Stephen Jackson
Stephen Jackson
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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H Farmer, N McCabe, CJ Lord, ANJ Tutt, DA Johnson, TB Richardson, ...
Nature 434 (7035), 917-921, 2005
The DNA-damage response in human biology and disease
SP Jackson, J Bartek
Nature 461 (7267), 1071-1078, 2009
DNA double-strand breaks: signaling, repair and the cancer connection
KK Khanna, SP Jackson
Nature genetics 27 (3), 247-254, 2001
A DNA damage checkpoint response in telomere-initiated senescence
FA di Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, ...
Nature 426 (6963), 194-198, 2003
Sensing and repairing DNA double-strand breaks
SP Jackson
Carcinogenesis 23 (5), 687-696, 2002
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
J Falck, J Coates, SP Jackson
Nature 434 (7033), 605-611, 2005
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
TM Gottlieb, SP Jackson
Cell 72 (1), 131-142, 1993
Human CtIP promotes DNA end resection
AA Sartori, C Lukas, J Coates, M Mistrik, S Fu, J Bartek, R Baer, J Lukas, ...
Nature 450 (7169), 509-514, 2007
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
I Hickson, Y Zhao, CJ Richardson, SJ Green, NMB Martin, AI Orr, ...
Cancer research 64 (24), 9152-9159, 2004
ATM-and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri, J Falck, C Lukas, J Bartek, GCM Smith, J Lukas, SP Jackson
Nature cell biology 8 (1), 37-45, 2006
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
M Stucki, JA Clapperton, D Mohammad, MB Yaffe, SJ Smerdon, ...
Cell 123 (7), 1213-1226, 2005
The DNA-dependent protein kinase
GCM Smith, SP Jackson
Genes & development 13 (8), 916-934, 1999
The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling
D D'amours, SP Jackson
Nature reviews Molecular cell biology 3 (5), 317-327, 2002
Regulation of p53 in response to DNA damage
ND Lakin, SP Jackson
Oncogene 18 (53), 7644-7655, 1999
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
SE Polo, SP Jackson
Genes & development 25 (5), 409-433, 2011
O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation
SP Jackson, R Tjian
Cell 55 (1), 125-133, 1988
Defective DNA-dependent protein kinase activity is linked to V (D) J recombination and DNA repair defects associated with the murine scid mutation
T Blunt, NJ Finnie, GE Taccioli, GCM Smith, J Demengeot, TM Gottlieb, ...
Cell 80 (5), 813-823, 1995
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ...
Science 318 (5856), 1637-1640, 2007
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to γ-H2AX foci
E Riballo, M Kühne, N Rief, A Doherty, GCM Smith, MJ Recio, C Reis, ...
Molecular cell 16 (5), 715-724, 2004
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
P Ahnesorg, P Smith, SP Jackson
Cell 124 (2), 301-313, 2006
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