The role of enhancers in cancer I Sur, J Taipale Nature Reviews Cancer 16 (8), 483-493, 2016 | 383 | 2016 |
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ... Cell 154 (4), 801-813, 2013 | 383 | 2013 |
Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 236 | 2012 |
Single-cell transcriptomics of traced epidermal and hair follicle stem cells reveals rapid adaptations during wound healing S Joost, T Jacob, X Sun, K Annusver, G La Manno, I Sur, M Kasper Cell reports 25 (3), 585-597. e7, 2018 | 154 | 2018 |
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition MH Lind, B Rozell, RPA Wallin, M van Hogerlinden, HG Ljunggren, ... Proceedings of the National Academy of Sciences 101 (14), 4972-4977, 2004 | 149 | 2004 |
Lessons from functional analysis of genome-wide association studies I Sur, S Tuupanen, T Whitington, LA Aaltonen, J Taipale Cancer research 73 (14), 4180-4184, 2013 | 76 | 2013 |
Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis I Sur, B Rozell, V Jaks, A Bergström, R Toftgård Journal of cell science 119 (17), 3593-3601, 2006 | 70 | 2006 |
The two-faced NF-κB in the skin I Sur, M Ulvmar, R Toftgård International reviews of immunology 27 (4), 205-223, 2008 | 67 | 2008 |
Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth K Dave, I Sur, J Yan, J Zhang, E Kaasinen, F Zhong, L Blaas, X Li, ... Elife 6, e23382, 2017 | 59 | 2017 |
Human Krüppel-like factor5/KLF5: Synergy with NF-κB/Rel factors and expression in human skin and hair follicles I Sur, AB Undén, R Toftgård European journal of cell biology 81 (6), 323-334, 2002 | 51 | 2002 |
Nitric oxide synthase inhibitor and IL-18 enhance the anti-tumor immune response of rats carrying an intrahepatic colon carcinoma P Hegardt, B Widegren, L Li, B SjoÈgren, C Kjellman, I Sur, H Sjögren Cancer Immunology, Immunotherapy 50, 491-501, 2001 | 45 | 2001 |
A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility B Wei, A Jolma, B Sahu, LM Orre, F Zhong, F Zhu, T Kivioja, I Sur, J Lehtiö, ... Nature biotechnology 36 (6), 521-529, 2018 | 35 | 2018 |
Analysis of PFK3—A gene involved in particulate phosphofructokinase synthesis reveals additional functions of TPS2 in Saccharomyces cerevisiae IP Sur, Z Lobo, PK Maitra Yeast 10 (2), 199-209, 1994 | 21 | 1994 |
Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element S Maijgren, I Sur, M Nilsson, R Toftgård Archives of dermatological research 295, 482-489, 2004 | 19 | 2004 |
Timed NF-κB inhibition in skin reveals dual independent effects on development of HED/EDA and chronic inflammation MH Ulvmar, I Sur, S Mémet, R Toftgård Journal of investigative dermatology 129 (11), 2584-2593, 2009 | 15 | 2009 |
Kruppel-like factors 4 and 5: unity in diversity I Sur Current genomics 10 (8), 594-603, 2009 | 11 | 2009 |
Inhibition of NF-κB signaling interferes with phorbol ester-induced growth arrest of keratinocytes in a TNFR1-independent manner I Sur, M Ulvmar, R Jungedal, R Toftgård Journal of Receptors and Signal Transduction 29 (1), 44-51, 2009 | 4 | 2009 |
Repression of transcription by HoxC11 upon phorbol ester stimulation IP Sur, R Toftgård Molecular Cell Biology Research Communications 3 (6), 367-373, 2000 | 3 | 2000 |
Severe liver disease resembling PSC in mice with K5-Cre mediated deletion of Krüppel-like factor 5 (Klf5) Å Bergström, M Gerling, N Van Hul, C Fernández Moro, B Rozell, ... Transgenic Research 30 (5), 701-707, 2021 | 2 | 2021 |
Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer D Afenteva, R Yu, A Rajavuori, M Salvadores, IM Launonen, K Lavikka, ... bioRxiv, 2024.03. 28.587131, 2024 | | 2024 |