, PV Tran Kidney Development and Disease, 281-321, 2017 | 28 | 2017 |
Ciclopirox olamine induces ferritinophagy and reduces cyst burden in polycystic kidney disease PS Radadiya, MM Thornton, RV Puri, S Yerrathota, J Dinh-Phan, ... JCI insight 6 (8), 2021 | 25 | 2021 |
Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-κB sensitivity L Pickell, P Tran, D Leclerc, J Hiscott, R Rozen Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1731 (2 …, 2005 | 24 | 2005 |