Onur Dagliyan
Onur Dagliyan
Research Fellow, Harvard Medical School
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
Engineering extrinsic disorder to control protein activity in living cells
O Dagliyan, M Tarnawski, PH Chu, D Shirvanyants, I Schlichting, ...
Science 354 (6318), 1441-1444, 2016
1202016
Optimization based tumor classification from microarray gene expression data
O Dagliyan, F Uney-Yuksektepe, IH Kavakli, M Turkay
PloS one 6 (2), e14579, 2011
1022011
Structural and dynamic determinants of protein-peptide recognition
O Dagliyan, EA Proctor, KM D'Auria, F Ding, NV Dokholyan
Structure 19 (12), 1837-1845, 2011
882011
Rational design of a ligand-controlled protein conformational switch
O Dagliyan, D Shirvanyants, AV Karginov, F Ding, L Fee, ...
Proceedings of the National Academy of Sciences 110 (17), 6800-6804, 2013
842013
Knowledge-based design of a biosensor to quantify localized ERK activation in living cells
L Kummer, CW Hsu, O Dagliyan, C MacNevin, M Kaufholz, ...
Chemistry & biology 20 (6), 847-856, 2013
482013
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
PH Chu, D Tsygankov, ME Berginski, O Dagliyan, SM Gomez, TC Elston, ...
Proceedings of the National Academy of Sciences 111 (34), 12420-12425, 2014
402014
FRET binding antenna reports spatiotemporal dynamics of GDI–Cdc42 GTPase interactions
L Hodgson, D Spiering, M Sabouri-Ghomi, O Dagliyan, ...
Nature chemical biology 12 (10), 802-809, 2016
322016
Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC50 Using Common Molecular Descriptors
O Dagliyan, IH Kavakli, M Turkay
Journal of chemical information and modeling 49 (10), 2403-2411, 2009
272009
Computational approaches to understanding protein aggregation in neurodegeneration
RL Redler, D Shirvanyants, O Dagliyan, F Ding, DN Kim, P Kota, ...
Journal of molecular cell biology 6 (2), 104-115, 2014
252014
Intrinsic disorder mediates cooperative signal transduction in STIM1
Y Furukawa, S Teraguchi, T Ikegami, O Dagliyan, L Jin, D Hall, ...
Journal of molecular biology 426 (10), 2082-2097, 2014
242014
Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme
B Çakir, O Dağliyan, E Dağyildiz, İ Bariş, IH Kavakli, S Kizilel, M Türkay
PLoS One 7 (2), e31787, 2012
242012
Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity
TC Freeman Jr, JL Black, HG Bray, O Dagliyan, YI Wu, A Tripathy, ...
Biochemistry 52 (40), 7082-7090, 2013
212013
Computational design of chemogenetic and optogenetic split proteins
O Dagliyan, A Krokhotin, I Ozkan-Dagliyan, A Deiters, CJ Der, KM Hahn, ...
Nature communications 9 (1), 1-8, 2018
202018
Profiling cellular morphodynamics by spatiotemporal spectrum decomposition
X Ma, O Dagliyan, KM Hahn, G Danuser
PLoS computational biology 14 (8), e1006321, 2018
132018
Engineering Pak1 allosteric switches
O Dagliyan, AV Karginov, S Yagishita, ME Gale, H Wang, ...
ACS synthetic biology 6 (7), 1257-1262, 2017
132017
Gain-of-Function mutation W493R in the epithelial sodium channel allosterically reconfigures intersubunit coupling
M Shobair, O Dagliyan, P Kota, YL Dang, H He, MJ Stutts, NV Dokholyan
Journal of Biological Chemistry 291 (8), 3682-3692, 2016
112016
Engineering proteins for allosteric control by light or ligands
O Dagliyan, NV Dokholyan, KM Hahn
Nature protocols 14 (6), 1863, 2019
82019
Controlling protein conformation with light
O Dagliyan, KM Hahn
Current Opinion in Structural Biology 57, 17-22, 2019
72019
Morphodynamic Profiling of Cell Protrusion Based on Spatiotemporal Spectrum Decomposition and Unsupervised Clustering
X Ma, O Dagliyan, K Hahn, G Danuser
Biophysical Journal 112 (3), 45a, 2017
42017
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ...
Cell reports 31 (11), 107764, 2020
12020
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