Robert Schierwagen
Robert Schierwagen
Department of Internal Medicine I, Goethe University Frankfurt
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Angiotensin‐II type 1 receptor‐mediated Janus kinase 2 activation induces liver fibrosis
M Granzow, R Schierwagen, S Klein, B Kowallick, S Huss, M Linhart, ...
Hepatology 60 (1), 334-348, 2014
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis
L Verbeke, I Mannaerts, R Schierwagen, O Govaere, S Klein, ...
Scientific reports 6 (1), 1-12, 2016
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats
S Klein, J Klösel, R Schierwagen, C Körner, M Granzow, S Huss, ...
Laboratory investigation 92 (10), 1440-1450, 2012
HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects
S Klein, MM Van Beuge, M Granzow, L Beljaars, R Schierwagen, S Kilic, ...
Journal of hepatology 57 (6), 1220-1227, 2012
Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor‐deficient mice and decreased in CB1 receptor …
J Trebicka, I Racz, SV Siegmund, E Cara, M Granzow, R Schierwagen, ...
Liver International 31 (6), 860-870, 2011
Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis
R Schierwagen, L Maybüchen, S Zimmer, K Hittatiya, C Bäck, S Klein, ...
Scientific reports 5, 12931, 2015
Activation of the Mas receptor by angiotensin-(1–7) in the renin–angiotensin system mediates mesenteric vasodilatation in cirrhosis
JA Grace, S Klein, CB Herath, M Granzow, R Schierwagen, N Masing, ...
Gastroenterology 145 (4), 874-884. e5, 2013
Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis
S Klein, J Rick, J Lehmann, R Schierwagen, IG Schierwagen, L Verbeke, ...
Gut 66 (1), 145-155, 2017
Circulating microRNAs as a marker for liver injury in human immunodeficiency virus patients
E Anadol, R Schierwagen, N Elfimova, K Tack, C Schwarze‐Zander, ...
Hepatology 61 (1), 46-55, 2015
Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection
M Beyer, Z Abdullah, JM Chemnitz, D Maisel, J Sander, C Lehmann, ...
Nature immunology 17 (5), 593-603, 2016
Circulating microbiome in blood of different circulatory compartments
R Schierwagen, C Alvarez-Silva, MSA Madsen, CC Kolbe, C Meyer, ...
Gut 68 (3), 578-580, 2019
Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats
R Schierwagen, S Klein, DJ Leeming, M Granzow, MJ Nielsen, ...
Frontiers in physiology 4, 195, 2013
Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality
C Jansen, P Möller, C Meyer, CC Kolbe, C Bogs, A Pohlmann, ...
Hepatology 67 (4), 1472-1484, 2018
Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal …
FE Uschner, G Ranabhat, SS Choi, M Granzow, S Klein, R Schierwagen, ...
Scientific reports 5, 14573, 2015
Rationale for the use of statins in liver disease
R Schierwagen, FE Uschner, F Magdaleno, S Klein, J Trebicka
American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (5 …, 2017
Addressing profiles of systemic inflammation across the different clinical phenotypes of acutely decompensated cirrhosis
J Trebicka, A Amoros, C Pitarch, E Titos, J Alcaraz-Quiles, R Schierwagen, ...
Frontiers in immunology 10, 476, 2019
Statins improve NASH via inhibition of RhoA and Ras
R Schierwagen, L Maybüchen, K Hittatiya, S Klein, FE Uschner, TT Braga, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016
Statins, Rho GTPases and KLF2: new mechanistic insight into liver fibrosis and portal hypertension
J Trebicka, R Schierwagen
Gut 64 (9), 1349-1350, 2015
PRO-C3-levels in patients with HIV/HCV-Co-infection reflect fibrosis stage and degree of portal hypertension
C Jansen, DJ Leeming, M Mandorfer, I Byrjalsen, R Schierwagen, ...
PloS one 9 (9), e108544, 2014
Quantification of liver fibrosis at T1 and T2 mapping with extracellular volume fraction MRI: preclinical results
JA Luetkens, S Klein, F Träber, FC Schmeel, AM Sprinkart, DLR Kuetting, ...
Radiology 288 (3), 748-754, 2018
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