Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease D Morgan, DM Diamond, PE Gottschall, KE Ugen, C Dickey, J Hardy, ... Nature 408 (6815), 982-985, 2000 | 2134 | 2000 |
Increased amyloid-β42 (43) in brains of mice expressing mutant presenilin 1 K Duff, C Eckman, C Zehr, X Yu, CM Prada, J Perez-Tur, M Hutton, L Buee, ... Nature 383 (6602), 710-713, 1996 | 2044 | 1996 |
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes L Holcomb, MN Gordon, E McGowan, X Yu, S Benkovic, P Jantzen, ... Nature medicine 4 (1), 97-100, 1998 | 1721 | 1998 |
Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model JA Joseph, G Arendash, M Gordon, D Diamond, B Shukitt-Hale, D Morgan, ... Nutritional neuroscience 6 (3), 153-162, 2003 | 519 | 2003 |
Passive immunotherapy against Aβ in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and … DM Wilcock, A Rojiani, A Rosenthal, S Subbarao, MJ Freeman, ... Journal of neuroinflammation 1, 1-11, 2004 | 481 | 2004 |
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits LA Holcomb, MN Gordon, P Jantzen, K Hsiao, K Duff, D Morgan Behavior genetics 29, 177-185, 1999 | 467 | 1999 |
Microglial activation and β-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 … PT Jantzen, KE Connor, G DiCarlo, GL Wenk, JL Wallace, AM Rojiani, ... Journal of Neuroscience 22 (6), 2246-2254, 2002 | 462 | 2002 |
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes GW Arendash, DL King, MN Gordon, D Morgan, JM Hatcher, CE Hope, ... Brain research 891 (1-2), 42-53, 2001 | 442 | 2001 |
Caloric restriction attenuates Aβ-deposition in Alzheimer transgenic models NV Patel, MN Gordon, KE Connor, RA Good, RW Engelman, J Mason, ... Neurobiology of aging 26 (7), 995-1000, 2005 | 416 | 2005 |
Intracranially administered anti-Αβ antibodies reduce β-amyloid deposition by mechanisms both independent of and associated with microglial activation DM Wilcock, G DiCarlo, D Henderson, J Jackson, K Clarke, KE Ugen, ... Journal of Neuroscience 23 (9), 3745-3751, 2003 | 387 | 2003 |
Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition DM Wilcock, A Rojiani, A Rosenthal, G Levkowitz, S Subbarao, J Alamed, ... Journal of Neuroscience 24 (27), 6144-6151, 2004 | 379 | 2004 |
LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ... Journal of neuroinflammation 7, 1-16, 2010 | 306 | 2010 |
Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice J Alamed, DM Wilcock, DM Diamond, MN Gordon, D Morgan Nature protocols 1 (4), 1671-1679, 2006 | 304 | 2006 |
Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein+ presenilin-1 transgenic mice CA Dickey, JF Loring, J Montgomery, MN Gordon, PS Eastman, D Morgan Journal of Neuroscience 23 (12), 5219-5226, 2003 | 302 | 2003 |
Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+ APP mouse MN Gordon, LA Holcomb, PT Jantzen, G DiCarlo, D Wilcock, KW Boyett, ... Experimental neurology 173 (2), 183-195, 2002 | 299 | 2002 |
Intrahippocampal LPS injections reduce Aβ load in APP+ PS1 transgenic mice G DiCarlo, D Wilcock, D Henderson, M Gordon, D Morgan Neurobiology of aging 22 (6), 1007-1012, 2001 | 297 | 2001 |
Correlation between cognitive deficits and Aβ deposits in transgenic APP+ PS1 mice MN Gordon, DL King, DM Diamond, PT Jantzen, KV Boyett, CE Hope, ... Neurobiology of aging 22 (3), 377-385, 2001 | 255 | 2001 |
Microglial activation facilitates Aβ plaque removal following intracranial anti-Aβ antibody administration DM Wilcock, SK Munireddy, A Rosenthal, KE Ugen, MN Gordon, ... Neurobiology of disease 15 (1), 11-20, 2004 | 254 | 2004 |
Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics D Morgan, MN Gordon, J Tan, D Wilcock, AM Rojiani Journal of Neuropathology & Experimental Neurology 64 (9), 743-753, 2005 | 239 | 2005 |
Deglycosylated anti-amyloid-β antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein … DM Wilcock, J Alamed, PE Gottschall, J Grimm, A Rosenthal, J Pons, ... Journal of Neuroscience 26 (20), 5340-5346, 2006 | 199 | 2006 |