| Structural basis for regulation of human acetyl-CoA carboxylase M Hunkeler, A Hagmann, E Stuttfeld, M Chami, Y Guri, H Stahlberg, ... Nature 558, 470–474, 2018 | 170 | 2018 |
| Small-molecule-induced polymerization triggers degradation of BCL6 M Słabicki, H Yoon, J Koeppel, L Nitsch, SS Roy Burman, C Di Genua, ... Nature 588 (7836), 164-168, 2020 | 153 | 2020 |
| The mycobacterial Mpa–proteasome unfolds and degrades pupylated substrates by engaging Pup's N‐terminus F Striebel, M Hunkeler, H Summer, E Weber‐Ban The EMBO journal 29 (7), 1262-1271, 2010 | 134 | 2010 |
| The dynamic organization of fungal acetyl-CoA carboxylase M Hunkeler, E Stuttfeld, A Hagmann, S Imseng, T Maier Nature communications 7 (1), 11196, 2016 | 54 | 2016 |
| Dimeric structure of the bacterial extracellular foldase PrsA RP Jakob, JR Koch, BM Burmann, PAM Schmidpeter, M Hunkeler, ... Journal of Biological Chemistry 290 (6), 3278-3292, 2015 | 45 | 2015 |
| Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition M Hunkeler, CY Jin, MW Ma, JK Monda, D Overwijn, EJ Bennett, ... Molecular cell 81 (17), 3468-3480. e7, 2021 | 33* | 2021 |
| Structural basis of regulated m7G tRNA modification by METTL1–WDR4 J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ... Nature 613 (7943), 391-397, 2023 | 30 | 2023 |
| Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, R Lumpkin, ... BioRxiv, 2023 | 22 | 2023 |
| Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases M Hunkeler, CY Jin, ES Fischer Science 379 (6637), 1105-1111, 2023 | 9 | 2023 |
| HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways JK Monda, X Ge, M Hunkeler, KA Donovan, MW Ma, CY Jin, M Leonard, ... Cell reports 42 (5), 2023 | 5 | 2023 |
| Hybrid structure of a dynamic single-chain carboxylase from Deinococcus radiodurans A Hagmann, M Hunkeler, E Stuttfeld, T Maier Structure 24 (8), 1227-1236, 2016 | 4 | 2016 |
| HUWE1 amplifies ubiquitin modifications to broadly stimulate clearance of proteins and aggregates M Zhou, R Fang, L Colson, K Donovan, M Hunkeler, S Chen, Y Song, ... BioRxiv, 2023.05. 30.542866, 2023 | 2 | 2023 |
| Continuous evolution of compact protein degradation tags regulated by selective molecular glues JAM Mercer, SJ DeCarlo, SS Roy Burman, V Sreekanth, AT Nelson, ... Science 383 (6688), eadk4422, 2024 | 1 | 2024 |
| Dynamic architecture of multi-domain carboxylases M Hunkeler University_of_Basel, 2015 | 1 | 2015 |
| Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF S Radko-Juettner, H Yue, JA Myers, RD Carter, AN Robertson, P Mittal, ... Nature 628 (8007), 442-449, 2024 | | 2024 |
Eric S FischerProfessor of Biological Chemistry and Molecular Pharmacology, Harvard Medical SchoolVerified email at crystal.harvard.edu
