Systems biology of JAK-STAT signalling in human malignancies J Vera, K Rateitschak, F Lange, C Kossow, O Wolkenhauer, R Jaster Progress in biophysics and molecular biology 106 (2), 426-434, 2011 | 95 | 2011 |
AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro F Lange, K Weßlau, K Porath, MF Hörnschemeyer, C Bergner, BJ Krause, ... PLoS One 14 (2), e0211644, 2019 | 72 | 2019 |
Glutamatergic mechanisms in glioblastoma and tumor-associated epilepsy F Lange, J Hörnschemeyer, T Kirschstein Cells 10 (5), 1226, 2021 | 54 | 2021 |
Mathematical modelling of interferon-γ signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity K Rateitschak, A Karger, B Fitzner, F Lange, O Wolkenhauer, R Jaster Cellular signalling 22 (1), 97-105, 2010 | 52 | 2010 |
Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach F Lange, K Rateitschak, B Fitzner, R Pöhland, O Wolkenhauer, R Jaster Molecular cancer 10, 1-13, 2011 | 36 | 2011 |
Mitochondrial complex IV mutation increases reactive oxygen species production and reduces lifespan in aged mice G Reichart, J Mayer, C Zehm, T Kirschstein, T Tokay, F Lange, S Baltrusch, ... Acta Physiologica 225 (4), e13214, 2019 | 29 | 2019 |
Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells K Rateitschak, F Winter, F Lange, R Jaster, O Wolkenhauer PLoS computational biology 8 (12), e1002815, 2012 | 27 | 2012 |
Galectin-1 induced activation of the mitochondrial apoptotic pathway: evidence for a connection between death-receptor and mitochondrial pathways in human Jurkat T lymphocytes F Lange, B Brandt, M Tiedge, L Jonas, U Jeschke, R Pöhland, H Walzel Histochemistry and cell biology 132, 211-223, 2009 | 24 | 2009 |
Uncoupling protein 2 protects mice from aging M Hirose, P Schilf, F Lange, J Mayer, G Reichart, P Maity, O Jöhren, ... Mitochondrion 30, 42-50, 2016 | 23 | 2016 |
Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines F Lange, B Franz, C Maletzki, M Linnebacher, M Hühns, R Jaster BioMed Research International 2014, 2014 | 23 | 2014 |
Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach F Lange, K Rateitschak, C Kossow, O Wolkenhauer, R Jaster World journal of gastroenterology: WJG 18 (43), 6226, 2012 | 23 | 2012 |
Antifibrogenic effects of vitamin D derivatives on mouse pancreatic stellate cells P Wallbaum, S Rohde, L Ehlers, F Lange, A Hohn, C Bergner, ... World journal of gastroenterology 24 (2), 170, 2018 | 20 | 2018 |
Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice S Müller, H Kaiser, B Krüger, B Fitzner, F Lange, CN Bock, H Nizze, ... PLoS One 9 (4), e94494, 2014 | 17 | 2014 |
Distinct antifibrogenic effects of erlotinib, sunitinib and sorafenib on rat pancreatic stellate cells A Elsner, F Lange, B Fitzner, M Heuschkel, BJ Krause, R Jaster World journal of gastroenterology: WJG 20 (24), 7914, 2014 | 16 | 2014 |
Perampanel Add-on to Standard Radiochemotherapy in vivo Promotes Neuroprotection in a Rodent F98 Glioma Model F Lange, J Hartung, C Liebelt, J Boisserée, T Resch, K Porath, ... Frontiers in neuroscience 14, 598266, 2020 | 13 | 2020 |
Perampanel attenuates epileptiform phenotype in C6 glioma J Mayer, T Kirschstein, T Resch, K Porath, BJ Krause, R Köhling, F Lange Neuroscience Letters 715, 134629, 2020 | 13 | 2020 |
Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer S Rohde, T Lindner, S Polei, J Stenzel, L Borufka, S Achilles, E Hartmann, ... Oncotarget 8 (41), 69756, 2017 | 13 | 2017 |
Deciphering hallmark processes of aging from interaction networks S Smita, F Lange, O Wolkenhauer, R Koehling Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (11), 2706-2715, 2016 | 13 | 2016 |
Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines M Gock, CS Mullins, C Bergner, F Prall, R Ramer, A Göder, OH Krämer, ... World journal of gastroenterology 24 (43), 4880, 2018 | 10 | 2018 |
Galvanotactic migration of glioblastoma and brain metastases cells F Lange, J Venus, D Shams Esfand Abady, K Porath, A Einsle, ... Life 12 (4), 580, 2022 | 7 | 2022 |