Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions DG Lupiáñez, K Kraft, V Heinrich, P Krawitz, F Brancati, E Klopocki, ... Cell 161 (5), 1012-1025, 2015 | 2291 | 2015 |
Formation of new chromatin domains determines pathogenicity of genomic duplications M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ... Nature 538 (7624), 265-269, 2016 | 737 | 2016 |
Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice K Kraft, S Geuer, AJ Will, WL Chan, C Paliou, M Borschiwer, I Harabula, ... Cell reports 10 (5), 833-839, 2015 | 259 | 2015 |
ecDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021 | 226 | 2021 |
Polymer physics predicts the effects of structural variants on chromatin architecture S Bianco, DG Lupiáñez, AM Chiariello, C Annunziatella, K Kraft, ... Nature genetics 50 (5), 662-667, 2018 | 202 | 2018 |
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis BK Kragesteen, M Spielmann, C Paliou, V Heinrich, R Schöpflin, ... Nature genetics 50 (10), 1463-1473, 2018 | 195 | 2018 |
Identifying cis elements for spatiotemporal control of mammalian DNA replication J Sima, A Chakraborty, V Dileep, M Michalski, KN Klein, NP Holcomb, ... Cell 176 (4), 816-830. e18, 2019 | 184 | 2019 |
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations K Kraft, A Magg, V Heinrich, C Riemenschneider, R Schöpflin, ... Nature cell biology 21 (3), 305-310, 2019 | 149 | 2019 |
Xist ribonucleoproteins promote female sex-biased autoimmunity DR Dou, Y Zhao, JA Belk, Y Zhao, KM Casey, DC Chen, R Li, B Yu, ... Cell 187 (3), 733-749. e16, 2024 | 118 | 2024 |
Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A P Kuss, K Kraft, J Stumm, D Ibrahim, P Vallecillo-Garcia, S Mundlos, ... Developmental biology 385 (1), 83-93, 2014 | 87 | 2014 |
Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation K Kraft, KE Yost, SE Murphy, A Magg, Y Long, MR Corces, JM Granja, ... Proceedings of the National Academy of Sciences 119 (22), e2201883119, 2022 | 69 | 2022 |
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases SK Wang, S Nair, R Li, K Kraft, A Pampari, A Patel, JB Kang, C Luong, ... Cell genomics 2 (8), 2022 | 52 | 2022 |
Bidirectional epigenetic editing reveals hierarchies in gene regulation NM Pacalin, Z Steinhart, Q Shi, JA Belk, D Dorovskyi, K Kraft, KR Parker, ... Nature biotechnology, 1-14, 2024 | 12 | 2024 |
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma K Okonechnikov, A Camgöz, O Chapman, S Wani, DE Park, JM Hübner, ... Nature Communications 14 (1), 2300, 2023 | 12 | 2023 |
Identification of cis elements for spatio-temporal control of DNA replication J Sima, A Chakraborty, V Dileep, M Michalski, JC Rivera-Mulia, ... bioRxiv, 285650, 2018 | 3 | 2018 |
Enhancer activation from transposable elements in extrachromosomal DNA K Kraft, SE Murphy, MG Jones, Q Shi, A Bhargava-Shah, C Luong, ... bioRxiv, 2024 | 1 | 2024 |
XIST ribonucleoproteins promote female sex-biased autoimmunity DR Dou, Y Zhao, JA Belk, Y Zhao, KM Casey, DC Chen, R Li, B Yu, ... bioRxiv, 2022.11. 05.515306, 2022 | 1 | 2022 |
OMIC-01. THE LANDSCAPE OF EXTRACHROMOSOMAL CIRCULAR DNA IN MEDULLOBLASTOMA SUBGROUPS O Chapman, J Luebeck, S Wang, A Garancher, J Larson, J Lange, ... Neuro-oncology 23 (Supplement_1), i37-i37, 2021 | 1 | 2021 |
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D B Chowdhury, K Zhu, C Li, J Luebeck, OS Chapman, K Kraft, S Zhang, ... bioRxiv, 2025.02. 01.636064, 2025 | | 2025 |
EPEN-18. Oncogenic 3D genome conformations identify novel therapeutic targets in ependymoma K Okonechnikov, A Camgöz, DE Park, O Chapman, JM Hübner, A Jenseit, ... Neuro-Oncology 24 (Supplement_1), i42-i42, 2022 | | 2022 |