| Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging C Schiller, CP Fröhlich, T Giessmann, W Siegmund, H Mönnikes, ... Alimentary pharmacology & therapeutics 22 (10), 971-979, 2005 | 678 | 2005 |
| Deposition of Alzheimer's β-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans S Vogelgesang, I Cascorbi, E Schroeder, J Pahnke, HK Kroemer, ... Pharmacogenetics and Genomics 12 (7), 535-541, 2002 | 436 | 2002 |
| Induction of P‐glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction K Westphal, A Weinbrenner, M Zschiesche, G Franke, M Knoke, R Oertel, ... Clinical Pharmacology & Therapeutics 68 (4), 345-355, 2000 | 357 | 2000 |
| The effect of rifampin treatment on intestinal expression of human MRP transporters MF Fromm, HM Kauffmann, P Fritz, O Burk, HK Kroemer, RW Warzok, ... The American journal of pathology 157 (5), 1575-1580, 2000 | 352 | 2000 |
| Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters M Leonhardt, M Keiser, S Oswald, J Kühn, J Jia, M Grube, HK Kroemer, ... Drug Metabolism and Disposition 38 (7), 1024-1028, 2010 | 274 | 2010 |
| Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine M Drozdzik, C Gröer, J Penski, J Lapczuk, M Ostrowski, Y Lai, B Prasad, ... Molecular pharmaceutics 11 (10), 3547-3555, 2014 | 273 | 2014 |
| The effects of the human MDR1 genotype on the expression of duodenal P‐glycoprotein and disposition of the probe drug talinolol W Siegmund, K Ludwig, T Giessmann, P Dazert, E Schroeder, B Sperker, ... Clinical pharmacology & therapeutics 72 (5), 572-583, 2002 | 268 | 2002 |
| Organic anion transporting polypeptide 2B1 is a high‐affinity transporter for atorvastatin and is expressed in the human heart M Grube, K Köck, S Oswald, K Draber, K Meissner, L Eckel, M Böhm, ... Clinical Pharmacology & Therapeutics 80 (6), 607-620, 2006 | 255 | 2006 |
| Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P‐glycoprotein K Westphal, A Weinbrenner, T Giessmann, M Stuhr, G Franke, ... Clinical Pharmacology & Therapeutics 68 (1), 6-12, 2000 | 227 | 2000 |
| Carbamazepine regulates intestinal P‐glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans T Giessmann, K May, C Modess, D Wegner, U Hecker, M Zschiesche, ... Clinical Pharmacology & Therapeutics 76 (3), 192-200, 2004 | 220 | 2004 |
| Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses G Garbacz, RS Wedemeyer, S Nagel, T Giessmann, H Mönnikes, ... European Journal of Pharmaceutics and Biopharmaceutics 70 (2), 421-428, 2008 | 208 | 2008 |
| Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14: 1) is not superior to thyroxine alone to improve well‐being and cognitive performance … W Siegmund, K Spieker, AI Weike, T Giessmann, C Modess, T Dabers, ... Clinical endocrinology 60 (6), 750-757, 2004 | 203 | 2004 |
| The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease S Vogelgesang, RW Warzok, I Cascorbi, C Kunert-Keil, E Schroeder, ... Current Alzheimer Research 1 (2), 121-125, 2004 | 201 | 2004 |
| Intragastric pH and pressure profiles after intake of the high-caloric, high-fat meal as used for food effect studies M Koziolek, F Schneider, M Grimm, C Modeβ, A Seekamp, T Roustom, ... Journal of controlled release 220, 71-78, 2015 | 163 | 2015 |
| Navigating the human gastrointestinal tract for oral drug delivery: Uncharted waters and new frontiers M Koziolek, M Grimm, F Schneider, P Jedamzik, M Sager, JP Kühn, ... Advanced Drug Delivery Reviews 101, 75-88, 2016 | 162 | 2016 |
| Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid–enhanced MR imaging A Nassif, J Jia, M Keiser, S Oswald, C Modess, S Nagel, W Weitschies, ... Radiology 264 (3), 741-750, 2012 | 161 | 2012 |
| Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival Y Guo, K Köck, CA Ritter, ZS Chen, M Grube, G Jedlitschky, T Illmer, ... Clinical Cancer Research 15 (5), 1762-1769, 2009 | 156 | 2009 |
| Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1 K Mandery, K Bujok, I Schmidt, M Keiser, W Siegmund, B Balk, J König, ... Biochemical pharmacology 80 (11), 1746-1753, 2010 | 154 | 2010 |
| CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects T Giessmann, C Modess, U Hecker, M Zschiesche, P Dazert, ... Clinical Pharmacology & Therapeutics 75 (3), 213-222, 2004 | 154 | 2004 |
| LC–MS/MS-based quantification of clinically relevant intestinal uptake and efflux transporter proteins C Gröer, S Brück, Y Lai, A Paulick, A Busemann, CD Heidecke, ... Journal of pharmaceutical and biomedical analysis 85, 253-261, 2013 | 153 | 2013 |
