christophe hue
christophe hue
Adresse e-mail validée de inserm.fr
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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
M Cavazzana-Calvo, S Hacein-Bey, G de Saint Basile, F Gross, E Yvon, ...
Science 288 (5466), 669-672, 2000
30722000
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
S Hacein-Bey-Abina, F Le Deist, F Carlier, C Bouneaud, C Hue, ...
New England Journal of Medicine 346 (16), 1185-1193, 2002
12962002
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH Brugman, ...
The Journal of clinical investigation 117 (8), 2225-2232, 2007
2642007
Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome
LT Roumenina, M Jablonski, C Hue, J Blouin, JD Dimitrov, ...
Blood, The Journal of the American Society of Hematology 114 (13), 2837-2845, 2009
1532009
Failure of SCID-X1 gene therapy in older patients
AJ Thrasher, S Hacein-Bey-Abina, HB Gaspar, S Blanche, EG Davies, ...
Blood 105 (11), 4255-4257, 2005
1242005
A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function
LT Roumenina, M Frimat, EC Miller, F Provot, MA Dragon-Durey, ...
Blood 119 (18), 4182-4191, 2012
1142012
Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
EC Schramm, LT Roumenina, T Rybkine, S Chauvet, P Vieira-Martins, ...
Blood, The Journal of the American Society of Hematology 125 (15), 2359-2369, 2015
892015
Clonal evidence for the transduction of CD34+ cells with lymphomyeloid differentiation potential and self-renewal capacity in the SCID-X1 gene therapy trial
M Schmidt, S Hacein-Bey-Abina, M Wissler, F Carlier, A Lim, C Prinz, ...
Blood 105 (7), 2699-2706, 2005
852005
Complement factor B mutations in atypical hemolytic uremic syndrome—disease-relevant or benign?
MC Marinozzi, L Vergoz, T Rybkine, S Ngo, S Bettoni, A Pashov, M Cayla, ...
Journal of the American Society of Nephrology 25 (9), 2053-2065, 2014
722014
Long-term immune reconstitution in RAG-1-deficient mice treated by retroviral gene therapy: a balance between efficiency and toxicity
C Lagresle-Peyrou, F Yates, M Malassis-Séris, C Hue, E Morillon, ...
Blood 107 (1), 63-72, 2006
562006
Optimization of retroviral gene transfer protocol to maintain the lymphoid potential of progenitor cells
S Hacein-Bey, F Gross, P Nusbaum, C Hue, Y Hamel, A Fischer, ...
Human gene therapy 12 (3), 291-301, 2001
402001
Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance
ME Dumas, AR Rothwell, L Hoyles, T Aranias, J Chilloux, S Calderari, ...
Cell reports 20 (1), 136-148, 2017
382017
Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome
H Waller-Evans, C Hue, J Fearnside, AR Rothwell, HE Lockstone, ...
PLoS One 8 (12), e82825, 2013
342013
Restoration of human B-cell differentiation into NOD-SCID mice engrafted with gene-corrected CD34+ cells isolated from Artemis or RAG1-deficient patients
C Lagresle-Peyrou, F Benjelloun, C Hue, I Andre-Schmutz, D Bonhomme, ...
Molecular Therapy 16 (2), 396-403, 2008
302008
Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men
MR Diawara, C Hue, SP Wilder, N Venteclef, J Aron-Wisnewsky, J Scott, ...
PLoS One 9 (3), e91375, 2014
262014
Eculizumab in an anephric patient with atypical haemolytic uraemic syndrome and advanced vascular lesions
ZD Békássy, AC Kristoffersson, M Cronqvist, LT Roumenina, T Rybkine, ...
Nephrology Dialysis Transplantation 28 (11), 2899-2907, 2013
252013
Competition within the early B-cell compartment conditions B-cell reconstitution after hematopoietic stem cell transplantation in nonirradiated recipients
A Liu, CAJ Vosshenrich, C Lagresle-Peyrou, M Malassis-Seris, C Hue, ...
Blood 108 (4), 1123-1128, 2006
172006
Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series
ME Dumas, C Domange, S Calderari, AR Martínez, R Ayala, SP Wilder, ...
Genome medicine 8 (1), 1-15, 2016
142016
Modulatory role of the anti-apoptotic protein kinase CK2 in the sub-cellular localization of Fas associated death domain protein (FADD)
V Vilmont, O Filhol, AM Hesse, Y Couté, C Hue, L Rémy-Tourneur, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (11), 2885-2896, 2015
142015
Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons
S Calderari, M Ria, C Gérard, TC Nogueira, O Villate, SC Collins, H Neil, ...
Genomics 110 (2), 98-111, 2018
92018
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