|Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes|
AD Elmezayen, A Al-Obaidi, AT Şahin, K Yelekçi
Journal of Biomolecular Structure and Dynamics, 1-13, 2020
|Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies|
G Bora-Tatar, D Dayangaç-Erden, AS Demir, S Dalkara, K Yelekçi, ...
Bioorganic & medicinal chemistry 17 (14), 5219-5228, 2009
|New pyrazoline bearing 4 (3H)-quinazolinone inhibitors of monoamine oxidase: Synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity|
N Gökhan-Kelekçi, S Koyunoğlu, S Yabanoğlu, K Yelekçi, Ö Özgen, ...
Bioorganic & medicinal chemistry 17 (2), 675-689, 2009
|Docking studies on monoamine oxidase-B inhibitors: Estimation of inhibition constants (Ki) of a series of experimentally tested compounds|
M Toprakçí, K Yelekçi
Bioorganic & medicinal chemistry letters 15 (20), 4438-4446, 2005
|A computational study on the amine-oxidation mechanism of monoamine oxidase: insight into the polar nucleophilic mechanism|
SS Erdem, Ö Karahan, İ Yıldız, K Yelekçi
Organic & biomolecular chemistry 4 (4), 646-658, 2006
|Drug design for CNS diseases: polypharmacological profiling of compounds using cheminformatic, 3D-QSAR and virtual screening methodologies|
K Nikolic, L Mavridis, T Djikic, J Vucicevic, D Agbaba, K Yelekci, ...
Frontiers in neuroscience 10, 265, 2016
|Histone Deacetylase Inhibition Activity and Molecular Docking of (E )‐Resveratrol: Its Therapeutic Potential in Spinal Muscular Atrophy|
D Dayangaç‐Erden, G Bora, P Ayhan, C Kocaefe, S Dalkara, K Yelekçi, ...
Chemical biology & drug design 73 (3), 355-364, 2009
|Synthesis of some novel hydrazone and 2-pyrazoline derivatives: Monoamine oxidase inhibitory activities and docking studies|
B Evranos-Aksöz, S Yabanoğlu-Çiftçi, G Uçar, K Yelekçi, R Ertan
Bioorganic & medicinal chemistry letters 24 (15), 3278-3284, 2014
|Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors|
N Gökhan-Kelekçi, ÖÖ Şimşek, A Ercan, K Yelekçi, ZS Şahin, Ş Işık, ...
Bioorganic & medicinal chemistry 17 (18), 6761-6772, 2009
|Electron spin resonance studies of monoamine oxidase B. First direct evidence for a substrate radical intermediate|
K Yelekci, X Lu, RB Silverman
Journal of the American Chemical Society 111 (3), 1138-1140, 1989
|Observation of a flavin semiquinone in the resting state of monoamine oxidase B by electron paramagnetic resonance and electron nuclear double resonance spectroscopy|
VJ DeRose, JCG Woo, WP Hawe, BM Hoffman, RB Silverman, K Yelekci
Biochemistry 35 (34), 11085-11091, 1996
|Docking of novel reversible monoamine oxidase-B inhibitors: efficient prediction of ligand binding sites and estimation of inhibitors thermodynamic properties|
K Yelekçi, Ö Karahan, M Toprakçı
Journal of neural transmission 114 (6), 725, 2007
|Computer modeling of oxygen containing heptylamines as monoamine oxidase inactivators|
SS Erdem, K Yelekçi
Journal of Molecular Structure: THEOCHEM 572 (1-3), 97-106, 2001
|Identification of potential isoform-selective histone deacetylase inhibitors for cancer therapy: A combined approach of structure-based virtual screening, ADMET prediction and …|
AI Uba, K Yelekçi
Journal of Biomolecular Structure and Dynamics 36 (12), 3231-3245, 2018
|cis‐cyclopropylamines as mechanism‐based inhibitors of monoamine oxidases|
T Malcomson, K Yelekci, MT Borrello, A Ganesan, E Semina, N De Kimpe, ...
The FEBS journal 282 (16), 3190-3198, 2015
|Flavonoids from Sideritis species: human monoamine oxidase (hMAO) inhibitory activities, molecular docking studies and crystal structure of xanthomicrol|
FP Turkmenoglu, İ Baysal, S Ciftci-Yabanoglu, K Yelekci, H Temel, ...
Molecules 20 (5), 7454-7473, 2015
|In silico design of novel and highly selective lysine-specific histone demethylase inhibitors|
ED Akdoğan, B Erman, K Yelekçi
Turkish Journal of Chemistry 35 (4), 523-542, 2011
|Homology modeling of human histone deacetylase 10 and design of potential selective inhibitors|
A Ibrahim Uba, K Yelekçi
Journal of Biomolecular Structure and Dynamics 37 (14), 3627-3636, 2019
|Synthesis and screening of human monoamine oxidase‐A inhibitor effect of new 2‐pyrazoline and hydrazone derivatives|
B Evranos‐Aksöz, İ Baysal, S Yabanoğlu‐Çiftçi, T Djikic, K Yelekçi, ...
Archiv der Pharmazie 348 (10), 743-756, 2015
|Evaluation of selective human MAO inhibitory activities of some novel pyrazoline derivatives|
U Salgın-Gökşen, S Yabanoğlu-Çiftçi, A Ercan, K Yelekçi, G Uçar, ...
Journal of Neural Transmission 120 (6), 863-873, 2013