| Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution H Mundhada, JM Seoane, K Schneider, A Koza, HB Christensen, T Klein, ... Metabolic Engineering 39, 141-150, 2017 | 140 | 2017 |
| Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway KR Kildegaard, NB Jensen, K Schneider, E Czarnotta, E Özdemir, T Klein, ... Microbial cell factories 15 (1), 1-13, 2016 | 129 | 2016 |
| A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off‐gas T Klein, K Schneider, E Heinzle Biotechnology and bioengineering 110 (2), 535-542, 2013 | 51 | 2013 |
| Combining mechanistic and data‐driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed‐batch CHO process D Zalai, K Koczka, L Párta, P Wechselberger, T Klein, C Herwig Biotechnology progress 31 (6), 1657-1668, 2015 | 48 | 2015 |
| Elevated pCO2 affects the lactate metabolic shift in CHO cell culture processes M Brunner, P Doppler, T Klein, C Herwig, J Fricke Engineering in Life Sciences 18 (3), 204-214, 2018 | 45 | 2018 |
| Overcoming the metabolic burden of protein secretion in Schizosaccharomyces pombe–A quantitative approach using 13 C-based metabolic flux analysis T Klein, S Lange, N Wilhelm, M Bureik, TH Yang, E Heinzle, K Schneider Metabolic engineering 21, 34-45, 2014 | 44 | 2014 |
| Immobilization of cysteine-tagged proteins on electrode surfaces by thiol–ene click chemistry L Zhang, N Vilà, T Klein, GW Kohring, I Mazurenko, A Walcarius, ... ACS Applied Materials & Interfaces 8 (27), 17591-17598, 2016 | 43 | 2016 |
| Engineering the supply chain for protein production/secretion in yeasts and mammalian cells T Klein, J Niklas, E Heinzle Journal of Industrial Microbiology and Biotechnology 42 (3), 453-464, 2015 | 31 | 2015 |
| Quantification of cell lysis during CHO bioprocesses: Impact on cell count, growth kinetics and productivity T Klein, N Heinzel, P Kroll, M Brunner, C Herwig, L Neutsch J Biotechnol, 2015 | 30 | 2015 |
| Introducing substrate limitations to overcome catabolite repression in a protease producing Bacillus licheniformis strain using membrane‐based fed‐batch shake … T Habicher, A John, N Scholl, A Daub, T Klein, P Philip, J Büchs Biotechnology and Bioengineering 116 (6), 1326-1340, 2019 | 22 | 2019 |
| Exploring small-scale chemostats to scale up microbial processes: 3-hydroxypropionic acid production in S. cerevisiae AV Lis, K Schneider, J Weber, JD Keasling, MK Jensen, T Klein Microbial cell factories 18 (1), 1-11, 2019 | 19 | 2019 |
| Media photo‐degradation in pharmaceutical biotechnology–impact of ambient light on media quality, cell physiology, and IgG production in CHO cultures L Neutsch, P Kroll, M Brunner, A Pansy, M Kovar, C Herwig, T Klein Journal of Chemical Technology & Biotechnology 93 (8), 2141-2151, 2018 | 17 | 2018 |
| Ex situ online monitoring: application, challenges and opportunities for biopharmaceuticals processes P Kroll, P Sagmeister, W Reichelt, L Neutsch, T Klein, C Herwig Pharmaceutical Bioprocessing 2 (3), 285-300, 2014 | 17 | 2014 |
| Metabolic fluxes in Schizosaccharomyces pombe grown on glucose and mixtures of glycerol and acetate T Klein, E Heinzle, K Schneider Applied microbiology and biotechnology 97 (11), 5013-5026, 2013 | 13 | 2013 |
| Establishing a Fed‐Batch Process for Protease Expression with Bacillus licheniformis in Polymer‐Based Controlled‐Release Microtiter Plates T Habicher, EKA Rauls, F Egidi, T Keil, T Klein, A Daub, J Büchs Biotechnology journal 15 (2), 1900088, 2020 | 12 | 2020 |
| Glucose‐containing polymer rings enable fed‐batch operation in microtiter plates with parallel online measurement of scattered light, fluorescence, dissolved oxygen tension, and pH T Habicher, V Czotscher, T Klein, A Daub, T Keil, J Büchs Biotechnology and Bioengineering 116 (9), 2250-2262, 2019 | 11 | 2019 |
| Comparative proteome analysis in Schizosaccharomyces pombe identifies metabolic targets to improve protein production and secretion CW Hung, T Klein, L Cassidy, D Linke, S Lange, U Anders, M Bureik, ... Molecular & Cellular Proteomics 15 (10), 3090-3106, 2016 | 9 | 2016 |
| Sol-gel Approaches for Elaboration of Polyol Dehydrogenase-Based Bioelectrodes V Urbanova, GW Kohring, T Klein, Z Wang, O Mert, M Emrullahoglu, ... Zeitschrift für Physikalische Chemie 227 (5), 667-689, 2013 | 8 | 2013 |
| Acetate‐containing substrate mixtures improve recombinant protein secretion in Schizosaccharomyces pombe T Klein, E Heinzle, K Schneider Engineering in Life Sciences 15 (4), 437-442, 2015 | 3 | 2015 |
| Screening for optimal protease producing Bacillus licheniformis strains with polymer-based controlled-release fed-batch microtiter plates T Habicher, T Klein, J Becker, A Daub, J Büchs Microbial Cell Factories 20 (1), 1-12, 2021 | 1 | 2021 |
Konstantin SchneiderBASF SEVerified email at basf.com
