The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity L de Lecea, TS Kilduff, C Peyron, XB Gao, PE Foye, PE Danielson, ... Proceedings of the National Academy of Sciences 95 (1), 322-327, 1998 | 4493 | 1998 |
Neurons containing hypocretin (orexin) project to multiple neuronal systems C Peyron, DK Tighe, AN Van Den Pol, L De Lecea, HC Heller, JG Sutcliffe, ... Journal of Neuroscience 18 (23), 9996-10015, 1998 | 4019 | 1998 |
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system TL Horvath, C Peyron, S Diano, A Ivanov, G Aston‐Jones, TS Kilduff, ... Journal of Comparative Neurology 415 (2), 145-159, 1999 | 713 | 1999 |
Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin AN Van Den Pol, XB Gao, K Obrietan, TS Kilduff, AB Belousov Journal of Neuroscience 18 (19), 7962-7971, 1998 | 639 | 1998 |
The hypocretin/orexin ligand–receptor system: implications for sleep and sleep disorders TS Kilduff, C Peyron Trends in neurosciences 23 (8), 359-365, 2000 | 540 | 2000 |
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response R Winsky-Sommerer, A Yamanaka, S Diano, E Borok, AJ Roberts, ... Journal of Neuroscience 24 (50), 11439-11448, 2004 | 503 | 2004 |
A role for cryptochromesin sleep regulation JP Wisor, BF O'Hara, A Terao, CP Selby, TS Kilduff, A Sancar, DM Edgar, ... BMC neuroscience 3, 1-14, 2002 | 337 | 2002 |
Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat D Gerashchenko, MD Kohls, MA Greco, NS Waleh, R Salin-Pascual, ... Journal of Neuroscience 21 (18), 7273-7283, 2001 | 318 | 2001 |
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic-and antidepressant-like activity, improve cognition and control body weight FG Revel, JL Moreau, B Pouzet, R Mory, A Bradaia, D Buchy, V Metzler, ... Molecular psychiatry 18 (5), 543-556, 2013 | 290 | 2013 |
Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice T Tsunematsu, TS Kilduff, ES Boyden, S Takahashi, M Tominaga, ... Journal of Neuroscience 31 (29), 10529-10539, 2011 | 274 | 2011 |
The neurobiology of sleep and wakefulness MD Schwartz, TS Kilduff Psychiatric Clinics 38 (4), 615-644, 2015 | 241 | 2015 |
Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor Y Muraki, A Yamanaka, N Tsujino, TS Kilduff, K Goto, T Sakurai Journal of Neuroscience 24 (32), 7159-7166, 2004 | 241 | 2004 |
Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation T Tsunematsu, T Ueno, S Tabuchi, A Inutsuka, KF Tanaka, H Hasuwa, ... Journal of Neuroscience 34 (20), 6896-6909, 2014 | 235 | 2014 |
Identification of a population of sleep-active cerebral cortex neurons D Gerashchenko, JP Wisor, D Burns, RK Reh, PJ Shiromani, T Sakurai, ... Proceedings of the National Academy of Sciences 105 (29), 10227-10232, 2008 | 219 | 2008 |
Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function S Tabuchi, T Tsunematsu, SW Black, M Tominaga, M Maruyama, ... Journal of Neuroscience 34 (19), 6495-6509, 2014 | 218 | 2014 |
REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories S Izawa, S Chowdhury, T Miyazaki, Y Mukai, D Ono, R Inoue, Y Ohmura, ... Science 365 (6459), 1308-1313, 2019 | 186 | 2019 |
Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics FG Revel, JL Moreau, RR Gainetdinov, A Ferragud, ... Biological psychiatry 72 (11), 934-942, 2012 | 181 | 2012 |
Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep A Terao, TL Steininger, K Hyder, A Apte-Deshpande, J Ding, ... Neuroscience 116 (1), 187-200, 2003 | 172 | 2003 |
Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor N Tsujino, A Yamanaka, K Ichiki, Y Muraki, TS Kilduff, K Yagami, ... Journal of Neuroscience 25 (32), 7459-7469, 2005 | 165 | 2005 |
Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains JP Wisor, RK Pasumarthi, D Gerashchenko, CL Thompson, S Pathak, ... Journal of Neuroscience 28 (28), 7193-7201, 2008 | 160 | 2008 |