Bruce S. Edwards
Bruce S. Edwards
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Virtual and biomolecular screening converge on a selective agonist for GPR30
CG Bologa, CM Revankar, SM Young, BS Edwards, JB Arterburn, ...
Nature chemical biology 2 (4), 207, 2006
Flow cytometry for high-throughput, high-content screening
BS Edwards, T Oprea, ER Prossnitz, LA Sklar
Current opinion in chemical biology 8 (4), 392-398, 2004
Drug repurposing from an academic perspective
TI Oprea, JE Bauman, CG Bologa, T Buranda, A Chigaev, BS Edwards, ...
Drug Discovery Today: Therapeutic Strategies 8 (3-4), 61-69, 2011
Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance
EK Sully, N Malachowa, BO Elmore, SM Alexander, JK Femling, BM Gray, ...
PLoS pathogens 10 (6), e1004174, 2014
Real time analysis of the affinity regulation of α4-integrin the physiologically activated receptor is intermediate in affinity between resting and Mn2+ or antibody activation
A Chigaev, AM Blenc, JV Braaten, N Kumaraswamy, CL Kepley, ...
Journal of Biological Chemistry 276 (52), 48670-48678, 2001
High throughput flow cytometry
FW Kuckuck, BS Edwards, LA Sklar
Cytometry: The Journal of the International Society for Analytical Cytology …, 2001
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes
TA Bennett, BS Edwards, LA Sklar, S Rogelj
The Journal of Immunology 164 (8), 4120-4129, 2000
Flow cytometry for high throughput screening
LA Sklar, BS Edwards, FW Kuckuck
US Patent 6,890,487, 2005
Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists
BS Edwards, C Bologa, SM Young, KV Balakin, ER Prossnitz, ...
Molecular pharmacology 68 (5), 1301-1310, 2005
Low doses of interferon alpha result in more effective clinical natural killer cell activation.
BS Edwards, JA Merritt, RC Fuhlbrigge, EC Borden
The Journal of clinical investigation 75 (6), 1908-1913, 1985
Advancing biological understanding and therapeutics discovery with small-molecule probes
SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ...
Cell 161 (6), 1252-1265, 2015
Flow cytometric analysis of ligand-receptor interactions and molecular assemblies
LA Sklar, BS Edwards, SW Graves, JP Nolan, ER Prossnitz
Annual review of biophysics and biomolecular structure 31 (1), 97-119, 2002
Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening
LA Sklar, MB Carter, BS Edwards
Current opinion in pharmacology 7 (5), 527-534, 2007
α4β1 integrin affinity changes govern cell adhesion
A Chigaev, G Zwartz, SW Graves, DC Dwyer, H Tsuji, TD Foutz, ...
Journal of Biological Chemistry 278 (40), 38174-38182, 2003
Lymphocyte subset analysis by flow cytometry Comparison of three different staining techniques and effects of blood storage
LM Ashmore, GM Shopp, BS Edwards
Journal of immunological methods 118 (2), 209-215, 1989
Sample handling for kinetics and molecular assembly in flow cytometry
LA Sklar, LC Seamer, FW Kuckuck III, RG Posner, ER Prossnitz, ...
Advances in Optical Biophysics 3256, 144-153, 1998
The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures
GS Davidson, RM Joe, S Roy, O Meirelles, CP Allen, MR Wilson, ...
Molecular biology of the cell 22 (7), 988-998, 2011
High-throughput screening with HyperCyt® flow cytometry to detect small molecule formylpeptide receptor ligands
SM Young, C Bologa, ER Prossnitz, TI Oprea, LA Sklar, BS Edwards
Journal of biomolecular screening 10 (4), 374-382, 2005
High‐throughput flow cytometry: Validation in microvolume bioassays
S Ramirez, CT Aiken, B Andrzejewski, LA Sklar, BS Edwards
Cytometry Part A: the journal of the International Society for Analytical …, 2003
Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay
Z Surviladze, A Waller, Y Wu, E Romero, BS Edwards, A Wandinger-Ness, ...
Journal of biomolecular screening 15 (1), 10-20, 2010
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