| Mini-G proteins: Novel tools for studying GPCRs in their active conformation R Nehme, B Carpenter, A Singhal, A Strege, PC Edwards, CF White, H Du, ... PloS one 12 (4), e0175642, 2017 | 231 | 2017 |
| Structure and dynamics of a constitutively active neurotensin receptor BE Krumm, S Lee, S Bhattacharya, I Botos, CF White, H Du, N Vaidehi, ... Scientific reports 6 (1), 38564, 2016 | 67 | 2016 |
| Detection and characterization of the in vitro e3 ligase activity of the human MID1 protein X Han, H Du, MA Massiah Journal of molecular biology 407 (4), 505-520, 2011 | 51 | 2011 |
| Obtaining soluble folded proteins from inclusion bodies using sarkosyl, triton X‐100, and CHAPS: application to LB and M9 minimal media MA Massiah, KM Wright, H Du Current protocols in protein science 84 (1), 6.13. 1-6.13. 24, 2016 | 47 | 2016 |
| The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A H Du, Y Huang, M Zaghlula, E Walters, TC Cox, MA Massiah Journal of Biological Chemistry 288 (29), 21341-21350, 2013 | 46 | 2013 |
| Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability L Wang, MC Casey, SKV Vernekar, RL Sahani, KA Kirby, H Du, H Zhang, ... Acta Pharmaceutica Sinica B 11 (3), 810-822, 2021 | 25 | 2021 |
| The structure and behavior of the NA-CATH antimicrobial peptide with liposomes H Du, RL Samuel, MA Massiah, SD Gillmor Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2394-2405, 2015 | 25 | 2015 |
| Toward structurally novel and metabolically stable HIV-1 capsid-targeting small molecules SKV Vernekar, RL Sahani, MC Casey, J Kankanala, L Wang, KA Kirby, ... Viruses 12 (4), 452, 2020 | 24 | 2020 |
| MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac H Du, K Wu, A Didoronkute, MVA Levy, N Todi, A Shchelokova, ... PLoS One 9 (9), e107428, 2014 | 24 | 2014 |
| Chemical profiling of HIV-1 capsid-targeting antiviral PF74 L Wang, MC Casey, SKV Vernekar, HT Do, RL Sahani, KA Kirby, H Du, ... European journal of medicinal chemistry 200, 112427, 2020 | 21 | 2020 |
| Novel HIV-1 capsid-targeting small molecules of the PF74 binding site L Wang, MC Casey, SKV Vernekar, RL Sahani, J Kankanala, KA Kirby, ... European journal of medicinal chemistry 204, 112626, 2020 | 19 | 2020 |
| Discovery of new small molecule hits as Hepatitis B virus capsid assembly modulators: structure and pharmacophore-based approaches S Senaweera, H Du, H Zhang, KA Kirby, PR Tedbury, J Xie, ... Viruses 13 (5), 770, 2021 | 18 | 2021 |
| Solution structure of the microtubule‐targeting COS domain of MID1 KM Wright, H Du, M Dagnachew, MA Massiah The FEBS Journal 283 (16), 3089-3102, 2016 | 16 | 2016 |
| Design, synthesis and characterization of HIV-1 CA-targeting small molecules: conformational restriction of PF74 RL Sahani, R Diana-Rivero, SKV Vernekar, L Wang, H Du, H Zhang, ... Viruses 13 (3), 479, 2021 | 13 | 2021 |
| Insulin analogs with B24 or B25 phenylalanine replaced by biphenylalanine H Du, J Shi, D Cui, Y Zhang Acta biochimica et biophysica Sinica 40 (2), 133-139, 2008 | 13 | 2008 |
| XLOS-observed mutations of MID1 Bbox1 domain cause domain unfolding KM Wright, K Wu, O Babatunde, H Du, MA Massiah PLoS One 9 (9), e107537, 2014 | 8 | 2014 |
| Structural and functional observations of the P151L MID 1 mutation reveal alpha4 plays a significant role in X‐linked Opitz Syndrome KM Wright, H Du, MA Massiah The FEBS Journal 284 (14), 2183-2193, 2017 | 7 | 2017 |
| NMR studies of the C-terminus of alpha4 reveal possible mechanism of its interaction with MID1 and protein phosphatase 2A H Du, MA Massiah PloS one 6 (12), e28877, 2011 | 7 | 2011 |
| B22 Glu des‐B30 insulin: A novel monomeric insulin HJ DU, JH SHI, DF CUI, YS ZHANG Acta Biochimica et Biophysica Sinica 38 (8), 537-542, 2006 | 6 | 2006 |
| Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host … S Lan, PR Tedbury, YT Ong, R Shah, RL Slack, ME Cilento, H Zhang, ... bioRxiv, 2021.12. 29.474471, 2021 | 5 | 2021 |
