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David Nguyen
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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ...
Nature biotechnology 26 (5), 561-569, 2008
14082008
Reprogramming human T cell function and specificity with non-viral genome targeting
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
7492018
Polymeric materials for gene delivery and DNA vaccination
DN Nguyen, JJ Green, JM Chan, R Langer, DG Anderson
Advanced Materials 21 (8), 847-867, 2009
3362009
Molecularly engineered poly (ortho ester) microspheres for enhanced delivery of DNA vaccines
C Wang, Q Ge, D Ting, D Nguyen, HR Shen, J Chen, HN Eisen, J Heller, ...
Nature Materials 3 (3), 190-196, 2004
3112004
Test performance evaluation of SARS-CoV-2 serological assays
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174, 2020
2642020
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174-1183, 2020
2442020
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ...
Nature Biotechnology 38 (1), 44-49, 2020
2182020
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
DL Ng, GM Goldgof, BR Shy, AG Levine, J Balcerek, SP Bapat, J Prostko, ...
Nature Communications 11 (1), 1-7, 2020
1942020
Pooled knockin targeting for genome engineering of cellular immunotherapies
TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ...
Cell 181 (3), 728-744. e21, 2020
1622020
Small molecule end group of linear polymer determines cell-type gene delivery efficacy
J Sunshine, JJ Green, KP Mahon, F Yang, AA Eltoukhy, DN Nguyen, ...
Advanced materials (Deerfield Beach, Fla.) 21 (48), 4947, 2009
1242009
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ...
Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012
1232012
Drug delivery–mediated control of RNA immunostimulation
DN Nguyen, SCY Chen, J Lu, M Goldberg, P Kim, A Sprague, ...
Molecular Therapy 17 (9), 1555-1562, 2009
1052009
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering
JR Hamilton, CA Tsuchida, DN Nguyen, BR Shy, ER McGarrigle, ...
Cell reports 35 (9), 2021
1032021
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
B Wienert, DN Nguyen, A Guenther, SJ Feng, MN Locke, SK Wyman, ...
Nature communications 11 (1), 2109, 2020
972020
Modulation of the immune response
DHN Nguyen, DG Anderson, RS Langer, KP Mahon
US Patent App. 13/126,260, 2012
852012
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ...
Nature biotechnology 41 (4), 521-531, 2023
822023
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood
DL Ng, AC Granados, YA Santos, V Servellita, GM Goldgof, C Meydan, ...
Science advances 7 (6), eabe5984, 2021
802021
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment
Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ...
Science advances 7 (17), eabg4755, 2021
782021
A novel high‐throughput cell‐based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery
DN Nguyen, P Kim, L Martínez‐Sobrido, B Beitzel, A García‐Sastre, ...
Biotechnology and bioengineering 103 (4), 664-675, 2009
772009
Enhancement of poly (orthoester) microspheres for DNA vaccine delivery by blending with poly (ethylenimine)
DN Nguyen, SS Raghavan, LM Tashima, EC Lin, SJ Fredette, RS Langer, ...
Biomaterials 29 (18), 2783-2793, 2008
712008
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