| TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ... Nature 554 (7693), 544-548, 2018 | 4337 | 2018 |
| Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-18, 2007 | 2314 | 2007 |
| Spontaneous mutation accumulation studies in evolutionary genetics DL Halligan, PD Keightley Annual Review of Ecology, Evolution, and Systematics 40 (1), 151-172, 2009 | 488 | 2009 |
| Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila C Haag-Liautard, M Dorris, X Maside, S Macaskill, DL Halligan, ... Nature 445 (7123), 82-85, 2007 | 444 | 2007 |
| Natural selection drives extremely rapid evolution in antiviral RNAi genes DJ Obbard, FM Jiggins, DL Halligan, TJ Little Current biology 16 (6), 580-585, 2006 | 335 | 2006 |
| Estimation of the Spontaneous Mutation Rate per Nucleotide Site in a Drosophila melanogaster Full-Sib Family PD Keightley, RW Ness, DL Halligan, PR Haddrill Genetics 196 (1), 313-320, 2014 | 305 | 2014 |
| Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison DL Halligan, PD Keightley Genome research 16 (7), 875-884, 2006 | 285 | 2006 |
| Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content PR Haddrill, B Charlesworth, DL Halligan, P Andolfatto Genome biology 6, 1-8, 2005 | 205 | 2005 |
| Survival prediction in mesothelioma using a scalable Lasso regression model: instructions for use and initial performance using clinical predictors AC Kidd, M McGettrick, S Tsim, DL Halligan, M Bylesjo, KG Blyth BMJ open respiratory research 5 (1), 2018 | 185 | 2018 |
| Reduced efficacy of selection in regions of the Drosophila genome that lack crossing over PR Haddrill, DL Halligan, D Tomaras, B Charlesworth Genome biology 8, 1-9, 2007 | 175 | 2007 |
| The Relation between Recombination Rate and Patterns of Molecular Evolution and Variation in Drosophila melanogaster JL Campos, DL Halligan, PR Haddrill, B Charlesworth Molecular biology and evolution 31 (4), 1010-1028, 2014 | 158 | 2014 |
| Evidence for pervasive adaptive protein evolution in wild mice DL Halligan, F Oliver, A Eyre-Walker, B Harr, PD Keightley PLoS genetics 6 (1), e1000825, 2010 | 153 | 2010 |
| Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila DL Halligan, A Eyre-Walker, P Andolfatto, PD Keightley Genome research 14 (2), 273-279, 2004 | 132 | 2004 |
| Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents DL Halligan, A Kousathanas, RW Ness, B Harr, L Eöry, TM Keane, ... PLoS genetics 9 (12), e1003995, 2013 | 123 | 2013 |
| Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes L Eőry, DL Halligan, PD Keightley Molecular Biology and Evolution 27 (1), 177-192, 2010 | 111 | 2010 |
| Comprehensive profiling of poor-risk paired primary and recurrent triple-negative breast cancers reveals immune phenotype shifts KE Hutchinson, SE Yost, CW Chang, RM Johnson, AR Carr, PR McAdam, ... Clinical Cancer Research 26 (3), 657-668, 2020 | 105 | 2020 |
| Faster-X adaptive protein evolution in house mice A Kousathanas, DL Halligan, PD Keightley Genetics 196 (4), 1131-1143, 2014 | 73 | 2014 |
| Dominance and Overdominance of Mildly Deleterious Induced Mutations for Fitness Traits in Caenorhabditis elegans AD Peters, DL Halligan, MC Whitlock, PD Keightley Genetics 165 (2), 589-599, 2003 | 71 | 2003 |
| Evolutionary constraints in conserved nongenic sequences of mammals PD Keightley, GV Kryukov, S Sunyaev, DL Halligan, DJ Gaffney Genome research 15 (10), 1373-1378, 2005 | 67 | 2005 |
| Analysis and implications of mutational variation PD Keightley, DL Halligan Genetica 136, 359-369, 2009 | 56 | 2009 |
Peter KeightleyUniversity of EdinburghVerified email at ed.ac.uk
