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David Teplow
David Teplow
Professor of Neurology, UCLA
No verified email - Homepage
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Cited by
Year
β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
R Vassar, BD Bennett, S Babu-Khan, S Kahn, EA Mendiaz, P Denis, ...
science 286 (5440), 735-741, 1999
52101999
Amyloid β-peptide is produced by cultured cells during normal metabolism
C Haass, MG Schlossmacher, AY Hung, C Vigo-Pelfrey, A Mellon, ...
Nature 359 (6393), 322-325, 1992
26991992
A cellular gene encodes scrapie PrP 27-30 protein
B Oesch, D Westaway, M Wälchli, MP McKinley, SBH Kent, R Aebersold, ...
Cell 40 (4), 735-746, 1985
20461985
Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways
G Bitan, MD Kirkitadze, A Lomakin, SS Vollers, GB Benedek, DB Teplow
Proceedings of the National Academy of Sciences 100 (1), 330-335, 2003
16212003
The'Arctic'APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
C Nilsberth, A Westlind-Danielsson, CB Eckman, MM Condron, ...
Nature neuroscience 4 (9), 887-893, 2001
15092001
Amyloid β-protein fibrillogenesis: structure and biological activity of protofibrillar intermediates
DM Walsh, DM Hartley, Y Kusumoto, Y Fezoui, MM Condron, A Lomakin, ...
Journal of Biological Chemistry 274 (36), 25945-25952, 1999
14221999
Amyloid β-protein fibrillogenesis: detection of a protofibrillar intermediate
DM Walsh, A Lomakin, GB Benedek, MM Condron, DB Teplow
Journal of Biological Chemistry 272 (35), 22364-22372, 1997
13801997
Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
DM Hartley, DM Walsh, PY Chianping, T Diehl, S Vasquez, PM Vassilev, ...
Journal of Neuroscience 19 (20), 8876-8884, 1999
12351999
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
SL Bernstein, NF Dupuis, ND Lazo, T Wyttenbach, MM Condron, G Bitan, ...
Nature chemistry 1 (4), 326-331, 2009
10302009
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.
A Lomakin, DS Chung, GB Benedek, DA Kirschner, DB Teplow
Proceedings of the National Academy of Sciences 93 (3), 1125-1129, 1996
10271996
Structure–neurotoxicity relationships of amyloid β-protein oligomers
K Ono, MM Condron, DB Teplow
Proceedings of the National Academy of Sciences 106 (35), 14745-14750, 2009
8992009
Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis
MD Kirkitadze, MM Condron, DB Teplow
Journal of molecular biology 312 (5), 1103-1119, 2001
8402001
Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin
M Moos, R Tacke, H Scherer, D Teplow, K Früh, M Schachner
Nature 334 (6184), 701-703, 1988
7821988
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
N Stahl, MA Baldwin, DB Teplow, L Hood, BW Gibson, AL Burlingame, ...
Biochemistry 32 (8), 1991-2002, 1993
7811993
Amyloid β-protein assembly and Alzheimer disease
R Roychaudhuri, M Yang, MM Hoshi, DB Teplow
Journal of Biological Chemistry 284 (8), 4749-4753, 2009
7712009
Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies
MD Kirkitadze, G Bitan, DB Teplow
Journal of neuroscience research 69 (5), 567-577, 2002
7352002
beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
C Haass, AY Hung, MG Schlossmacher, DB Teplow, DJ Selkoe
Journal of Biological Chemistry 268 (5), 3021-3024, 1993
7061993
Kinetic theory of fibrillogenesis of amyloid β-protein
A Lomakin, DB Teplow, DA Kirschner, GB Benedek
Proceedings of the National Academy of Sciences 94 (15), 7942-7947, 1997
6781997
Presenilin‐dependent γ‐secretase processing of β‐amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
M Sastre, H Steiner, K Fuchs, A Capell, G Multhaup, MM Condron, ...
EMBO reports, 2001
6682001
Munumbicins, wide-spectrum antibiotics produced by Streptomyces NRRL 30562, endophytic on Kennedia nigriscans
UF Castillo, GA Strobel, EJ Ford, WM Hess, H Porter, JB Jensen, H Albert, ...
Microbiology 148 (9), 2675-2685, 2002
6032002
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