The genomic and transcriptomic landscape of a HeLa cell line JJM Landry, PT Pyl, T Rausch, T Zichner, MM Tekkedil, AM Stütz, A Jauch, ... G3: Genes| Genomes| Genetics, 2013 | 540 | 2013 |
HEx: A heterologous expression platform for the discovery of fungal natural products CJB Harvey, M Tang, U Schlecht, J Horecka, CR Fischer, HC Lin, J Li, ... Science advances 4 (4), eaar5459, 2018 | 163 | 2018 |
Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies JP Lasserre, A Dautant, RS Aiyar, R Kucharczyk, A Glatigny, ... Disease models & mechanisms 8 (6), 509-526, 2015 | 140 | 2015 |
Multiplexed precision genome editing with trackable genomic barcodes in yeast KR Roy, JD Smith, SC Vonesch, G Lin, CS Tu, AR Lederer, A Chu, ... Nature Biotechnology, 2018 | 117 | 2018 |
Alternative polyadenylation diversifies post‐transcriptional regulation by selective RNA–protein interactions I Gupta, S Clauder‐Münster, B Klaus, AI Järvelin, RS Aiyar, V Benes, ... Molecular systems biology 10 (2), 719, 2014 | 109 | 2014 |
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products YF Li, KJS Tsai, CJB Harvey, JJ Li, BE Ary, EE Berlew, BL Boehman, ... Fungal Genetics and Biology 89, 18-28, 2016 | 104 | 2016 |
Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype J Gagneur, O Stegle, C Zhu, P Jakob, MM Tekkedil, RS Aiyar, AK Schuon, ... PLoS genetics 9 (9), e1003803, 2013 | 92 | 2013 |
A yeast-based assay identifies drugs active against human mitochondrial disorders E Couplan, RS Aiyar, R Kucharczyk, A Kabala, N Ezkurdia, J Gagneur, ... Proceedings of the National Academy of Sciences 108 (29), 11989-11994, 2011 | 91 | 2011 |
An Evaluation of High-Throughput Approaches to QTL Mapping in Saccharomyces cerevisiae S Wilkening, G Lin, ES Fritsch, MM Tekkedil, S Anders, R Kuehn, ... Genetics, genetics. 113.160291, 2013 | 87 | 2013 |
Experimental relocation of the mitochondrial ATP9 gene to the nucleus reveals forces underlying mitochondrial genome evolution M Bietenhader, A Martos, E Tetaud, RS Aiyar, CH Sellem, R Kucharczyk, ... PLoS genetics 8 (8), e1002876, 2012 | 52 | 2012 |
A method for high‐throughput production of sequence‐verified DNA libraries and strain collections JD Smith, U Schlecht, W Xu, S Suresh, J Horecka, MJ Proctor, RS Aiyar, ... Molecular Systems Biology 13 (2), 913, 2017 | 42 | 2017 |
A privacy-preserving solution for compressed storage and selective retrieval of genomic data Z Huang, E Ayday, H Lin, RS Aiyar, A Molyneaux, Z Xu, J Fellay, ... Genome research 26 (12), 1687-1696, 2016 | 37 | 2016 |
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders RS Aiyar, M Bohnert, S Duvezin-Caubet, C Voisset, J Gagneur, ES Fritsch, ... Nature communications 5, 5585, 2014 | 35 | 2014 |
Narrowing in on the causative defect of an intriguing X-linked myopathy with excessive autophagy BA Minassian, R Aiyar, S Alic, B Banwell, M Villanova, M Fardeau, ... Neurology 59 (4), 596-601, 2002 | 29 | 2002 |
Identification of mitochondrial disease genes through integrative analysis of multiple datasets RS Aiyar, J Gagneur, LM Steinmetz Methods 46 (4), 248-255, 2008 | 11 | 2008 |
Deep learning and automated Cell Painting reveal Parkinson's disease-specific signatures in primary patient fibroblasts L Schiff, B Migliori, Y Chen, D Carter, C Bonilla, J Hall, M Fan, E Tam, ... bioRxiv, 2020 | 4 | 2020 |
Perturbation and Rescue of the Yeast Mitochondrial System R Aiyar | | 2010 |
X-linked myopathy with excessive autophagy (XMEA): clinical spectrum, refined mapping and mutation screening. SA Alic, R Aiyar, V Juel, J Mandell, M Villanova, M Fardeau, SW Scherer, ... AMERICAN JOURNAL OF HUMAN GENETICS 69 (4), 538-538, 2001 | | 2001 |