| MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis CM Koh, M Bezzi, DHP Low, WX Ang, SX Teo, FPH Gay, M Al-Haddawi, ... Nature 523 (7558), 96-100, 2015 | 374 | 2015 |
| PTBP1-mediated alternative splicing regulates the inflammatory secretome and the pro-tumorigenic effects of senescent cells A Georgilis, S Klotz, CJ Hanley, N Herranz, B Weirich, B Morancho, ... Cancer cell 34 (1), 85-102. e9, 2018 | 173 | 2018 |
| Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death KB Wee, BD Aguda Biophysical journal 91 (3), 857-865, 2006 | 126 | 2006 |
| Transition to Quorum Sensing in an Agrobacterium Population: A Stochastic Model AB Goryachev, DJ Toh, KB Wee, T Lee, HB Zhang, LH Zhang PLoS computational biology 1 (4), e37, 2005 | 90 | 2005 |
| Oscillations of the p53-Akt network: implications on cell survival and death KB Wee, U Surana, BD Aguda PloS one 4 (2), e4407, 2009 | 83 | 2009 |
| SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements DV Do, B Strauss, E Cukuroglu, I Macaulay, KB Wee, TX Hu, RDLM Igor, ... Cell discovery 4 (1), 33, 2018 | 59 | 2018 |
| RNAi reveals phase-specific global regulators of human somatic cell reprogramming CXD Toh, JW Chan, ZS Chong, HF Wang, HC Guo, S Satapathy, D Ma, ... Cell Reports 15 (12), 2597-2607, 2016 | 55 | 2016 |
| Dynamics of Co-Transcriptional Pre-mRNA Folding Influences the Induction of Dystrophin Exon Skipping by Antisense Oligonucleotides KB Wee, ZAD Pramono, JL Wang, KF MacDorman, PS Lai, WC Yee Plos one 3 (3), e1844, 2008 | 51 | 2008 |
| MBNL1 alternative splicing isoforms play opposing roles in cancer T Tabaglio, DHP Low, WKL Teo, PA Goy, P Cywoniuk, H Wollmann, J Ho, ... Life science alliance 1 (5), 2018 | 49 | 2018 |
| Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia Y Zhou, C Han, E Wang, AH Lorch, V Serafin, BK Cho, BT Gutierrez Diaz, ... Cancer discovery 10 (9), 1388-1409, 2020 | 37 | 2020 |
| Dual masking of specific negative splicing regulatory elements resulted in maximal exon 7 inclusion of SMN2 gene PW Pao, KB Wee, WC Yee, ZA DwiPramono Molecular Therapy 22 (4), 854-861, 2014 | 32 | 2014 |
| HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness JSY Ho, F Di Tullio, M Schwarz, D Low, D Incarnato, F Gay, T Tabaglio, ... Elife 10, e59654, 2021 | 30 | 2021 |
| A prospective study in the rational design of efficient antisense oligonucleotides for exon skipping in DMD gene ZAD Pramono, KB Wee, JL Wang, YJ Chen, QB Xiong, PS Lai, WC Yee Human Gene Therapy, 2012 | 30 | 2012 |
| Transcription factor oscillations induce differential gene expressions KB Wee, WK Yio, U Surana, KH Chiam Biophysical journal 102 (11), 2413-2423, 2012 | 28 | 2012 |
| PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis S Mzoughi, JY Fong, D Papadopoli, CM Koh, L Hulea, P Pigini, F Di Tullio, ... Nature communications 11 (1), 3520, 2020 | 25 | 2020 |
| Induced-decay of glycine decarboxylase transcripts as an anticancer therapeutic strategy for non-small-cell lung carcinoma J Lin, JHJ Lee, K Paramasivam, E Pathak, Z Wang, ZAD Pramono, B Lim, ... Molecular Therapy-Nucleic Acids 9, 263-273, 2017 | 24 | 2017 |
| Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC‐driven hepatocellular carcinoma DKH Thng, TB Toh, P Pigini, L Hooi, YY Dan, PKH Chow, GK Bonney, ... Bioengineering & Translational Medicine 8 (1), e10363, 2023 | 4 | 2023 |
| Splice-switching antisense oligonucleotides as a targeted intrinsic engineering tool for generating armored redirected T cells E Ceccarello, T Tabaglio, S Koh, V Oei, W Teo, OJ Jonathan, A Pavesi, ... Nucleic acid therapeutics 31 (2), 145-154, 2021 | 4 | 2021 |
| Discovery of influenza A virus sequence pairs and their combinations for simultaneous heterosubtypic targeting that hedge against antiviral resistance KB Wee, RTC Lee, J Lin, ZAD Pramono, S Maurer-Stroh PLOS Computational Biology 12 (1), e1004663, 2016 | 2 | 2016 |
| Splice-switching oligonucleotides as therapeutics for citrin deficiency patients with a novel deep intronic variant K Oishi, JR Ow, E Imagawa, WY Cher, V Ramadass, T Tabaglio, ... Molecular Genetics and Metabolism 141 (4), 108318, 2024 | | 2024 |
Karl F. MacDormanAssociate Dean, Luddy School of Informatics, Computing, and Engineering, Indiana UniversityVerified email at indiana.edu
