Bruck Taddese
Bruck Taddese
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Five computational developability guidelines for therapeutic antibody profiling
MIJ Raybould, C Marks, K Krawczyk, B Taddese, J Nowak, AP Lewis, ...
Proceedings of the National Academy of Sciences, 201810576, 2019
Do plants contain g protein-coupled receptors?
B Taddese, GJG Upton, GR Bailey, SRD Jordan, NY Abdulla, PJ Reeves, ...
Plant physiology 164 (1), 287-307, 2014
Bioinformatics and molecular modelling approaches to GPCR oligomerization
LM Simpson, B Taddese, ID Wall, CA Reynolds
Current opinion in pharmacology 10 (1), 30-37, 2010
Thera-SAbDab: the Therapeutic Structural Antibody Database
MIJ Raybould, C Marks, AP Lewis, J Shi, A Bujotzek, B Taddese, ...
Nucleic Acids Research 48 (D1), D383-D388, 2020
Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
S Vohra, B Taddese, AC Conner, DR Poyner, DL Hay, J Barwell, ...
Journal of The Royal Society Interface 10 (79), 20120846, 2013
The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach
MJ Woolley, HA Watkins, B Taddese, ZG Karakullukcu, J Barwell, ...
Journal of The Royal Society Interface 10 (88), 20130589, 2013
Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain
WA Williams, JE Linley, CA Jones, Y Shibata, A Snijder, J Button, ...
Pain 160 (9), 1989-2003, 2019
DLAB-Deep learning methods for structure-based virtual screening of antibodies
C Schneider, A Buchanan, B Taddese, CM Deane
bioRxiv, 2021
Ab-Ligity: Identifying sequence-dissimilar antibodies that bind to the same epitope
WK Wong, SA Robinson, A Bujotzek, G Georges, AP Lewis, J Shi, ...
BioRxiv, 2020
The activation of the CGRP receptor
J Barwell, M Wheatley, AC Conner, B Taddese, S Vohra, CA Reynolds, ...
Biochemical Society Transactions 41 (1), 180-184, 2013
G-protein-coupled receptor dynamics: dimerization and activation models compared with experiment
B Taddese, LM Simpson, ID Wall, FE Blaney, NJ Kidley, HSX Clark, ...
Biochemical Society Transactions 40 (2), 394-399, 2012
SCALOP: sequence-based antibody canonical loop structure annotation
WK Wong, G Georges, F Ros, S Kelm, AP Lewis, B Taddese, J Leem, ...
Bioinformatics, 2018
Modeling active GPCR conformations
B Taddese, LM Simpson, ID Wall, FE Blaney, CA Reynolds
Methods in enzymology 522, 21-35, 2013
Evolution of chemokine receptors is driven by mutations in the sodium binding site
B Taddese, M Deniaud, A Garnier, A Tiss, H Guissouma, H Abdi, ...
PLoS computational biology 14 (6), e1006209, 2018
Molecular insights into the transmembrane domain of the thyrotropin receptor
V Chantreau, B Taddese, M Munier, L Gourdin, D Henrion, P Rodien, ...
PloS one 10 (11), e0142250, 2015
Deciphering collaborative sidechain motions in proteins during molecular dynamics simulations
B Taddese, A Garnier, H Abdi, D Henrion, M Chabbert
Scientific reports 10 (1), 1-14, 2020
Identifying subset errors in multiple sequence alignments
A Roy, B Taddese, S Vohra, PK Thimmaraju, CJR Illingworth, ...
Journal of Biomolecular Structure and Dynamics 32 (3), 364-371, 2014
E-Biothon: an experimental platform for BioInformatics
M Daydé, B Depardon, A Franc, JF Gibrat, R Guilllier, Y Karami, F Sutter, ...
2015 Computer Science and Information Technologies (CSIT), 1-4, 2015
Bios2cor: an R package integrating dynamic and evolutionary correlations to identify functionally important residues in proteins
B Taddese, A Garnier, M Deniaud, D Henrion, M Chabbert
Bioinformatics, 2021
Co-Variation Approaches to the Evolution of Protein Families
J Pelé, B Taddese, M Deniaud, A Garnier, D Henrion
Adv Tech Biol Med 5 (250), 2379-1764.1000250, 2017
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