DNAJC13 mutations in Parkinson disease C Vilariño-Güell, A Rajput, AJ Milnerwood, B Shah, C Szu-Tu, J Trinh, I Yu, ... Human molecular genetics 23 (7), 1794-1801, 2014 | 352 | 2014 |
Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p. D620N LN Munsie, AJ Milnerwood, P Seibler, DA Beccano-Kelly, I Tatarnikov, ... Human molecular genetics 24 (6), 1691-1703, 2015 | 152 | 2015 |
Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice DA Beccano-Kelly, N Kuhlmann, I Tatarnikov, M Volta, LN Munsie, ... Frontiers in cellular neuroscience 8, 301, 2014 | 129 | 2014 |
LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory DA Beccano-Kelly, M Volta, LN Munsie, SA Paschall, I Tatarnikov, K Co, ... Human molecular genetics 24 (5), 1336-1349, 2015 | 105 | 2015 |
Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice M Volta, DA Beccano-Kelly, SA Paschall, S Cataldi, SE MacIsaac, ... Elife 6, e28377, 2017 | 85 | 2017 |
Altered dopamine release and monoamine transporters in Vps35 p. D620N knock-in mice S Cataldi, J Follett, JD Fox, I Tatarnikov, C Kadgien, EK Gustavsson, ... npj Parkinson's Disease 4 (1), 27, 2018 | 64 | 2018 |
Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered … M Volta, S Cataldi, D Beccano-Kelly, L Munsie, I Tatarnikov, P Chou, ... Parkinsonism & Related Disorders 21 (10), 1156-1163, 2015 | 54 | 2015 |
The X-linked intellectual disability gene Zdhhc9 is essential for dendrite outgrowth and inhibitory synapse formation JJ Shimell, BS Shah, SM Cain, S Thouta, N Kuhlmann, I Tatarnikov, ... Cell reports 29 (8), 2422-2437. e8, 2019 | 47 | 2019 |
Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis A Bashir, ZA Abebe, KA McInnes, EB Button, I Tatarnikov, WH Cheng, ... Experimental neurology 324, 113116, 2020 | 37 | 2020 |
DNAJC13 p. Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of sorting nexin 1 J Follett, JD Fox, EK Gustavsson, C Kadgien, LN Munsie, LP Cao, ... Neuroscience Letters 706, 114-122, 2019 | 8 | 2019 |
MONI can find k-MEMs I Tatarnikov, AS Farahani, S Kashgouli, T Gagie arXiv preprint arXiv:2202.05085, 2022 | 4 | 2022 |
Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p. D620N knock-in mice M Bu, J Follett, I Deng, I Tatarnikov, S Wall, D Guenther, M Maczis, ... npj Parkinson's Disease 9 (1), 167, 2023 | 1 | 2023 |
Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine dynamics in VPS35 p. D620N knock-in mice M Bu, J Follett, I Tatarnikov, SC Wall, DT Guenther, IB Deng, G Wimsatt, ... bioRxiv, 2023.05. 14.540654, 2023 | 1 | 2023 |
In vitro and ex vivo exploration of knock-in mouse models harboring mutations linked to late onset Parkinson’s disease I Tatarnikov University of British Columbia, 2020 | | 2020 |