Cliona O'Farrelly
Cliona O'Farrelly
Professor of Comparative Immunology
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Liver immunology and its role in inflammation and homeostasis
MW Robinson, C Harmon, C O’Farrelly
Cellular & molecular immunology 13 (3), 267-276, 2016
Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection
L Townsend, AH Dyer, K Jones, J Dunne, A Mooney, F Gaffney, ...
PloS one 15 (11), e0240784, 2020
CD39+ Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
JM Fletcher, R Lonergan, L Costelloe, K Kinsella, B Moran, C O'Farrelly, ...
The Journal of Immunology 183 (11), 7602-7610, 2009
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production
L Lynch, M Nowak, B Varghese, J Clark, AE Hogan, V Toxavidis, SP Balk, ...
Immunity 37 (3), 574-587, 2012
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ...
Nature immunology 19 (12), 1330-1340, 2018
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
Innate and adaptive lymphoid cells in the human liver.
DG Doherty, C O'Farrelly
Immunological reviews 174, 5-20, 2000
Resident human hepatitis lymphocytes are phenotypically different from circulating lymphocytes
S Norris, C Collins, DG Doherty, F Smith, G McEntee, O Traynor, N Nolan, ...
Journal of hepatology 28 (1), 84-90, 1998
The human liver contains multiple populations of NK cells, T cells, and CD3+ CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion …
DG Doherty, S Norris, L Madrigal-Estebas, G McEntee, O Traynor, ...
The Journal of Immunology 163 (4), 2314-2321, 1999
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
Science immunology 6 (62), eabl4348, 2021
Clinical anxiety, cortisol and interleukin-6: Evidence for specificity in emotion–biology relationships
A O’Donovan, BM Hughes, GM Slavich, L Lynch, MT Cronin, C O’Farrelly, ...
Brain, behavior, and immunity 24 (7), 1074-1077, 2010
Persistent poor health after COVID-19 is not associated with respiratory complications or initial disease severity
L Townsend, J Dowds, K O’Brien, G Sheill, AH Dyer, B O’Kelly, JP Hynes, ...
Annals of the American Thoracic Society 18 (6), 997-1003, 2021
Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken
DJ Lynn, R Higgs, S Gaines, J Tierney, T James, AT Lloyd, MA Fares, ...
Immunogenetics 56, 170-177, 2004
Reoxygenation‐specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia‐reperfusion injury
MO Leonard, NE Kieran, K Howell, MJ Burne, R Varadarajan, ...
The FASEB Journal 20 (14), 2624-2626, 2006
Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity
L Lynch, D O'Shea, DC Winter, J Geoghegan, DG Doherty, C O'Farrelly
European journal of immunology 39 (7), 1893-1901, 2009
Are natural killer cells protecting the metabolically healthy obese patient?
LA Lynch, JM O'connell, AK Kwasnik, TJ Cawood, C O'farrelly, DB O'shea
Obesity 17 (3), 601-605, 2009
The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity
J O'Connell, L Lynch, TJ Cawood, A Kwasnik, N Nolan, J Geoghegan, ...
PloS one 5 (4), e9997, 2010
Microanatomy of the liver immune system
E Nemeth, AW Baird, C O’Farrelly
Seminars in immunopathology 31, 333-343, 2009
Smoking and thyroid-associated ophthalmopathy: a novel explanation of the biological link
TJ Cawood, P Moriarty, C O’Farrelly, D O’shea
The Journal of Clinical Endocrinology & Metabolism 92 (1), 59-64, 2007
Induction of a Novel Chicken Toll-Like Receptor following Salmonella enterica Serovar Typhimurium Infection
R Higgs, P Cormican, S Cahalane, B Allan, AT Lloyd, K Meade, T James, ...
Infection and immunity 74 (3), 1692-1698, 2006
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