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Sebastian Rühl
Sebastian Rühl
Senior Researcher at T3 Pharmaceuticals AG
Verified email at stjude.org
Title
Cited by
Cited by
Year
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ...
The EMBO journal 35 (16), 1766-1778, 2016
9822016
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
S Rühl, K Shkarina, B Demarco, R Heilig, JC Santos, P Broz
Science 362 (6417), 956-960, 2018
5332018
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K+ efflux
S Rühl, P Broz
European journal of immunology 45 (10), 2927-2936, 2015
4872015
ASC filament formation serves as a signal amplification mechanism for inflammasomes
MS Dick, L Sborgi, S Rühl, S Hiller, P Broz
Nature communications 7 (1), 1-13, 2016
3492016
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
E Meunier, P Wallet, RF Dreier, S Costanzo, L Anton, S Rühl, ...
Nature immunology 16 (5), 476-484, 2015
3472015
Caspase-8-dependent inflammatory responses are controlled by its adaptor, FADD, and necroptosis
B Tummers, L Mari, CS Guy, BL Heckmann, DA Rodriguez, S Rühl, ...
Immunity 52 (6), 994-1006. e8, 2020
832020
Regulation of lytic and non-lytic functions of gasdermin pores
S Rühl, P Broz
Journal of molecular biology 434 (4), 167246, 2022
412022
Disruption of coronin 1 signaling in T cells promotes allograft tolerance while maintaining anti-pathogen immunity
R Jayachandran, A Gumienny, B Bolinger, S Ruehl, MJ Lang, G Fucile, ...
Immunity 50 (1), 152-165. e8, 2019
272019
The gasdermin-D pore: executor of pyroptotic cell death
S Rühl, P Broz
Oncotarget 7 (36), 57481, 2016
262016
Non-lethal outcomes of engaging regulated cell death pathways in cancer
H Kalkavan, S Rühl, JJP Shaw, DR Green
Nature Cancer 4 (6), 795-806, 2023
142023
Corrigendum: ASC filament formation serves as a signal amplification mechanism for inflammasomes
MS Dick, L Sborgi, S Rühl, S Hiller, P Broz
Nature Communications 8, 2017
132017
Activation of the cAMP/protein kinase A signalling pathway by coronin 1 is regulated by cyclin‐dependent kinase 5 activity
X Liu, S BoseDasgupta, R Jayachandran, V Studer, S Rühl, M Stiess, ...
FEBS letters 590 (2), 279-287, 2016
102016
Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis
G Quarato, L Mari, NJ Barrows, M Yang, S Ruehl, MJ Chen, CS Guy, ...
Science Advances 9 (21), eadg8156, 2023
62023
Anti-apoptotic BH3-only proteins inhibit Bak-dependent apoptosis
S Ruehl, CS Guy, Z Li, M Yang, T Moldoveanu, DR Green
BioRxiv, 2022.07. 24.499430, 2022
32022
Effector mechanisms of non-canonical inflammasome activation
S Rühl
University_of_Basel, 2018
2018
Investigating the Role of Coronin 1 in Beta Adrenergic Receptor Signaling and T Cell Homeostasis
S Rühl
Biozentrum, Universität Basel, 2013
2013
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