| Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly (ethylene imine)-graft-poly (ethylene glycol) block copolymer/SiRNA … S Mao, M Neu, O Germershaus, O Merkel, J Sitterberg, U Bakowsky, ... Bioconjugate chemistry 17 (5), 1209-1218, 2006 | 352 | 2006 |
| Stability of siRNA polyplexes from poly (ethylenimine) and poly (ethylenimine)-g-poly (ethylene glycol) under in vivo conditions: effects on pharmacokinetics and … OM Merkel, D Librizzi, A Pfestroff, T Schurrat, K Buyens, N Sanders, ... Journal of Controlled Release 138 (2), 148-159, 2009 | 205 | 2009 |
| Nonviral siRNA delivery to the lung: Investigation of PEG− PEI polyplexes and their in vivo performance OM Merkel, A Beyerle, D Librizzi, A Pfestroff, TM Behr, B Sproat, PJ Barth, ... Molecular pharmaceutics 6 (4), 1246-1260, 2009 | 176 | 2009 |
| In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (–PEG)/siRNA complexes A Malek, O Merkel, L Fink, F Czubayko, T Kissel, A Aigner Toxicology and applied pharmacology 236 (1), 97-108, 2009 | 176 | 2009 |
| Controlled pulmonary drug and gene delivery using polymeric nano-carriers M Beck-Broichsitter, OM Merkel, T Kissel Journal of controlled release 161 (2), 214-224, 2012 | 171 | 2012 |
| Applications of polymer micelles for imaging and drug delivery S Movassaghian, OM Merkel, VP Torchilin Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7 (5 …, 2015 | 143 | 2015 |
| Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy J Nguyen, TWJ Steele, O Merkel, R Reul, T Kissel Journal of Controlled Release 132 (3), 243-251, 2008 | 132 | 2008 |
| In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly (ethylene glycol) block copolymers OM Merkel, R Urbanics, P Bedőcs, Z Rozsnyay, L Rosivall, M Toth, ... Biomaterials 32 (21), 4936-4942, 2011 | 120 | 2011 |
| Nonviral pulmonary delivery of siRNA OM Merkel, T Kissel Accounts of chemical research 45 (7), 961-970, 2012 | 100 | 2012 |
| Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity OM Merkel, MA Mintzer, D Librizzi, O Samsonova, T Dicke, B Sproat, ... Molecular pharmaceutics 7 (4), 969-983, 2010 | 99 | 2010 |
| In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure OM Merkel, D Librizzi, A Pfestroff, T Schurrat, M Béhé, T Kissel Bioconjugate chemistry 20 (1), 174-182, 2009 | 97 | 2009 |
| Polymer-related off-target effects in non-viral siRNA delivery OM Merkel, A Beyerle, BM Beckmann, M Zheng, RK Hartmann, T Stöger, ... Biomaterials 32 (9), 2388-2398, 2011 | 94 | 2011 |
| siRNA delivery to the lung: what's new? OM Merkel, I Rubinstein, T Kissel Advanced drug delivery reviews 75, 112-128, 2014 | 91 | 2014 |
| Comparative in vivo study of poly (ethylene imine)/siRNA complexes for pulmonary delivery in mice A Beyerle, A Braun, O Merkel, F Koch, T Kissel, T Stoeger Journal of controlled release 151 (1), 51-56, 2011 | 86 | 2011 |
| Computational insights into the interactions between DNA and siRNA with “rigid” and “flexible” triazine dendrimers GM Pavan, MA Mintzer, EE Simanek, OM Merkel, T Kissel, A Danani Biomacromolecules 11 (3), 721-730, 2010 | 86 | 2010 |
| Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity OM Merkel, MA Mintzer, J Sitterberg, U Bakowsky, EE Simanek, T Kissel Bioconjugate chemistry 20 (9), 1799-1806, 2009 | 84 | 2009 |
| Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly (ethylene glycol) copolymers M Zheng, D Librizzi, A Kılıç, Y Liu, H Renz, OM Merkel, T Kissel Biomaterials 33 (27), 6551-6558, 2012 | 80 | 2012 |
| PEGylation affects cytotoxicity and cell-compatibility of poly (ethylene imine) for lung application: structure–function relationships A Beyerle, O Merkel, T Stoeger, T Kissel Toxicology and applied pharmacology 242 (2), 146-154, 2010 | 79 | 2010 |
| Targeting the blind spot of polycationic nanocarrier-based siRNA delivery M Zheng, GM Pavan, M Neeb, AK Schaper, A Danani, G Klebe, ... ACS nano 6 (11), 9447-9454, 2012 | 78 | 2012 |
| Amphiphilic Biodegradable PEG-PCL-PEI Triblock Copolymers for FRET-Capable in Vitro and in Vivo Delivery of siRNA and Quantum Dots T Endres, M Zheng, A Kılıç, A Turowska, M Beck-Broichsitter, H Renz, ... Molecular pharmaceutics 11 (4), 1273-1281, 2014 | 77 | 2014 |
Tobias StoegerHelmholtz Zentrum MünchenEmail verificata su helmholtz-muenchen.de
