| Distinct cortical and striatal actions of a β-arrestin–biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties NM Urs, SM Gee, TF Pack, JD McCorvy, T Evron, JC Snyder, X Yang, ... Proceedings of the National Academy of Sciences 113 (50), E8178-E8186, 2016 | 137 | 2016 |
| New concepts in dopamine D2 receptor biased signaling and implications for schizophrenia therapy NM Urs, SM Peterson, MG Caron Biological psychiatry 81 (1), 78-85, 2017 | 126 | 2017 |
| A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice NM Urs, TL Daigle, MG Caron Neuropsychopharmacology 36 (3), 551-558, 2011 | 119 | 2011 |
| Targeting β-arrestin2 in the treatment of l-DOPA–induced dyskinesia in Parkinson’s disease NM Urs, S Bido, SM Peterson, TL Daigle, CE Bass, RR Gainetdinov, ... Proceedings of the National Academy of Sciences 112 (19), E2517-E2526, 2015 | 112 | 2015 |
| Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action NM Urs, JC Snyder, JPR Jacobsen, SM Peterson, MG Caron Proceedings of the National Academy of Sciences 109 (50), 20732-20737, 2012 | 104 | 2012 |
| Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor SM Peterson, TF Pack, AD Wilkins, NM Urs, DJ Urban, CE Bass, ... Proceedings of the National Academy of Sciences 112 (22), 7097-7102, 2015 | 101 | 2015 |
| β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions L Zhu, J Almaça, PK Dadi, H Hong, W Sakamoto, M Rossi, RJ Lee, ... Nature communications 8 (1), 14295, 2017 | 86 | 2017 |
| G protein and β-arrestin signaling bias at the ghrelin receptor T Evron, SM Peterson, NM Urs, Y Bai, LK Rochelle, MG Caron, LS Barak Journal of Biological Chemistry 289 (48), 33442-33455, 2014 | 75 | 2014 |
| D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice IO Medvedev, AJ Ramsey, ST Masoud, MK Bermejo, N Urs, TD Sotnikova, ... Journal of Neuroscience 33 (46), 18125-18133, 2013 | 75 | 2013 |
| A requirement for membrane cholesterol in the β-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors NM Urs, KT Jones, PD Salo, JE Severin, JA Trejo, H Radhakrishna Journal of cell science 118 (22), 5291-5304, 2005 | 67 | 2005 |
| Hepatic β-arrestin 2 is essential for maintaining euglycemia L Zhu, M Rossi, Y Cui, RJ Lee, W Sakamoto, NA Perry, NM Urs, ... The Journal of clinical investigation 127 (8), 2941-2945, 2017 | 44 | 2017 |
| ML314: a biased neurotensin receptor ligand for methamphetamine abuse LS Barak, Y Bai, S Peterson, T Evron, NM Urs, S Peddibhotla, MP Hedrick, ... ACS chemical biology 11 (7), 1880-1890, 2016 | 35 | 2016 |
| Integrated approaches to understanding antipsychotic drug action at GPCRs NM Urs, PJ Nicholls, MG Caron Current opinion in cell biology 27, 56-62, 2014 | 30 | 2014 |
| Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission TL Daigle, MJ Ferris, RR Gainetdinov, TD Sotnikova, NM Urs, SR Jones, ... Neuropsychopharmacology 39 (10), 2450-2462, 2014 | 25 | 2014 |
| Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo LM Vecchio, P Sullivan, AR Dunn, MK Bermejo, R Fu, ST Masoud, ... Journal of neurochemistry 158 (4), 960-979, 2021 | 24 | 2021 |
| Different mechanisms regulate lysophosphatidic acid (LPA)-dependent versus phorbol ester-dependent internalization of the LPA1 receptor NM Urs, AP Kowalczyk, H Radhakrishna Journal of biological chemistry 283 (9), 5249-5257, 2008 | 24 | 2008 |
| Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons SP Pydi, Z Cui, Z He, LF Barella, J Pham, Y Cui, DJ Oberlin, HE Egritag, ... Science advances 6 (23), eaaz1341, 2020 | 21 | 2020 |
| Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept JPR Jacobsen, A Oh, R Bangle, WL Roberts, EL Royer, N Modesto, ... Neuropsychopharmacology 44 (12), 2082-2090, 2019 | 21 | 2019 |
| α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability A Dagra, DR Miller, M Lin, A Gopinath, F Shaerzadeh, S Harris, ... npj Parkinson's Disease 7 (1), 76, 2021 | 20 | 2021 |
| Deletion of glycogen synthase kinase-3β in D2 receptor–positive neurons ameliorates cognitive impairment via NMDA receptor–dependent synaptic plasticity YC Li, P Panikker, B Xing, SS Yang, C Alexandropoulos, EP McEachern, ... Biological psychiatry 87 (8), 745-755, 2020 | 19 | 2020 |
Sean PetersonGraduate Student, Duke UniversityVerified email at duke.edu
