The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence I Bruns, A Czibere, JC Fischer, F Roels, RP Cadeddu, S Buest, ... Leukemia 23 (5), 892-899, 2009 | 118 | 2009 |
Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus ileboensis with potent activities against Plasmodium falciparum … J Li, R Seupel, D Feineis, V Mudogo, M Kaiser, R Brun, D Brünnert, ... Journal of natural products 80 (2), 443-458, 2017 | 81 | 2017 |
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent … R Singh, RP Cadeddu, J Fröbel, CM Wilk, I Bruns, LF Zerbini, T Prenzel, ... Apoptosis 16, 889-901, 2011 | 58 | 2011 |
Polymorphism of the IL-8 gene and the risk of ovarian cancer D Koensgen, D Bruennert, S Ungureanu, D Sofroni, EI Braicu, J Sehouli, ... Cytokine 71 (2), 334-338, 2015 | 45 | 2015 |
Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways P Goyal, D Brünnert, J Ehrhardt, M Bredow, S Piccenini, M Zygmunt MHR: Basic science of reproductive medicine 19 (8), 528-538, 2013 | 44 | 2013 |
Identification of gefitinib off-targets using a structure-based systems biology approach; their validation with reverse docking and retrospective data mining N Verma, AK Rai, V Kaushik, D Brünnert, KR Chahar, J Pandey, P Goyal Scientific Reports 6 (1), 1-12, 2016 | 37 | 2016 |
Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation P Goyal, D Pandey, D Brünnert, E Hammer, M Zygmunt, W Siess PLoS One 8 (8), e71769, 2013 | 36 | 2013 |
Early in vivo changes of the transcriptome in Philadelphia chromosome-positive CD34+ cells from patients with chronic myelogenous leukaemia following imatinib therapy D Bruennert, A Czibere, I Bruns, R Kronenwett, N Gattermann, R Haas, ... Leukemia 23 (5), 983-985, 2009 | 32 | 2009 |
The heat shock protein 70 inhibitor VER155008 suppresses the expression of HSP27, HOP and HSP90β and the androgen receptor, induces apoptosis, and attenuates prostate cancer … D Brünnert, C Langer, L Zimmermann, RC Bargou, M Burchardt, ... Journal of Cellular Biochemistry 121 (1), 407-417, 2020 | 30 | 2020 |
Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells D Brünnert, M Sztachelska, F Bornkessel, N Treder, S Wolczynski, ... MHR: Basic science of reproductive medicine 20 (10), 1016-1025, 2014 | 29 | 2014 |
High prevalence of intestinal pathogens in indigenous in Colombia S Kann, D Bruennert, J Hansen, GAC Mendoza, JJC Gonzalez, ... Journal of Clinical Medicine 9 (9), 2786, 2020 | 26 | 2020 |
Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma D Brünnert, M Kraus, T Stuehmer, S Kirner, R Heiden, P Goyal, ... Biochimica et biophysica acta (BBA)-molecular basis of disease 1865 (6 …, 2019 | 24 | 2019 |
Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells D Brünnert, S Piccenini, J Ehrhardt, M Zygmunt, P Goyal Placenta 36 (10), 1115-1121, 2015 | 19 | 2015 |
Ugi reaction-derived α-acyl aminocarboxamides bind to phosphatidylinositol 3-kinase-related kinases, inhibit HSF1-dependent heat shock response, and induce apoptosis in … M Bach, A Lehmann, D Brünnert, JT Vanselow, A Hartung, RC Bargou, ... Journal of Medicinal Chemistry 60 (10), 4147-4160, 2017 | 18 | 2017 |
RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS M Seibold, T Stühmer, N Kremer, A Mottok, CJ Scholz, A Schlosser, ... Haematologica 105 (9), 2316, 2020 | 17 | 2020 |
Pan-Raf co-operates with PI3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated RAS E Müller, S Bauer, T Stühmer, A Mottok, CJ Scholz, T Steinbrunn, ... Leukemia 31 (4), 922-933, 2017 | 17 | 2017 |
T and NK cells of B cell NHL patients exert cytotoxicity against lymphoma cells following binding of bispecific tetravalent antibody CD19× CD3 or CD19× CD16 LM Pörtner, K Schönberg, M Hejazi, D Brünnert, F Neumann, L Galonska, ... Cancer Immunology, Immunotherapy 61, 1869-1875, 2012 | 12 | 2012 |
Thrombin stimulates gene expression and secretion of IL-11 via protease-activated receptor-1 and regulates extravillous trophoblast cell migration D Brünnert, I Shekhawat, KR Chahar, J Ehrhardt, J Pandey, JK Yadav, ... Journal of reproductive immunology 132, 35-41, 2019 | 11 | 2019 |
Expression, intracellular localization, and prognostic value of plasminogen activator inhibitor 1 and PAI-1 RNA-binding protein 1 in primary and recurrent ovarian cancer: a … D Koensgen, MB Stope, I Tuerbachova, D Bruennert, T Kohlmann, ... Gynecologic and Obstetric Investigation 83 (5), 508-514, 2018 | 10 | 2018 |
Thrombin impairs the angiogenic activity of extravillous trophoblast cells via monocyte chemotactic protein-1 (MCP-1): A possible link with preeclampsia D Brünnert, V Kumar, V Kaushik, J Ehrhardt, KR Chahar, PK Sharma, ... Reproductive Biology 21 (3), 100516, 2021 | 9 | 2021 |