Johan Auwerx
Johan Auwerx
Professor at the EPFL
Verified email at - Homepage
Cited by
Cited by
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, C Lerin, F Daussin, ...
Cell 127 (6), 1109-1122, 2006
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L Noriega, JC Milne, ...
Nature 458 (7241), 1056-1060, 2009
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
M Watanabe, SM Houten, C Mataki, MA Christoffolete, BW Kim, H Sato, ...
Nature 439 (7075), 484-489, 2006
Mechanism of action of fibrates on lipid and lipoprotein metabolism
B Staels, J Dallongeville, J Auwerx, K Schoonjans, E Leitersdorf, ...
Circulation 98 (19), 2088-2093, 1998
Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity
SH Um, F Frigerio, M Watanabe, F Picard, M Joaquin, M Sticker, ...
Nature 431 (7005), 200-205, 2004
A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
SS Deeb, L Fajas, M Nemoto, J Pihlajamäki, L Mykkänen, J Kuusisto, ...
Nature genetics 20 (3), 284-287, 1998
Sirtuins as regulators of metabolism and healthspan
RH Houtkooper, E Pirinen, J Auwerx
Nature reviews Molecular cell biology 13 (4), 225-238, 2012
The organization, promoter analysis, and expression of the human PPARγ gene
L Fajas, D Auboeuf, E Raspé, K Schoonjans, AM Lefebvre, R Saladin, ...
Journal of Biological Chemistry 272 (30), 18779-18789, 1997
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
TT Lu, M Makishima, JJ Repa, K Schoonjans, TA Kerr, J Auwerx, ...
Molecular cell 6 (3), 507-515, 2000
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
K Schoonjans, B Staels, J Auwerx
Journal of lipid research 37 (5), 907-925, 1996
TGR5-mediated bile acid sensing controls glucose homeostasis
C Thomas, A Gioiello, L Noriega, A Strehle, J Oury, G Rizzo, ...
Cell metabolism 10 (3), 167-177, 2009
Transient increase in obese gene expression after food intake or insulin administration
R Saladin, P De Vos, M Guerre-Millot, A Leturque, J Girard, B Staels, ...
Nature 377 (6549), 527-528, 1995
PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
K Schoonjans, J Peinado‐Onsurbe, AM Lefebvre, RA Heyman, M Briggs, ...
The EMBO journal 15 (19), 5336-5348, 1996
The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation
K Schoonjans, B Staels, J Auwerx
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1302 (2), 93-109, 1996
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
C Cantó, J Auwerx
Current opinion in lipidology 20 (2), 98, 2009
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
S Timmers, E Konings, L Bilet, RH Houtkooper, T van de Weijer, ...
Cell metabolism 14 (5), 612-622, 2011
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
M Watanabe, SM Houten, L Wang, A Moschetta, DJ Mangelsdorf, ...
The Journal of clinical investigation 113 (10), 1408-1418, 2004
Targeting bile-acid signalling for metabolic diseases
C Thomas, R Pellicciari, M Pruzanski, J Auwerx, K Schoonjans
Nature reviews Drug discovery 7 (8), 678-693, 2008
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors
L Michalik, J Auwerx, JP Berger, VK Chatterjee, CK Glass, FJ Gonzalez, ...
Pharmacological reviews 58 (4), 726-741, 2006
A unified nomenclature system for the nuclear receptor superfamily
J Auwerx, E Baulieu, M Beato, M Becker-Andre, PH Burbach, G Camerino, ...
Cell 97 (2), 161-163, 1999
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