Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet V Corbel, M Stankiewicz, C Pennetier, D Fournier, J Stojan, E Girard, ... BMC biology 7 (1), 47, 2009 | 250 | 2009 |
Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production M Dimitrov, JR Alattia, T Lemmin, R Lehal, A Fligier, J Houacine, ... Nature Communications 4, 2013 | 109 | 2013 |
Calcium-sensing receptor attenuates AVP-induced aquaporin-2 expression via a calmodulin-dependent mechanism M Bustamante, U Hasler, V Leroy, S de Seigneux, M Dimitrov, ... Journal of the American Society of Nephrology 19 (1), 109-116, 2008 | 105 | 2008 |
NF-κB modulates aquaporin-2 transcription in renal collecting duct principal cells U Hasler, V Leroy, US Jeon, R Bouley, M Dimitrov, JA Kim, D Brown, ... Journal of Biological Chemistry 283 (42), 28095-28105, 2008 | 86 | 2008 |
Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production H Gerber, F Wu, M Dimitrov, GMG Osuna, PC Fraering Journal of Biological Chemistry, jbc. M116. 754101, 2017 | 74 | 2017 |
Label-free imaging of cerebral β-Amyloidosis with extended-focus optical coherence microscopy T Bolmont, A Bouwens, C Pache, M Dimitrov, C Berclaz, M Villiger, ... The Journal of Neuroscience 32 (42), 14548-14556, 2012 | 63 | 2012 |
The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation I Hussain, J Fabrègue, L Anderes, S Ousson, F Borlat, V Eligert, S Berger, ... Journal of Biological Chemistry 288 (4), 2521-2531, 2013 | 57 | 2013 |
Perturbations of the Straight Transmembrane α-Helical Structure of the Amyloid Precursor Protein Affect its Processing by γ-Secretase T Lemmin, M Dimitrov, PC Fraering, M Dal Peraro Journal of Biological Chemistry, jbc. M113. 470781, 2014 | 51 | 2014 |
Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence A Revandkar, ML Perciato, A Toso, A Alajati, J Chen, H Gerber, ... Nature Communications 7, 2016 | 46 | 2016 |
The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain S Mosser, JR Alattia, M Dimitrov, A Matz, J Pascual, BL Schneider, ... Human molecular genetics, ddu449, 2014 | 35 | 2014 |
Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila JR Alattia, T Kuraishi, M Dimitrov, I Chang, B Lemaitre, PC Fraering The FASEB Journal 25 (7), 2287-2295, 2011 | 34 | 2011 |
Highly efficient production of the Alzheimer's γ‐Secretase integral membrane protease complex by a multi‐gene stable integration approach JR Alattia, M Matasci, M Dimitrov, L Aeschbach, S Balasubramanian, ... Biotechnology and bioengineering, 2013 | 31 | 2013 |
Shedding of neurexin 3β ectodomain by ADAM10 releases a soluble fragment that affects the development of newborn neurons E Borcel, M Palczynska, M Krzisch, M Dimitrov, G Ulrich, N Toni, ... Scientific Reports 6, 2016 | 22 | 2016 |
Production of active glycosylation‐deficient γ‐secretase complex for crystallization studies AR López, M Dimitrov, H Gerber, V Braman, DL Hacker, FM Wurm, ... Biotechnology and bioengineering 112 (12), 2516-2526, 2015 | 9 | 2015 |
Generation of monoclonal antibody fragments binding the native γ-secretase complex for use in structural studies JR Alattia, C Schweizer, M Cacquevel, M Dimitrov, L Aeschbach, ... Biochemistry 51 (44), 8779-8790, 2012 | 4 | 2012 |
The Amyloid Precursor Protein Maintains an Ideal&Alpha-Helical Conformation in the Lipid Bilayer T Lemmin, M Dimitrov, P Fraering, M Dal Peraro Biophysical Journal 106 (2), 53a, 2014 | | 2014 |
Pharmacological and biochemical assessment of γ-secretase-mediated APP processing involved in Alzheimer" s disease M Dimitrov EPFL, 2014 | | 2014 |
Intrinsic Transmembrane Flexibility of the Amyloid Precursor Protein Explored by Molecular Simulations T Lemmin, M Dimitrov, P Fraering, M Dal Peraro Biophysical Journal 104, 226, 2013 | | 2013 |
Identical γ-secretase-dependent production of Amyloid Precursor Protein Intracellular Domains from β-and α-carboxy-terminal fragments APP-C99 and APP-C83. J Houacine, M Dimitrov, SG Hays, L Aeschbach, PC Fraering The Gamma-Secretase-Mediated Proteolytic Processing of APP C-Terminal …, 2011 | | 2011 |