David A. Knowles
David A. Knowles
Columbia University & New York Genome Center
Adresse e-mail validée de columbia.edu - Page d'accueil
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Mapping cis-and trans-regulatory effects across multiple tissues in twins
E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ...
Nature genetics 44 (10), 1084-1089, 2012
7662012
A community effort to assess and improve drug sensitivity prediction algorithms
JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ...
Nature biotechnology 32 (12), 1202-1212, 2014
5482014
RNA splicing is a primary link between genetic variation and disease
YI Li, B Van De Geijn, A Raj, DA Knowles, AA Petti, D Golan, Y Gilad, ...
Science 352 (6285), 600-604, 2016
4092016
Predicting splicing from primary sequence with deep learning
K Jaganathan, SK Panagiotopoulou, JF McRae, SF Darbandi, D Knowles, ...
Cell 176 (3), 535-548. e24, 2019
4052019
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
E Grundberg, E Meduri, JK Sandling, ÅK Hedman, S Keildson, A Buil, ...
The American Journal of Human Genetics 93 (5), 876-890, 2013
3222013
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
LA Becker, B Huang, G Bieri, R Ma, DA Knowles, P Jafar-Nejad, ...
Nature 544 (7650), 367-371, 2017
3102017
Annotation-free quantification of RNA splicing using LeafCutter
YI Li, DA Knowles, J Humphrey, AN Barbeira, SP Dickinson, HK Im, ...
Nature genetics 50 (1), 151-158, 2018
2602018
Opportunities and challenges for transcriptome-wide association studies
M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ...
Nature genetics 51 (4), 592-599, 2019
2322019
Batch effects and the effective design of single-cell gene expression studies
PY Tung, JD Blischak, CJ Hsiao, DA Knowles, JE Burnett, JK Pritchard, ...
Scientific reports 7 (1), 1-15, 2017
2322017
Distinct epigenomic features in end-stage failing human hearts
M Movassagh, MK Choy, DA Knowles, L Cordeddu, S Haider, T Down, ...
Circulation 124 (22), 2411-2422, 2011
2262011
Infer.NET 2.4
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2010
220*2010
Gene expression changes with age in skin, adipose tissue, blood and brain
D Glass, A Viñuela, MN Davies, A Ramasamy, L Parts, D Knowles, ...
Genome biology 14 (7), 1-12, 2013
2072013
Fixed-form variational posterior approximation through stochastic linear regression
T Salimans, DA Knowles
Bayesian Analysis 8 (4), 837-882, 2013
1952013
Infer.NET 2.5
T Minka, J Winn, J Guiver, D Knowles
Microsoft Research Cambridge http://research.microsoft.com/infernet, 2012
185*2012
Infinite sparse factor analysis and infinite independent components analysis
D Knowles, Z Ghahramani
International Conference on Independent Component Analysis and Signal …, 2007
1542007
Nonparametric Bayesian sparse factor models with application to gene expression modeling
D Knowles, Z Ghahramani
The Annals of Applied Statistics 5 (2B), 1534-1552, 2011
1392011
Gaussian Process Regression Networks
AG Wilson, DA Knowles, Z Ghahramani
Proceedings of the 29th International Conference on Machine Learning (ICML 2011), 2011
1352011
An infinite latent attribute model for network data
K Palla, D Knowles, Z Ghahramani
Proceedings of the 30th International Conference on Machine Learning, 2012
1282012
Non-conjugate Variational Message Passing for Multinomial and Binary Regression
DA Knowles, TP Minka
Advances in Neural Information Processing Systems, 2011
1232011
Differential methylation of the TRPA1 promoter in pain sensitivity
JT Bell, AK Loomis, LM Butcher, F Gao, B Zhang, CL Hyde, J Sun, H Wu, ...
Nature communications 5 (1), 1-11, 2014
1192014
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