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JoAnne L. Flynn
JoAnne L. Flynn
Professor of Microbiology and Molecular Genetics, University of Pittsburgh
Verified email at pitt.edu
Title
Cited by
Cited by
Year
An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.
JAL Flynn, J Chan, KJ Triebold, DK Dalton, TA Stewart, BR Bloom
The Journal of experimental medicine 178 (6), 2249-2254, 1993
31211993
Immunology of tuberculosis
JAL Flynn, J Chan
Annual review of immunology 19 (1), 93-129, 2001
28542001
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
23222020
Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice
JAL Flynn, MM Goldstein, J Chan, KJ Triebold, K Pfeffer, CJ Lowenstein, ...
Immunity 2 (6), 561-572, 1995
21721995
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
CE Barry 3rd, HI Boshoff, V Dartois, T Dick, S Ehrt, JA Flynn, ...
Nature Reviews Microbiology 7 (12), 845-855, 2009
16532009
Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.
JAL Flynn, MM Goldstein, KJ Triebold, B Koller, BR Bloom
Proceedings of the National Academy of Sciences 89 (24), 12013-12017, 1992
10761992
IL-17 production is dominated by γδ T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
E Lockhart, AM Green, JAL Flynn
The Journal of Immunology 177 (7), 4662-4669, 2006
10322006
Tuberculosis: latency and reactivation
JAL Flynn, J Chan
Infection and immunity 69 (7), 4195-4201, 2001
7342001
Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
LE Via, PL Lin, SM Ray, J Carrillo, SS Allen, SY Eum, K Taylor, E Klein, ...
Infection and immunity 76 (6), 2333-2340, 2008
7322008
Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology
VP Mohan, CA Scanga, K Yu, HM Scott, KE Tanaka, E Tsang, MC Tsai, ...
Infection and immunity 69 (3), 1847-1855, 2001
7312001
Mice deficient in CD4 T cells have only transiently diminished levels of IFN-γ, yet succumb to tuberculosis
AM Caruso, N Serbina, E Klein, K Triebold, BR Bloom, JAL Flynn
The Journal of Immunology 162 (9), 5407-5416, 1999
7311999
Tuberculosis: what we don’t know can, and does, hurt us
DG Russell, CE Barry 3rd, JAL Flynn
Science 328 (5980), 852-856, 2010
6922010
Understanding latent tuberculosis: a moving target
PL Lin, JAL Flynn
The Journal of Immunology 185 (1), 15-22, 2010
6352010
Activation of human dendritic cells following infection with Mycobacterium tuberculosis.
RA Henderson, SC Watkins, JL Flynn
Journal of immunology (Baltimore, Md.: 1950) 159 (2), 635-643, 1997
5891997
Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection
JAM Tufariello, J Chan, JAL Flynn
The Lancet infectious diseases 3 (9), 578-590, 2003
5832003
Experimental Mycobacterium tuberculosis Infection of Cynomolgus Macaques Closely Resembles the Various Manifestations of Human M. tuberculosis Infection
SV Capuano III, DA Croix, S Pawar, A Zinovik, A Myers, PL Lin, S Bissel, ...
Infection and immunity 71 (10), 5831-5844, 2003
5792003
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis
J Chan, K Tanaka, D Carroll, J Flynn, BR Bloom
Infection and immunity 63 (2), 736-740, 1995
5501995
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
PL Lin, CB Ford, MT Coleman, AJ Myers, R Gawande, T Ioerger, ...
Nature medicine 20 (1), 75-79, 2014
5432014
Macrophages and control of granulomatous inflammation in tuberculosis
JL Flynn, J Chan, PL Lin
Mucosal immunology 4 (3), 271-278, 2011
5122011
Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection
CB Ford, PL Lin, MR Chase, RR Shah, O Iartchouk, J Galagan, ...
Nature genetics 43 (5), 482-486, 2011
5072011
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