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David A. Knowles
David A. Knowles
Columbia University & New York Genome Center
Adresse e-mail validée de columbia.edu - Page d'accueil
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Predicting splicing from primary sequence with deep learning
K Jaganathan, SK Panagiotopoulou, JF McRae, SF Darbandi, D Knowles, ...
Cell 176 (3), 535-548. e24, 2019
10482019
Mapping cis- and trans-regulatory effects across multiple tissues in twins
E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ...
Nature genetics 44 (10), 1084-1089, 2012
8542012
RNA splicing is a primary link between genetic variation and disease
YI Li, B Van De Geijn, A Raj, DA Knowles, AA Petti, D Golan, Y Gilad, ...
Science 352 (6285), 600-604, 2016
5482016
Opportunities and challenges for transcriptome-wide association studies
M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ...
Nature genetics 51 (4), 592-599, 2019
5272019
Annotation-free quantification of RNA splicing using LeafCutter
YI Li, DA Knowles, J Humphrey, AN Barbeira, SP Dickinson, HK Im, ...
Nature genetics 50 (1), 151-158, 2018
4742018
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
LA Becker, B Huang, G Bieri, R Ma, DA Knowles, P Jafar-Nejad, ...
Nature 544 (7650), 367-371, 2017
4472017
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
E Grundberg, E Meduri, JK Sandling, ÅK Hedman, S Keildson, A Buil, ...
The American Journal of Human Genetics 93 (5), 876-890, 2013
3652013
Batch effects and the effective design of single-cell gene expression studies
PY Tung, JD Blischak, CJ Hsiao, DA Knowles, JE Burnett, JK Pritchard, ...
Scientific reports 7 (1), 39921, 2017
3122017
Distinct epigenomic features in end-stage failing human hearts
M Movassagh, MK Choy, DA Knowles, L Cordeddu, S Haider, T Down, ...
Circulation 124 (22), 2411-2422, 2011
2742011
Gene expression changes with age in skin, adipose tissue, blood and brain
D Glass, A Viñuela, MN Davies, A Ramasamy, L Parts, D Knowles, ...
Genome biology 14 (7), 1-12, 2013
2692013
Fixed-form variational posterior approximation through stochastic linear regression
T Salimans, DA Knowles
Bayesian Analysis 8 (4), 837-882, 2013
2412013
Infer.NET 2.4
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2010
225*2010
Molecular choreography of acute exercise
K Contrepois, S Wu, KJ Moneghetti, D Hornburg, S Ahadi, MS Tsai, ...
Cell 181 (5), 1112-1130. e16, 2020
2162020
Infer.NET 2.5
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2012
191*2012
Gaussian Process Regression Networks
AG Wilson, DA Knowles, Z Ghahramani
Proceedings of the 29th International Conference on Machine Learning (ICML 2011), 2011
1902011
Landscape of stimulation-responsive chromatin across diverse human immune cells
D Calderon, MLT Nguyen, A Mezger, A Kathiria, F Müller, V Nguyen, ...
Nature genetics 51 (10), 1494-1505, 2019
1722019
Infinite sparse factor analysis and infinite independent components analysis
D Knowles, Z Ghahramani
Independent Component Analysis and Signal Separation: 7th International …, 2007
1662007
Nonparametric Bayesian sparse factor models with application to gene expression modeling
D Knowles, Z Ghahramani
1592011
Non-conjugate Variational Message Passing for Multinomial and Binary Regression
DA Knowles, TP Minka
Advances in Neural Information Processing Systems, 2011
1442011
Differential methylation of the TRPA1 promoter in pain sensitivity
JT Bell, AK Loomis, LM Butcher, F Gao, B Zhang, CL Hyde, J Sun, H Wu, ...
Nature communications 5 (1), 2978, 2014
1432014
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