Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions F Palacios, JS Tushir, Y Fujita, C D'Souza-Schorey Molecular and cellular biology, 2005 | 408 | 2005 |
TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein S Bhatnagar, C Gazin, L Chamberlain, J Ou, X Zhu, JS Tushir, ... Nature 516 (7529), 116-120, 2014 | 163 | 2014 |
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons HP Shulha, JL Crisci, D Reshetov, JS Tushir, I Cheung, R Bharadwaj, ... PLoS biology 10 (11), e1001427, 2012 | 135 | 2012 |
A 5′-uridine amplifies miRNA/miRNA* asymmetry in Drosophilaby promoting RNA-induced silencing complex formation H Seitz, JS Tushir, PD Zamore Silence 2, 1-10, 2011 | 74 | 2011 |
ARF6‐dependent activation of ERK and Rac1 modulates epithelial tubule development JS Tushir, C D'Souza‐Schorey The EMBO journal 26 (7), 1806-1819, 2007 | 72 | 2007 |
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia R Bharadwaj, Y Jiang, W Mao, M Jakovcevski, A Dincer, W Krueger, ... Journal of Neuroscience 33 (29), 11839-11851, 2013 | 70 | 2013 |
Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice P Przanowski, U Wasko, Z Zheng, J Yu, R Sherman, LJ Zhu, ... Proceedings of the National Academy of Sciences 115 (31), 7991-7996, 2018 | 49 | 2018 |
Antibody-siRNA conjugates: drugging the undruggable for anti-leukemic therapy J Tushir-Singh Expert Opinion on Biological Therapy 17 (3), 325-338, 2017 | 37 | 2017 |
Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis JS Tushir, J Clancy, A Warren, C Wrobel, JS Brugge, C D'Souza-Schorey Molecular biology of the cell 21 (13), 2355-2366, 2010 | 36 | 2010 |
A single-agent dual-specificity targeting of FOLR1 and DR5 as an effective strategy for ovarian cancer G Shivange, K Urbanek, P Przanowski, JSA Perry, J Jones, R Haggart, ... Cancer cell 34 (2), 331-345. e11, 2018 | 34 | 2018 |
SnapShot: Fly piRNAs, PIWI proteins, and the ping-pong cycle JS Tushir, PD Zamore, Z Zhang Cell 139 (3), 634-634. e1, 2009 | 30 | 2009 |
Oncogenic TRIM37 links chemoresistance and metastatic fate in triple-negative breast cancer P Przanowski, S Lou, RD Tihagam, T Mondal, C Conlan, G Shivange, ... Cancer research 80 (21), 4791-4804, 2020 | 18 | 2020 |
Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies T Mondal, GN Shivange, RGT Tihagam, E Lyerly, M Battista, D Talwar, ... EMBO molecular medicine 13 (3), e12716, 2021 | 13 | 2021 |
Bispecific antibodies for the treatment of breast cancer PM Dillon, J Tushir-Singh, LG Lum Expert opinion on biological therapy 22 (8), 1017-1027, 2022 | 12 | 2022 |
Chromatin-bound RNA and the neurobiology of psychiatric disease JS Tushir, S Akbarian Neuroscience 264, 131-141, 2014 | 11 | 2014 |
A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors G Shivange, T Mondal, E Lyerly, S Bhatnagar, CN Landen, S Reddy, ... Cell reports 37 (5), 2021 | 5 | 2021 |
Arming “old guards” with “new dual-targeting weapons” LG Lum, J Tushir-Singh Cancer Cell 39 (5), 604-606, 2021 | 4 | 2021 |
Triple-negative breast cancer M Huang, J O'Shaughnessy, J Zhao, A Haiderali, J Cortés, SD Ramsey, ... | 4 | 2021 |
In vitro assay to study histone ubiquitination during transcriptional regulation J Tushir-Singh, S Bhatnagar Eukaryotic Transcriptional and Post-Transcriptional Gene Expression …, 2017 | 4 | 2017 |
Characterizing the regulatory Fas (CD95) epitope critical for agonist antibody targeting and CAR-T bystander function in ovarian cancer T Mondal, H Gaur, BEN Wamba, AG Michalak, C Stout, MR Watson, ... Cell Death & Differentiation 30 (11), 2408-2431, 2023 | 1 | 2023 |