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Nicolas Widmer
Nicolas Widmer
Lausanne University Hospital and University of Lausanne
Adresse e-mail validée de unil.ch - Page d'accueil
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Towards a new combination therapy for tuberculosis with next generation benzothiazinones
V Makarov, B Lechartier, M Zhang, J Neres, AM van der Sar, SA Raadsen, ...
EMBO molecular medicine 6 (3), 372-383, 2014
3942014
Review of therapeutic drug monitoring of anticancer drugs part two–targeted therapies
N Widmer, C Bardin, E Chatelut, A Paci, J Beijnen, D Levêque, G Veal, ...
European journal of cancer 50 (12), 2020-2036, 2014
3352014
Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib
A Haouala, N Widmer, MA Duchosal, M Montemurro, T Buclin, ...
Blood, The Journal of the American Society of Hematology 117 (8), e75-e87, 2011
2912011
Review of therapeutic drug monitoring of anticancer drugs part 1–cytotoxics
A Paci, G Veal, C Bardin, D Levêque, N Widmer, J Beijnen, A Astier, ...
European journal of cancer 50 (12), 2010-2019, 2014
2782014
Therapeutic drug monitoring of the new targeted anticancer agents imatinib, nilotinib, dasatinib, sunitinib, sorafenib and lapatinib by LC tandem mass spectrometry
A Haouala, B Zanolari, B Rochat, M Montemurro, K Zaman, MA Duchosal, ...
Journal of Chromatography B 877 (22), 1982-1996, 2009
2362009
Population pharmacokinetics of imatinib and the role of α1‐acid glycoprotein
N Widmer, LA Decosterd, C Csajka, S Leyvraz, MA Duchosal, A Rosselet, ...
British journal of clinical pharmacology 62 (1), 97-112, 2006
2162006
Benchmarking therapeutic drug monitoring software: a review of available computer tools
A Fuchs, C Csajka, Y Thoma, T Buclin, N Widmer
Clinical pharmacokinetics 52, 9-22, 2013
1922013
Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole …
LA Decosterd, B Rochat, B Pesse, T Mercier, F Tissot, N Widmer, J Bille, ...
Antimicrobial agents and chemotherapy 54 (12), 5303-5315, 2010
1522010
Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability
N Widmer, LA Decosterd, S Leyvraz, MA Duchosal, A Rosselet, ...
British journal of cancer 98 (10), 1633-1640, 2008
1352008
Therapeutic drug monitoring in cancer–are we missing a trick?
C Bardin, G Veal, A Paci, E Chatelut, A Astier, D Levêque, N Widmer, ...
European journal of cancer 50 (12), 2005-2009, 2014
1322014
Higher CNS Penetration-Effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid
A Cusini, PL Vernazza, S Yerly, LA Decosterd, B Ledergerber, CA Fux, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2012
1242012
Functional consequence of MDR1 expression on imatinib intracellular concentrations
N Widmer, S Colombo, T Buclin, LA Decosterd
Blood 102 (3), 1142-1142, 2003
1152003
Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term
M Neef, M Ledermann, H Saegesser, V Schneider, N Widmer, ...
Journal of hepatology 44 (1), 167-175, 2006
1072006
Correlations between imatinib pharmacokinetics, pharmacodynamics, adherence, and clinical response in advanced metastatic gastrointestinal stromal tumor (GIST): an emerging …
M von Mehren, N Widmer
Cancer treatment reviews 37 (4), 291-299, 2011
912011
Determination of imatinib (Gleevec®) in human plasma by solid-phase extraction–liquid chromatography–ultraviolet absorbance detection
N Widmer, A Beguin, B Rochat, T Buclin, T Kovacsovics, MA Duchosal, ...
Journal of Chromatography B 803 (2), 285-292, 2004
862004
The steps to therapeutic drug monitoring: a structured approach illustrated with imatinib
T Buclin, Y Thoma, N Widmer, C Csajka
Frontiers in pharmacology 11, 512469, 2020
792020
Clinical usefulness of therapeutic concentration monitoring for imatinib dosage individualization: results from a randomized controlled trial
V Gotta, N Widmer, LA Decosterd, Y Chalandon, D Heim, M Gregor, ...
Cancer chemotherapy and pharmacology 74, 1307-1319, 2014
792014
Population pharmacokinetic study of gentamicin in a large cohort of premature and term neonates
A Fuchs, M Guidi, E Giannoni, D Werner, T Buclin, N Widmer, C Csajka
British journal of clinical pharmacology 78 (5), 1090-1101, 2014
682014
Therapeutic drug monitoring of imatinib: Bayesian and alternative methods to predict trough levels
V Gotta, N Widmer, M Montemurro, S Leyvraz, A Haouala, LA Decosterd, ...
Clinical pharmacokinetics 51, 187-201, 2012
642012
Oseltamivir in seasonal, avian H5N1 and pandemic 2009 A/H1N1 influenza: pharmacokinetic and pharmacodynamic characteristics
N Widmer, P Meylan, A Ivanyuk, M Aouri, LA Decosterd, T Buclin
Clinical pharmacokinetics 49, 741-765, 2010
642010
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