| Activating ESR1 mutations in hormone-resistant metastatic breast cancer DR Robinson, YM Wu, P Vats, F Su, RJ Lonigro, X Cao, ... Nature genetics 45 (12), 1446-1451, 2013 | 1177 | 2013 |
| CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment Y Jin, Z Desta, V Stearns, B Ward, H Ho, KH Lee, T Skaar, AM Storniolo, ... Journal of the National Cancer Institute 97 (1), 30-39, 2005 | 1175 | 2005 |
| Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine V Stearns, MD Johnson, JM Rae, A Morocho, A Novielli, P Bhargava, ... Journal of the National Cancer Institute 95 (23), 1758-1764, 2003 | 1034 | 2003 |
| Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes MP Goetz, JM Rae, VJ Suman, SL Safgren, MM Ames, DW Visscher, ... Journal of Clinical Oncology 23 (36), 9312-9318, 2005 | 982 | 2005 |
| The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen MP Goetz, SK Knox, VJ Suman, JM Rae, SL Safgren, MM Ames, ... Breast cancer research and treatment 101, 113-121, 2007 | 691 | 2007 |
| Pharmacological Characterization of 4-hydroxy-N-desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen MD Johnson, H Zuo, KH Lee, JP Trebley, JM Rae, RV Weatherman, ... Breast cancer research and treatment 85, 151-159, 2004 | 573 | 2004 |
| MDA-MB-435 cells are derived from M14 Melanoma cells––a loss for breast cancer, but a boon for melanoma research JM Rae, CJ Creighton, JM Meck, BR Haddad, MD Johnson Breast cancer research and treatment 104, 13-19, 2007 | 442 | 2007 |
| Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays JM Rae, MD Johnson, ME Lippman, DA Flockhart Journal of Pharmacology and Experimental Therapeutics 299 (3), 849-857, 2001 | 411 | 2001 |
| CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women with Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial MM Regan, B Leyland-Jones, M Bouzyk, O Pagani, W Tang, R Kammler, ... Journal of the National Cancer Institute 104 (6), 441-451, 2012 | 384 | 2012 |
| Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients SA Nowell, J Ahn, JM Rae, JO Scheys, A Trovato, C Sweeney, ... Breast cancer research and treatment 91, 249-258, 2005 | 355 | 2005 |
| GREB1 is a critical regulator of hormone dependent breast cancer growth JM Rae, MD Johnson, JO Scheys, KE Cordero, JM Larios, ME Lippman Breast cancer research and treatment 92, 141-149, 2005 | 307 | 2005 |
| Activation of mitogen-activated protein kinase in estrogen receptor α–positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor α … CJ Creighton, AM Hilger, S Murthy, JM Rae, AM Chinnaiyan, D El-Ashry Cancer research 66 (7), 3903-3911, 2006 | 306 | 2006 |
| CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients JM Rae, S Drury, DF Hayes, V Stearns, JN Thibert, BP Haynes, J Salter, ... Journal of the National Cancer Institute 104 (6), 452-460, 2012 | 303 | 2012 |
| The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression YS Niknafs, S Han, T Ma, C Speers, C Zhang, K Wilder-Romans, MK Iyer, ... Nature communications 7 (1), 12791, 2016 | 207 | 2016 |
| Comparative analysis of circulating tumor DNA stability In K3EDTA, Streck, and CellSave blood collection tubes Q Kang, NL Henry, C Paoletti, H Jiang, P Vats, AM Chinnaiyan, DF Hayes, ... Clinical biochemistry 49 (18), 1354-1360, 2016 | 201 | 2016 |
| (−)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer L Xu, D Yang, S Wang, W Tang, M Liu, M Davis, J Chen, JM Rae, ... Molecular cancer therapeutics 4 (2), 197-205, 2005 | 201 | 2005 |
| Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells YC Lim, L Li, Z Desta, Q Zhao, JM Rae, DA Flockhart, TC Skaar Journal of Pharmacology and Experimental Therapeutics 318 (2), 503-512, 2006 | 184 | 2006 |
| ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients D Chu, C Paoletti, C Gersch, DA VanDenBerg, DJ Zabransky, ... Clinical cancer research 22 (4), 993-999, 2016 | 183 | 2016 |
| Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivoin tumor xenografts and human breast tumors CJ Creighton, KE Cordero, JM Larios, RS Miller, MD Johnson, ... Genome biology 7, 1-13, 2006 | 156 | 2006 |
| Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism JM Rae, NV Soukhova, DA Flockhart, Z Desta Drug Metabolism and Disposition 30 (5), 525-530, 2002 | 136 | 2002 |
