Jerome Lugrin
Jerome Lugrin
Lausanne University Hospital, Service of Intensive Care Medicine & Service of Thoracic Surgery
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The role of oxidative stress during inflammatory processes
J Lugrin, N Rosenblatt-Velin, R Parapanov, L Liaudet
Biological chemistry 395 (2), 203-230, 2014
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
T Roger, J Lugrin, D Le Roy, G Goy, M Mombelli, T Koessler, XC Ding, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1205-1217, 2011
The AIM 2 inflammasome: sensor of pathogens and cellular perturbations
J Lugrin, F Martinon
Immunological reviews 281 (1), 99-114, 2018
Cutting edge: IL-1α is a crucial danger signal triggering acute myocardial inflammation during myocardial infarction
J Lugrin, R Parapanov, N Rosenblatt-Velin, S Rignault-Clerc, F Feihl, ...
The Journal of Immunology 194 (2), 499-503, 2015
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity
A Di Micco, G Frera, J Lugrin, Y Jamilloux, ET Hsu, A Tardivel, ...
Proceedings of the National Academy of Sciences 113 (32), E4671-E4680, 2016
Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation
M Castelblanco, J Lugrin, D Ehirchiou, S Nasi, I Ishii, A So, F Martinon, ...
Journal of Biological Chemistry 293 (7), 2546-2557, 2018
Histone deacetylase inhibitors impair antibacterial defenses of macrophages
M Mombelli, J Lugrin, I Rubino, AL Chanson, M Giddey, T Calandra, ...
Journal of Infectious Diseases 204 (9), 1367-1374, 2011
The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock
J Lugrin, E Ciarlo, A Santos, G Grandmaison, I Dos Santos, D Le Roy, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (6), 1498-1510, 2013
Periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome is associated with a CARD8 variant unable to bind the NLRP3 inflammasome
MS Cheung, K Theodoropoulou, J Lugrin, F Martinon, N Busso, M Hofer
The Journal of Immunology 198 (5), 2063-2069, 2017
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation
J Lugrin, XC Ding, D Le Roy, AL Chanson, FCGJ Sweep, T Calandra, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (11), 1749-1758, 2009
Sirtuin 2 deficiency increases bacterial phagocytosis by macrophages and protects from chronic staphylococcal infection
E Ciarlo, T Heinonen, C Théroude, J Herderschee, M Mombelli, J Lugrin, ...
Frontiers in immunology 8, 1037, 2017
Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia
C Francioli, X Wang, R Parapanov, E Abdelnour, J Lugrin, F Gronchi, ...
PLoS One 12 (3), e0173916, 2017
Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections
E Ciarlo, T Heinonen, J Lugrin, H Acha-Orbea, D Le Roy, J Auwerx, ...
Scientific reports 7 (1), 3853, 2017
Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse
R Parapanov, J Lugrin, N Rosenblatt-Velin, F Feihl, B Waeber, G Milano, ...
Clinical Science 129 (2), 187-198, 2015
Detection of ASC oligomerization by western blotting
J Lugrin, F Martinon
Bio-protocol 7 (10), e2292-e2292, 2017
Murine myocardial infarction model using permanent ligation of left anterior descending coronary artery
J Lugrin, R Parapanov, T Krueger, L Liaudet
JoVE (Journal of Visualized Experiments), e59591, 2019
Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation
X Wang, R Parapanov, A Debonneville, Y Wang, E Abdelnour-Berchtold, ...
American Journal of Transplantation 20 (4), 967-976, 2020
Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation
A Hasenauer, B Bédat, R Parapanov, J Lugrin, A Debonneville, ...
The Journal of Heart and Lung Transplantation 40 (9), 905-916, 2021
The systemic deletion of interleukin-1α reduces myocardial inflammation and attenuates ventricular remodeling in murine myocardial infarction
J Lugrin, R Parapanov, G Milano, S Cavin, A Debonneville, T Krueger, ...
Scientific Reports 13 (1), 4006, 2023
Therapeutic reconditioning of damaged lungs by transient heat stress during ex vivo lung perfusion
A Ojanguren, R Parapanov, A Debonneville, J Lugrin, C Szabo, ...
American Journal of Transplantation 23 (8), 1130-1144, 2023
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