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Simon Heales
Simon Heales
Unknown affiliation
Verified email at ucl.ac.uk
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Cited by
Cited by
Year
Association between mitochondrial dysfunction and severity and outcome of septic shock
D Brealey, M Brand, I Hargreaves, S Heales, J Land, R Smolenski, ...
The Lancet 360 (9328), 219-223, 2002
17192002
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
PJ Pollard, JJ Briere, NA Alam, J Barwell, E Barclay, NC Wortham, T Hunt, ...
Human molecular genetics 14 (15), 2231-2239, 2005
10172005
Nitric oxide‐mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases
JP Bolaños, A Almeida, V Stewart, S Peuchen, JM Land, JB Clark, ...
Journal of neurochemistry 68 (6), 2227-2240, 1997
6931997
Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture
JP Bolaños, SJR Heales, JM Land, JB Clark
Journal of neurochemistry 64 (5), 1965-1972, 1995
6101995
Nitric oxide, mitochondria and neurological disease
SJR Heales, JP Bolaños, VC Stewart, PS Brookes, JM Land, JB Clark
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1410 (2), 215-228, 1999
5891999
Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains
ME Gegg, D Burke, SJR Heales, JM Cooper, J Hardy, NW Wood, ...
Annals of neurology 72 (3), 455-463, 2012
5782012
Nitric oxide‐mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
JP Bolanos, S Peuchen, SJR Heales, JM Land, JB Clark
Journal of neurochemistry 63 (3), 910-916, 1994
5101994
Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice
LM Martins, A Morrison, K Klupsch, V Fedele, N Moisoi, P Teismann, ...
Molecular and cellular biology, 2004
4972004
PINK1 protein in normal human brain and Parkinson's disease
S Gandhi, MMK Muqit, L Stanyer, DG Healy, PM Abou-Sleiman, ...
Brain 129 (7), 1720-1731, 2006
4162006
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
A Wood-Kaczmar, S Gandhi, Z Yao, ASY Abramov, EA Miljan, G Keen, ...
PloS one 3 (6), e2455, 2008
3932008
Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders
K Augustin, A Khabbush, S Williams, S Eaton, M Orford, JH Cross, ...
The Lancet Neurology 17 (1), 84-93, 2018
3892018
The monoamine neurotransmitter disorders: an expanding range of neurological syndromes
MA Kurian, P Gissen, M Smith, SJR Heales, PT Clayton
The Lancet Neurology 10 (8), 721-733, 2011
3702011
Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5′-phosphate oxidase
PB Mills, RAH Surtees, MP Champion, CE Beesley, N Dalton, ...
Human molecular genetics 14 (8), 1077-1086, 2005
3522005
Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione
JP Bolaños, SJR Heales, S Peuchen, JE Barker, JM Land, JB Clark
Free Radical Biology and Medicine 21 (7), 995-1001, 1996
3381996
Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function
MJ Jackson, S Papa, J Bolaños, R Bruckdorfer, H Carlsen, RM Elliott, ...
Molecular aspects of medicine 23 (1-3), 209-285, 2002
2912002
Monoamine neurotransmitter disorders—clinical advances and future perspectives
J Ng, A Papandreou, SJ Heales, MA Kurian
Nature Reviews Neurology 11 (10), 567-584, 2015
2562015
Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration
GC Brown, JP Bolaños, SJR Heales, JB Clark
Neuroscience letters 193 (3), 201-204, 1995
2551995
Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia
MA Kurian, J Zhen, SY Cheng, Y Li, SR Mordekar, P Jardine, NV Morgan, ...
The Journal of clinical investigation 119 (6), 1595-1603, 2009
2422009
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice
S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ...
Free Radical Biology and Medicine 48 (1), 161-172, 2010
2392010
Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene
B Lüdecke, PM Knappskog, PT Clayton, RAH Surtees, JD Clelland, ...
Human molecular genetics 5 (7), 1023-1028, 1996
2381996
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