Roland H. Wenger
Roland H. Wenger
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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
NV Iyer, LE Kotch, F Agani, SW Leung, E Laughner, RH Wenger, ...
Genes & development 12 (2), 149-162, 1998
Cellular adaptation to hypoxia: O2‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O2‐regulated gene expression
RH Wenger
The FASEB journal 16 (10), 1151-1162, 2002
Integration of oxygen signaling at the consensus HRE
RH Wenger, DP Stiehl, G Camenisch
Science's STKE 2005 (306), re12-re12, 2005
HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia
DM Stroka, T Burkhardt, I Desbaillets, RH Wenger, DAH Neil, C Bauer, ...
The FASEB Journal 15 (13), 2445-2453, 2001
Induction of HIF–1α in response to hypoxia is instantaneous
UR Jewell, I Kvietikova, A Scheid, C Bauer, RH Wenger, M Gassmann
The FASEB Journal 15 (7), 1312-1314, 2001
Oxygen (es) and the hypoxia-inducible factor-1.
RH Wenger, M Gassmann
Biological chemistry 378 (7), 609-616, 1997
Erythropoietin gene expression in human, monkey and murine brain
HH Marti, RH Wenger, LA Rivas, U Straumann, M Oigicaylioglu, V Henn, ...
European Journal of Neuroscience 8 (4), 666-676, 1996
Mammalian oxygen sensing, signalling and gene regulation
RH Wenger
Journal of Experimental Biology 203 (8), 1253-1263, 2000
Localization of specific erythropoietin binding sites in defined areas of the mouse brain.
M Digicaylioglu, S Bichet, HH Marti, RH Wenger, LA Rivas, C Bauer, ...
Proceedings of the National Academy of Sciences 92 (9), 3717-3720, 1995
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
A Rolfs, I Kvietikova, M Gassmann, RH Wenger
Journal of Biological Chemistry 272 (32), 20055-20062, 1997
Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor
K Gradin, J McGuire, RH Wenger, I Kvietikova, ML Whitelaw, R Toftgård, ...
Molecular and cellular biology 16 (10), 5221-5231, 1996
The hypoxia-inducible factor-1α is a negative factor for tumor therapy
A Unruh, A Ressel, HG Mohamed, RS Johnson, R Nadrowitz, E Richter, ...
Oncogene 22 (21), 3213-3220, 2003
Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway
DP Stiehl, W Jelkmann, RH Wenger, T Hellwig-Bürgel
FEBS letters 512 (1-3), 157-162, 2002
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation
F Martin, T Linden, DM Katschinski, F Oehme, I Flamme, ...
Blood 105 (12), 4613-4619, 2005
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels: evidence for an autoregulatory oxygen-sensing system
DP Stiehl, R Wirthner, J Köditz, P Spielmann, G Camenisch, RH Wenger
Journal of Biological Chemistry 281 (33), 23482-23491, 2006
Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin
FT Ruschitzka, RH Wenger, T Stallmach, T Quaschning, C De Wit, ...
Proceedings of the National Academy of Sciences 97 (21), 11609-11613, 2000
Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect
A Carrière, MC Carmona, Y Fernandez, M Rigoulet, RH Wenger, ...
Journal of Biological Chemistry 279 (39), 40462-40469, 2004
Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1α
D Chilov, G Camenisch, I Kvietikova, U Ziegler, M Gassmann, RH Wenger
Journal of cell science 112 (8), 1203-1212, 1999
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site
I Kvietikova, RH Wenger, HH Marti, M Gassmann
Nucleic Acids Research 23 (22), 4542-4550, 1995
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
J Cosin-Roger, S Simmen, H Melhem, K Atrott, I Frey-Wagner, ...
Nature communications 8 (1), 98, 2017
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