Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment R Kojima, D Bojar, G Rizzi, GCE Hamri, MD El-Baba, P Saxena, ... Nature communications 9 (1), 1305, 2018 | 542 | 2018 |
Programmable single-cell mammalian biocomputers S Ausländer, D Ausländer, M Müller, M Wieland, M Fussenegger Nature 487 (7405), 123-127, 2012 | 433 | 2012 |
Synthetic biology—the synthesis of biology S Ausländer, D Ausländer, M Fussenegger Angewandte Chemie International Edition 56 (23), 6396-6419, 2017 | 188 | 2017 |
A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression S Ausländer, P Ketzer, JS Hartig Molecular BioSystems 6 (5), 807-814, 2010 | 176 | 2010 |
From gene switches to mammalian designer cells: present and future prospects S Ausländer, M Fussenegger Trends in biotechnology 31 (3), 155-168, 2013 | 150 | 2013 |
A synthetic multifunctional mammalian pH sensor and CO2 transgene-control device D Ausländer, S Ausländer, G Charpin-El Hamri, F Sedlmayer, M Müller, ... Molecular cell 55 (3), 397-408, 2014 | 119 | 2014 |
A general design strategy for protein-responsive riboswitches in mammalian cells S Ausländer, P Stücheli, C Rehm, D Ausländer, JS Hartig, M Fussenegger Nature methods 11 (11), 1154-1160, 2014 | 108 | 2014 |
Methylated DNA causes a physical block to replication forks independently of damage signalling, O6-methylguanine or DNA single-strand breaks and results in DNA damage P Groth, S Ausländer, MM Majumder, N Schultz, F Johansson, ... Journal of molecular biology 402 (1), 70-82, 2010 | 89 | 2010 |
Programmable full-adder computations in communicating three-dimensional cell cultures D Ausländer, S Ausländer, X Pierrat, L Hellmann, L Rachid, ... Nature methods 15 (1), 57-60, 2018 | 75 | 2018 |
A designer cell-based histamine-specific human allergy profiler D Ausländer, B Eggerschwiler, C Kemmer, B Geering, S Ausländer, ... Nature communications 5 (1), 4408, 2014 | 74 | 2014 |
A novel reporter system for bacterial and mammalian cells based on the non-ribosomal peptide indigoidine M Müller, S Ausländer, D Ausländer, C Kemmer, M Fussenegger Metabolic engineering 14 (4), 325-335, 2012 | 64 | 2012 |
Smart medication through combination of synthetic biology and cell microencapsulation S Ausländer, M Wieland, M Fussenegger Metabolic engineering 14 (3), 252-260, 2012 | 60 | 2012 |
Rational design of a small molecule-responsive intramer controlling transgene expression in mammalian cells D Ausländer, M Wieland, S Ausländer, M Tigges, M Fussenegger Nucleic acids research 39 (22), e155-e155, 2011 | 60 | 2011 |
Designed cell consortia as fragrance-programmable analog-to-digital converters M Müller, S Ausländer, A Spinnler, D Ausländer, J Sikorski, M Folcher, ... Nature chemical biology 13 (3), 309-316, 2017 | 57 | 2017 |
Engineering gene circuits for mammalian cell–based applications S Ausländer, M Fussenegger Cold Spring Harbor perspectives in biology 8 (7), a023895, 2016 | 56 | 2016 |
Synthetic RNA-based switches for mammalian gene expression control S Ausländer, M Fussenegger Current Opinion in Biotechnology 48, 54-60, 2017 | 44 | 2017 |
Post-transcriptional Boolean computation by combining aptazymes controlling mRNA translation initiation and tRNA activation B Klauser, A Saragliadis, S Ausländer, M Wieland, MR Berthold, JS Hartig Molecular BioSystems 8 (9), 2242-2248, 2012 | 39 | 2012 |
Engineering a ribozyme cleavage-induced split fluorescent aptamer complementation assay S Ausländer, D Fuchs, S Hürlemann, D Ausländer, M Fussenegger Nucleic acids research 44 (10), e94-e94, 2016 | 38 | 2016 |
Toehold gene switches make big footprints S Ausländer, M Fussenegger Nature 516 (7531), 333-334, 2014 | 25 | 2014 |
Development and characterization of a monoclonal antibody against ochratoxin B and its application in ELISA AH Heussner, S Ausländer, DR Dietrich Toxins 2 (6), 1582-1594, 2010 | 15 | 2010 |