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Joanna Loizou
Joanna Loizou
Director of Translational Medicine, Early Oncology, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
R Murr, JI Loizou, YG Yang, C Cuenin, H Li, ZQ Wang, Z Herceg
Nature cell biology 8 (1), 91-99, 2006
6942006
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ...
Nature 508 (7495), 222-227, 2014
4352014
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks
JI Loizou, SF El-Khamisy, A Zlatanou, DJ Moore, DW Chan, J Qin, ...
Cell 117 (1), 17-28, 2004
3722004
DNA replication stress: causes, resolution and disease
A Mazouzi, G Velimezi, JI Loizou
Experimental cell research 329 (1), 85-93, 2014
2612014
Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1
T Iftner, M Elbel, B Schopp, T Hiller, JI Loizou, KW Caldecott, ...
The EMBO journal 21 (17), 4741-4748, 2002
2002002
Validating the concept of mutational signatures with isogenic cell models
X Zou, M Owusu, R Harris, SP Jackson, JI Loizou, S Nik-Zainal
Nature communications 9 (1), 1744, 2018
1512018
Targeting the DNA repair enzyme polymerase θ in cancer therapy
A Schrempf, J Slyskova, JI Loizou
Trends in cancer 7 (2), 98-111, 2021
1022021
Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair
J Ferreira da Silva, GP Oliveira, EA Arasa-Verge, C Kagiou, A Moretton, ...
Nature communications 13 (1), 760, 2022
962022
Epigenetic information in chromatin: the code of entry for DNA repair
JI Loizou, R Murr, MG Finkbeiner, C Sawan, ZQ Wang, Z Herceg
Cell Cycle 5 (7), 696-701, 2006
702006
Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
NK Serwas, B Hoeger, RC Ardy, SV Stulz, Z Sui, N Memaran, M Meeths, ...
Nature communications 10 (1), 3106, 2019
642019
CDK6 antagonizes p53-induced responses during tumorigenesis
F Bellutti, AS Tigan, S Nebenfuehr, M Dolezal, M Zojer, R Grausenburger, ...
Cancer discovery 8 (7), 884-897, 2018
612018
Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities
K Unterhauser, L Pöltl, G Schneditz, S Kienesberger, RA Glabonjat, ...
Proceedings of the National Academy of Sciences 116 (9), 3774-3783, 2019
562019
Interplay between cellular metabolism and the DNA damage response in cancer
A Moretton, JI Loizou
Cancers 12 (8), 2051, 2020
532020
Competition between NBS1 and ATMIN controls ATM signaling pathway choice
T Zhang, K Penicud, C Bruhn, JI Loizou, N Kanu, ZQ Wang, A Behrens
Cell reports 2 (6), 1498-1504, 2012
482012
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
CD Conde, ÖY Petronczki, S Baris, KL Willmann, E Girardi, E Salzer, ...
The Journal of clinical investigation 129 (10), 4194-4206, 2019
462019
Repair of UV-induced DNA damage independent of nucleotide excision repair is masked by MUTYH
A Mazouzi, F Battistini, SC Moser, JF da Silva, M Wiedner, M Owusu, ...
Molecular cell 68 (4), 797-807. e7, 2017
462017
ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma
JI Loizou, R Sancho, N Kanu, DJ Bolland, F Yang, C Rada, AE Corcoran, ...
Cancer cell 19 (5), 587-600, 2011
412011
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia
B Maurer, H Nivarthi, B Wingelhofer, HTT Pham, M Schlederer, T Suske, ...
Haematologica 105 (2), 435, 2020
402020
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48
G Velimezi, L Robinson-Garcia, F Muñoz-Martínez, WW Wiegant, ...
Nature communications 9 (1), 2280, 2018
402018
Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool
JI Loizou, G Oser, V Shukla, C Sawan, R Murr, ZQ Wang, A Trumpp, ...
The Journal of Immunology 183 (10), 6422-6431, 2009
362009
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