Stephen Clark
Stephen Clark
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Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity
C Angermueller, SJ Clark, HJ Lee, IC Macaulay, MJ Teng, TX Hu, ...
Nature methods 13 (3), 229-232, 2016
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, ...
Nature communications 9 (1), 1-9, 2018
Joint Profiling Of Chromatin Accessibility, DNA Methylation And Transcription In Single Cells
SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, F Krueger, ...
bioRxiv, 138685, 2017
Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity
SJ Clark, HJ Lee, SA Smallwood, G Kelsey, W Reik
Genome biology 17 (1), 1-10, 2016
Multi-omics profiling of mouse gastrulation at single-cell resolution
R Argelaguet, SJ Clark, H Mohammed, LC Stapel, C Krueger, ...
Nature 576 (7787), 487-491, 2019
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq)
SJ Clark, SA Smallwood, HJ Lee, F Krueger, W Reik, G Kelsey
Nature protocols 12 (3), 534-547, 2017
Genome-wide bisulfite sequencing in zygotes identifies demethylation targets and maps the contribution of TET3 oxidation
JR Peat, W Dean, SJ Clark, F Krueger, SA Smallwood, G Ficz, JK Kim, ...
Cell reports 9 (6), 1990-2000, 2014
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells
I Hernando-Herraez, B Evano, T Stubbs, PH Commere, MJ Bonder, ...
Nature communications 10 (1), 1-11, 2019
Continuous histone replacement by Hira is essential for normal transcriptional regulation and de novo DNA methylation during mouse oogenesis
B Nashun, PWS Hill, SA Smallwood, G Dharmalingam, R Amouroux, ...
Molecular cell 60 (4), 611-625, 2015
Association of sirtuin 1 (SIRT1) gene SNPs and transcript expression levels with severe obesity
SJ Clark, M Falchi, B Olsson, P Jacobson, S Cauchi, B Balkau, M Marre, ...
Obesity 20 (1), 178-185, 2012
Genome-scale oscillations in DNA methylation during exit from pluripotency
S Rulands, HJ Lee, SJ Clark, C Angermueller, SA Smallwood, F Krueger, ...
Cell systems 7 (1), 63-76. e12, 2018
Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity
SM Linker, L Urban, SJ Clark, M Chhatriwala, S Amatya, DJ McCarthy, ...
Genome biology 20 (1), 1-14, 2019
The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances
A Monteagudo-Sánchez, JR Hernandez Mora, C Simon, A Burton, ...
Nucleic acids research 48 (20), 11394-11407, 2020
Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis
J Castillo‐Fernandez, E Herrera‐Puerta, H Demond, SJ Clark, CW Hanna, ...
Aging cell 19 (12), e13278, 2020
Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification
R Argelaguet, H Mohammed, S Clark, C Stapel, C Krueger, CA Kapourani, ...
bioRxiv, 519207, 2019
Enhancer priming by H3K4 methylation safeguards germline competence
T Bleckwehl, K Schaaf, G Crispatzu, P Respuela, M Bartusel, L Benson, ...
bioRxiv, 2020
Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates
F Olmeda, T Lohoff, S Clark, L Benson, F Krueger, W Reik, S Rulands
bioRxiv, 2020.12. 30.424823, 2021
Dppa2/4 target chromatin bivalency enabling multi-lineage commitment
MA Eckersley-Maslin, A Parry, M Blotenburg, C Krueger, VNR Franklin, ...
bioRxiv, 832873, 2019
Inference of emergent spatio-temporal processes in single-cell genomics
F Olmeda, T Lohoff, S Clark, L Benson, F Krueger, W Reik, S Rulands
Bulletin of the American Physical Society, 2021
Single-cell bisulfite sequencing of spermatozoa from lean and obese humans reveals potential for the transmission of epimutations
E Andersen, S Clark, L Ingerslev, L Lundell, W Reik, R Barrčs
bioRxiv, 2021
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