Daniel E. Speiser
Daniel E. Speiser
Professor in Immunology and Oncology
Verified email at - Homepage
Cited by
Cited by
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ...
European journal of immunology 49 (10), 1457-1973, 2019
Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
WC Yeh, A Shahinian, D Speiser, J Kraunus, F Billia, A Wakeham, ...
Immunity 7 (5), 715-725, 1997
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
L Baitsch, P Baumgaertner, E Devêvre, SK Raghav, A Legat, L Barba, ...
The Journal of clinical investigation 121 (6), 2350-2360, 2011
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
DE Speiser, D Liénard, N Rufer, V Rubio-Godoy, D Rimoldi, F Lejeune, ...
The Journal of clinical investigation 115 (3), 739-746, 2005
Intratumoral Tcf1+ PD-1+ CD8+ T cells with stem-like properties promote tumor control in response to vaccination and checkpoint blockade immunotherapy
I Siddiqui, K Schaeuble, V Chennupati, SAF Marraco, S Calderon-Copete, ...
Immunity 50 (1), 195-211. e10, 2019
Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide
V Appay, DE Speiser, N Rufer, S Reynard, C Barbey, JC Cerottini, ...
European journal of immunology 36 (7), 1805-1814, 2006
High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals
MJ Pittet, D Valmori, PR Dunbar, DE Speiser, D Liénard, F Lejeune, ...
The Journal of experimental medicine 190 (5), 705-716, 1999
Defining ‘T cell exhaustion’
CU Blank, WN Haining, W Held, PG Hogan, A Kallies, E Lugli, RC Lynn, ...
Nature Reviews Immunology 19 (11), 665-674, 2019
Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation
MF Bachmann, K McKall-Faienza, R Schmits, D Bouchard, J Beach, ...
Immunity 7 (4), 549-557, 1997
Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients
E Romano, M Kusio-Kobialka, PG Foukas, P Baumgaertner, C Meyer, ...
Proceedings of the National Academy of Sciences 112 (19), 6140-6145, 2015
Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab
C Meyer, L Cagnon, CM Costa-Nunes, P Baumgaertner, N Montandon, ...
Cancer Immunology, Immunotherapy 63 (3), 247-257, 2014
Classification of current anticancer immunotherapies
L Galluzzi, E Vacchelli, JM Bravo-San Pedro, A Buqué, L Senovilla, ...
Oncotarget 5 (24), 12472, 2014
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data
J Racle, K de Jonge, P Baumgaertner, DE Speiser, D Gfeller
elife 6, 2017
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes
P Romero, A Zippelius, I Kurth, MJ Pittet, C Touvrey, EM Iancu, P Corthesy, ...
The Journal of Immunology 178 (7), 4112-4119, 2007
Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
C Jandus, G Bioley, JP Rivals, J Dudler, D Speiser, P Romero
Arthritis & Rheumatism: Official Journal of the American College of …, 2008
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
SI Nikolaev, D Rimoldi, C Iseli, A Valsesia, D Robyr, C Gehrig, ...
Nature genetics 44 (2), 133-139, 2012
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance
A Zippelius, P Batard, V Rubio-Godoy, G Bioley, D Liénard, F Lejeune, ...
Cancer research 64 (8), 2865-2873, 2004
Regulatory circuits of T cell function in cancer
DE Speiser, PC Ho, G Verdeil
Nature Reviews Immunology 16 (10), 599-611, 2016
Self antigens expressed by solid tumors do not efficiently stimulate naive or activated T cells: implications for immunotherapy
DE Speiser, R Miranda, A Zakarian, MF Bachmann, K McKall-Faienza, ...
The Journal of experimental medicine 186 (5), 645-653, 1997
Anti–CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response
P Kvistborg, D Philips, S Kelderman, L Hageman, C Ottensmeier, ...
Science translational medicine 6 (254), 254ra128-254ra128, 2014
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