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Edward L. Y. Chen
Edward L. Y. Chen
Postdoctoral Fellow, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Verified email at mail.utoronto.ca
Title
Cited by
Cited by
Year
RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors
ELY Chen, PK Thompson, JC Zúñiga-Pflücker
Nature Immunology 20 (11), 1456-1468, 2019
762019
Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much?
P Zarin, ELY Chen, TSH In, MK Anderson, JC Zúñiga-Pflücker
Cellular Immunology 296 (1), 70-75, 2015
712015
Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells
PM Benveniste, S Roy, M Nakatsugawa, ELY Chen, L Nguyen, DG Millar, ...
Science Immunology 3 (30), eaav4036, 2018
542018
HEB is required for the specification of fetal IL-17-producing γδ T cells
TSH In, A Trotman-Grant, S Fahl, ELY Chen, P Zarin, AJ Moore, DL Wiest, ...
Nature Communications 8 (1), 2004, 2017
512017
NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development
J Li, J Gordon, ELY Chen, S Xiao, L Wu, JC Zúñiga-Pflücker, NR Manley
Development 147 (12), dev178988, 2020
302020
Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation
P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, ...
Immunology and Cell Biology 96 (9), 994-1007, 2018
222018
Peroxisome Proliferator-Activated Receptor–δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4+ T Cells
FL Zhao, JJ Ahn, ELY Chen, TJ Yi, NH Stickle, D Spaner, ...
The Journal of Immunology 201 (9), 2664-2682, 2018
192018
Generation and function of progenitor T cells from StemRegenin-1–expanded CD34+ human hematopoietic progenitor cells
J Singh, ELY Chen, Y Xing, HE Stefanski, BR Blazar, JC Zúñiga-Pflücker
Blood Advances 3 (20), 2934-2948, 2019
172019
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer
D Dervovic, AA Malik, ELY Chen, M Narimatsu, N Adler, S Afiuni-Zadeh, ...
Nature Communications 14 (1), 3150, 2023
112023
Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo
ELY Chen, CR Lee, PK Thompson, DL Wiest, MK Anderson, ...
Cell Reports 35 (10), 109227, 2021
92021
T-Cell Development: From T-Lineage Specification to Intrathymic Maturation
K Yoganathan, ELY Chen, J Singh, JC Zúñiga-Pflücker
Thymus Transcriptome and Cell Biology, 67-115, 2019
62019
Cutting Edge: TCR-β Selection Is Required at the CD4+CD8+ Stage of Human T Cell Development
ELY Chen, PM Brauer, EC Martinez, X Huang, N Yu, MK Anderson, Y Li, ...
The Journal of Immunology 206 (10), 2271-2276, 2021
52021
Realization of the T Lineage Program Involves GATA-3 Induction of Bcl11b and Repression of Cdkn2b Expression
PK Thompson, ELY Chen, RF de Pooter, C Frelin, WK Vogel, CR Lee, ...
The Journal of Immunology 209 (1), 77-92, 2022
12022
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