Kei Sakamoto
Kei Sakamoto
University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ...
The Journal of clinical investigation 120 (7), 2355-2369, 2010
LKB1-dependent signaling pathways
DR Alessi, K Sakamoto, JR Bayascas
Annu. Rev. Biochem. 75, 137-163, 2006
The ancient drug salicylate directly activates AMP-activated protein kinase
SA Hawley, MD Fullerton, FA Ross, JD Schertzer, C Chevtzoff, KJ Walker, ...
Science 336 (6083), 918-922, 2012
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
EJ McManus, K Sakamoto, LJ Armit, L Ronaldson, N Shpiro, R Marquez, ...
The EMBO journal 24 (8), 1571-1583, 2005
AMPK: a key sensor of fuel and energy status in skeletal muscle
DG Hardie, K Sakamoto
Physiology 21 (1), 48-60, 2006
Anti-inflammatory effects of metformin irrespective of diabetes status
AR Cameron, VL Morrison, D Levin, M Mohan, C Forteath, C Beall, ...
Circulation research 119 (5), 652-665, 2016
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
K Sakamoto, A McCarthy, D Smith, KA Green, D Grahame Hardie, ...
The EMBO journal 24 (10), 1810-1820, 2005
Molecular mechanism of action of metformin: old or new insights?
G Rena, ER Pearson, K Sakamoto
Diabetologia 56, 1898-1906, 2013
Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
K Sakamoto, GD Holman
American journal of physiology-endocrinology and metabolism 295 (1), E29-E37, 2008
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase
O Göransson, A McBride, SA Hawley, FA Ross, N Shpiro, M Foretz, ...
Journal of Biological Chemistry 282 (45), 32549-32560, 2007
Important role of the LKB1-AMPK pathway in suppressing tumourigenesis in PTEN deficient mice
X Huang, S Wullschleger, N Shpiro, VA McGuire, K Sakamoto, YL Woods, ...
Biochemical Journal 412 (2), 211-221, 2010
How long does the protective effect on eccentric exercise-induced muscle damage last?
K Nosaka, KEI Sakamoto, M Newton, P Sacco
Medicine & Science in Sports & Exercise 33 (9), 1490-1495, 2001
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
R Mounier, M Théret, L Arnold, S Cuvellier, L Bultot, O Göransson, N Sanz, ...
Cell metabolism 18 (2), 251-264, 2013
Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells
FVN Din, A Valanciute, V Houde, D Zibrova, KA Green, K Sakamoto, ...
Gastroenterology, 2012
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study
A Sriwijitkamol, DK Coletta, E Wajcberg, GB Balbontin, SM Reyna, ...
Diabetes 56 (3), 836-848, 2007
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle
HF Kramer, CA Witczak, N Fujii, N Jessen, EB Taylor, DE Arnolds, ...
Diabetes 55 (7), 2067-2076, 2006
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR
K Sakamoto, O Goransson, DG Hardie, DR Alessi
American Journal of Physiology-Endocrinology and Metabolism 287 (2), E310-E317, 2004
Invited review: intracellular signaling in contracting skeletal muscle
K Sakamoto, LJ Goodyear
Journal of applied physiology 93 (1), 369-383, 2002
Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes
F Mauvais-Jarvis, K Ueki, DA Fruman, MF Hirshman, K Sakamoto, ...
The Journal of clinical investigation 109 (1), 141-149, 2002
Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function
EP Mottillo, EM Desjardins, JD Crane, BK Smith, AE Green, S Ducommun, ...
Cell metabolism 24 (1), 118-129, 2016
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