Etienne Patin
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Natural selection has driven population differentiation in modern humans
LB Barreiro, G Laval, H Quach, E Patin, L Quintana-Murci
Nature genetics 40 (3), 340-345, 2008
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
LB Barreiro, M Ben-Ali, H Quach, G Laval, E Patin, JK Pickrell, C Bouchier, ...
PLoS genetics 5 (7), e1000562, 2009
Genetic adaptation and neandertal admixture shaped the immune system of human populations
H Quach, M Rotival, J Pothlichet, YHE Loh, M Dannemann, N Zidane, ...
Cell 167 (3), 643-656. e17, 2016
Genomic signatures of selective pressures and introgression from archaic hominins at human innate immunity genes
M Deschamps, G Laval, M Fagny, Y Itan, L Abel, JL Casanova, E Patin, ...
The American Journal of Human Genetics 98 (1), 5-21, 2016
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors
E Patin, M Hasan, J Bergstedt, V Rouilly, V Libri, A Urrutia, C Alanio, ...
Nature immunology 19 (3), 302-314, 2018
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
E Patin, M Lopez, R Grollemund, P Verdu, C Harmant, H Quach, G Laval, ...
Science 356 (6337), 543-546, 2017
The human gene damage index as a gene-level approach to prioritizing exome variants
Y Itan, L Shang, B Boisson, E Patin, A Bolze, M Moncada-Vélez, E Scott, ...
Proceedings of the National Academy of Sciences 112 (44), 13615-13620, 2015
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter–gatherers and Bantu-speaking farmers
L Quintana-Murci, H Quach, C Harmant, F Luca, B Massonnet, E Patin, ...
Proceedings of the National Academy of Sciences 105 (5), 1596-1601, 2008
Inferring the demographic history of African farmers and Pygmy hunter–gatherers using a multilocus resequencing data set
E Patin, G Laval, LB Barreiro, A Salas, O Semino, ...
PLoS genetics 5 (4), e1000448, 2009
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges
B Piasecka, D Duffy, A Urrutia, H Quach, E Patin, C Posseme, J Bergstedt, ...
Proceedings of the National Academy of Sciences 115 (3), E488-E497, 2018
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
E Patin, Z Kutalik, J Guergnon, S Bibert, B Nalpas, E Jouanguy, ...
Gastroenterology 143 (5), 1244-1252. e12, 2012
Evolutionary genetic dissection of human interferons
J Manry, G Laval, E Patin, S Fornarino, Y Itan, M Fumagalli, M Sironi, ...
Journal of Experimental Medicine 208 (13), 2747-2759, 2011
Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia
A Bolze, N Mahlaoui, M Byun, B Turner, N Trede, SR Ellis, A Abhyankar, ...
Science 340 (6135), 976-978, 2013
IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non‐1 HCV genotypes
PY Bochud, S Bibert, Z Kutalik, E Patin, J Guergnon, B Nalpas, ...
Hepatology 55 (2), 384-394, 2012
Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians
C Louicharoen, E Patin, R Paul, I Nuchprayoon, B Witoonpanich, ...
Science 326 (5959), 1546-1549, 2009
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
R Martínez-Barricarte, JG Markle, CS Ma, EK Deenick, N Ramírez-Alejo, ...
Science immunology 3 (30), eaau6759, 2018
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
S Boisson-Dupuis, N Ramirez-Alejo, Z Li, E Patin, G Rao, G Kerner, ...
Science immunology 3 (30), eaau8714, 2018
Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections
A Crequer, A Troeger, E Patin, CS Ma, C Picard, V Pedergnana, C Fieschi, ...
The Journal of clinical investigation 122 (9), 3239-3247, 2012
Inherited MST1 deficiency underlies susceptibility to EV-HPV infections
A Crequer, C Picard, E Patin, A D’Amico, A Abhyankar, M Munzer, ...
Public Library of Science 7 (8), e44010, 2012
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