Follow
Matthieu Schapira
Title
Cited by
Cited by
Year
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding, I Novoa, Y Zhang, H Zeng, R Wek, M Schapira, D Ron
Molecular cell 6 (5), 1099-1108, 2000
36902000
Epigenetic protein families: a new frontier for drug discovery
CH Arrowsmith, C Bountra, PV Fish, K Lee, M Schapira
Nature reviews Drug discovery 11 (5), 384-400, 2012
15572012
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
8282015
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
DB Yap, J Chu, T Berg, M Schapira, SWG Cheng, A Moradian, RD Morin, ...
Blood, The Journal of the American Society of Hematology 117 (8), 2451-2459, 2011
7052011
Targeted protein degradation: expanding the toolbox
M Schapira, MF Calabrese, AN Bullock, CM Crews
Nature reviews Drug discovery 18 (12), 949-963, 2019
5832019
A systematic analysis of atomic protein–ligand interactions in the PDB
RF de Freitas, M Schapira
Medchemcomm 8 (10), 1970-1981, 2017
3692017
Recognition and specificity determinants of the human cbx chromodomains
L Kaustov, H Ouyang, M Amaya, A Lemak, N Nady, S Duan, GA Wasney, ...
Journal of Biological Chemistry 286 (1), 521-529, 2011
3442011
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity
A Schuetz, J Min, A Allali-Hassani, M Schapira, M Shuen, P Loppnau, ...
Journal of Biological Chemistry 283 (17), 11355-11363, 2008
3222008
Structural biology of human H3K9 methyltransferases
H Wu, J Min, VV Lunin, T Antoshenko, L Dombrovski, H Zeng, ...
PloS one 5 (1), e8570, 2010
3062010
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors
W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ...
Nature communications 3 (1), 1288, 2012
2962012
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ...
Nature chemical biology 11 (8), 571-578, 2015
2772015
Structural basis for the discriminative recognition of N6-methyladenosine RNA by the human YT521-B homology domain family of proteins
C Xu, K Liu, H Ahmed, P Loppnau, M Schapira, J Min
Journal of Biological Chemistry 290 (41), 24902-24913, 2015
2652015
WD40 repeat domain proteins: a novel target class?
M Schapira, M Tyers, M Torrent, CH Arrowsmith
Nature reviews Drug discovery 16 (11), 773-786, 2017
2382017
A potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases
MS Eram, Y Shen, MM Szewczyk, H Wu, G Senisterra, F Li, KV Butler, ...
ACS chemical biology 11 (3), 772-781, 2016
2282016
Nuclear hormone receptor targeted virtual screening
M Schapira, R Abagyan, M Totrov
Journal of medicinal chemistry 46 (14), 3045-3059, 2003
2202003
Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking
M Schapira, BM Raaka, S Das, L Fan, M Totrov, Z Zhou, SR Wilson, ...
Proceedings of the National Academy of Sciences 100 (12), 7354-7359, 2003
2202003
Prediction of the binding energy for small molecules, peptides and proteins
M Schapira, M Totrov, R Abagyan
Journal of Molecular Recognition 12 (3), 177-190, 1999
2201999
Protein arginine methylation: from enigmatic functions to therapeutic targeting
Q Wu, M Schapira, CH Arrowsmith, D Barsyte-Lovejoy
Nature reviews Drug discovery 20 (7), 509-530, 2021
2192021
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells
D Barsyte-Lovejoy, F Li, MJ Oudhoff, JH Tatlock, A Dong, H Zeng, H Wu, ...
Proceedings of the National Academy of Sciences 111 (35), 12853-12858, 2014
1812014
Rational discovery of novel nuclear hormone receptor antagonists
M Schapira, BM Raaka, HH Samuels, R Abagyan
Proceedings of the National Academy of Sciences 97 (3), 1008-1013, 2000
1742000
The system can't perform the operation now. Try again later.
Articles 1–20