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William Bisson
William Bisson
Faculty Member, OHSU Knight Cancer Institute
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Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
L Sun, C Xie, G Wang, Y Wu, Q Wu, X Wang, J Liu, Y Deng, J Xia, B Chen, ...
Nature medicine 24 (12), 1919-1929, 2018
7372018
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
C Jiang, C Xie, Y Lv, J Li, KW Krausz, J Shi, CN Brocker, D Desai, ...
Nature communications 6 (1), 10166, 2015
4972015
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
3372015
Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
TD Hubbard, IA Murray, WH Bisson, TS Lahoti, K Gowda, SG Amin, ...
Scientific reports 5 (1), 12689, 2015
3242015
Colorectal cancer liver metastasis: evolving paradigms and future directions
LR Zarour, S Anand, KG Billingsley, WH Bisson, A Cercek, MF Clarke, ...
Cellular and molecular gastroenterology and hepatology 3 (2), 163-173, 2017
2752017
Estrogen-Like Activity of Perfluoroalkyl Acids In Vivo and Interaction with Human and Rainbow Trout Estrogen Receptors In Vitro
AD Benninghoff, WH Bisson, DC Koch, DJ Ehresman, SK Kolluri, ...
Toxicological sciences 120 (1), 42-58, 2011
2342011
Causes of genome instability: the effect of low dose chemical exposures in modern society
SAS Langie, G Koppen, D Desaulniers, F Al-Mulla, R Al-Temaimi, ...
Carcinogenesis 36 (Suppl_1), S61-S88, 2015
2252015
Environmental immune disruptors, inflammation and cancer risk
PA Thompson, M Khatami, CJ Baglole, J Sun, SA Harris, EY Moon, ...
Carcinogenesis 36 (Suppl_1), S232-S253, 2015
2072015
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
A Sehrawat, L Gao, Y Wang, A Bankhead III, SK McWeeney, CJ King, ...
Proceedings of the National Academy of Sciences 115 (18), E4179-E4188, 2018
1972018
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands
WH Bisson, DC Koch, EF O’Donnell, SM Khalil, NI Kerkvliet, RL Tanguay, ...
Journal of medicinal chemistry 52 (18), 5635-5641, 2009
1652009
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates
P Rajendran, AI Kidane, TW Yu, WM Dashwood, WH Bisson, CV Löhr, ...
Epigenetics 8 (6), 612-623, 2013
1372013
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor
EF O'Donnell, KS Saili, DC Koch, PR Kopparapu, D Farrer, WH Bisson, ...
PloS one 5 (10), e13128, 2010
1352010
TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation
AK Ehrlich, JM Pennington, WH Bisson, SK Kolluri, NI Kerkvliet
Toxicological sciences 161 (2), 310-320, 2018
1342018
The effect of environmental chemicals on the tumor microenvironment
SC Casey, M Vaccari, F Al-Mulla, R Al-Temaimi, A Amedei, ...
Carcinogenesis 36 (Suppl_1), S160-S183, 2015
1282015
Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs
WH Bisson, AV Cheltsov, N Bruey-Sedano, B Lin, J Chen, N Goldberger, ...
Proceedings of the National Academy of Sciences 104 (29), 11927-11932, 2007
1282007
Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism
KJ Smith, IA Murray, R Tanos, J Tellew, AE Boitano, WH Bisson, ...
Journal of Pharmacology and Experimental Therapeutics 338 (1), 318-327, 2011
1192011
Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?
RB Robey, J Weisz, NB Kuemmerle, AC Salzberg, A Berg, DG Brown, ...
Carcinogenesis 36 (Suppl_1), S203-S231, 2015
1182015
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish
BC Goodale, JK La Du, WH Bisson, DB Janszen, KM Waters, RL Tanguay
PloS one 7 (1), e29346, 2012
1052012
Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors
M Ceccon, L Mologni, W Bisson, L Scapozza, C Gambacorti-Passerini
Molecular Cancer Research 11 (2), 122-132, 2013
1022013
α-Keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells
H Nian, WH Bisson, WM Dashwood, JT Pinto, RH Dashwood
Carcinogenesis 30 (8), 1416-1423, 2009
1012009
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