TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling P Bragado, Y Estrada, F Parikh, S Krause, C Capobianco, HG Farina, ... Nature cell biology 15 (11), 1351-1361, 2013 | 486 | 2013 |
NR2F1 controls tumour cell dormancy via SOX9-and RARβ-driven quiescence programmes MS Sosa, F Parikh, AG Maia, Y Estrada, A Bosch, P Bragado, E Ekpin, ... Nature communications 6 (1), 6170, 2015 | 299 | 2015 |
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release P Jayaraman, F Parikh, E Lopez-Rivera, Y Hailemichael, A Clark, G Ma, ... The Journal of Immunology 188 (11), 5365-5376, 2012 | 184 | 2012 |
Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2 E Lopez-Rivera, P Jayaraman, F Parikh, MA Davies, S Ekmekcioglu, ... Cancer research 74 (4), 1067-1078, 2014 | 110 | 2014 |
Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer F Parikh, D Duluc, N Imai, A Clark, K Misiukiewicz, M Bonomi, V Gupta, ... Cancer research 74 (24), 7205-7216, 2014 | 104 | 2014 |
Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8+ T Cells in Head and Neck Cancer S Krishna, P Ulrich, E Wilson, F Parikh, P Narang, S Yang, AK Read, ... Cancer research 78 (21), 6159-6170, 2018 | 75 | 2018 |
Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy A Hanoteau, JM Newton, R Krupar, C Huang, HC Liu, A Gaspero, ... Journal for immunotherapy of cancer 7, 1-19, 2019 | 72 | 2019 |
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition JM Newton, A Hanoteau, HC Liu, A Gaspero, F Parikh, ... Journal for immunotherapy of cancer 7, 1-21, 2019 | 70 | 2019 |
iNOS Expression in CD4+ T Cells Limits Treg Induction by Repressing TGFβ1: Combined iNOS Inhibition and Treg Depletion Unmask Endogenous Antitumor … P Jayaraman, MG Alfarano, PF Svider, F Parikh, G Lu, S Kidwai, H Xiong, ... Clinical cancer research 20 (24), 6439-6451, 2014 | 66 | 2014 |
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with … P Jayaraman, F Parikh, JM Newton, A Hanoteau, C Rivas, R Krupar, ... Oncoimmunology 7 (10), e1490853, 2018 | 56 | 2018 |
Therapeutic HPV Cancer Vaccine Targeted to CD40 Elicits Effective CD8+ T-cell Immunity W Yin, D Duluc, HM Joo, Y Xue, C Gu, Z Wang, L Wang, R Ouedraogo, ... Cancer immunology research 4 (10), 823-834, 2016 | 27 | 2016 |
Abstract LB-095: HPV E7 antigen-expressing Listeria-based immunotherapy (ADXS11-001) prior to robotic surgery for HPV-positive oropharyngeal cancer enhances HPV-specific T cell … R Krupar, N Imai, B Miles, E Genden, K Misiukiewicz, Y Saenger, ... Cancer Research 76 (14_Supplement), LB-095-LB-095, 2016 | 19 | 2016 |
Changes in local and peripheral T cell diversity after HPV E7 antigen-expressing Listeria-based immunotherapy (ADXS11-001) prior to robotic surgery for HPV-positive … R Krupar, RR Pathak, N Imai, E Genden, K Misiukiewicz, EG Demicco, ... Cancer Research 78 (13_Supplement), 5639-5639, 2018 | 1 | 2018 |
HPV E7 antigen-expressing Listeria-based immunotherapy (ADXS11-001) prior to robotic surgery for HPV-positive oropharyngeal cancer enhances HPV-specific T cell immunity … R Krupar, N Imai, B Miles, E Genden, K Misiukiewicz, Y Saenger, ... Cancer Res 76 (14 Suppl), 2016 | 1 | 2016 |
Abstract PR005: TGF-beta1 primed myeloid derived suppressor cells decrease tumor growth and lose their ability to inhibit T cell proliferation via iNOS downregulation P Jayaraman, F Parikh, R Krupar, R Parihar, I Varier, A Sikora Cancer Immunology Research 4 (1_Supplement), PR005-PR005, 2016 | 1 | 2016 |
Immune stimulatory function and anti-tumor activity of TGF-β primed myeloid derived suppressor cells (MDSC) A Sikora, P Jayaraman, F Parikh, R Parihar US Patent 11,090,333, 2021 | | 2021 |
Radiation, immune checkpoint inhibition, and modulation of the tumor immune microenvironment promotes immunologic rejection of established HPV-associated tumors JM Newton, A Hanoteau, HC Liu, A Gaspero, RD Gartrell, TD Hart, ... Cancer Research 79 (13_Supplement), 4068-4068, 2019 | | 2019 |
Concurrent in vitro and in silico approach for the identification of surface proteome targets on HPV-associated cancer cells HC Liu, I Carrero, F Parikh, T Kraus, TM Moran, MJ Ellis, EY Chiao, ... Cancer Research 79 (13_Supplement), 2124-2124, 2019 | | 2019 |
Novel T-cell targets for HPV16-associated oropharyngeal cancer immune therapy S Krishna, F Parikh, P Ulrich, S Yang, A Clark, S Kim-Schulze, M Posner, ... Cancer Research 77 (13_Supplement), 4559-4559, 2017 | | 2017 |
Characterization of monoclonal antibodies specific for HPV-positive head and neck cancer HC Liu, F Parikh, T Kraus, T Moran, A Sikora Cancer Research 77 (13_Supplement), 2211-2211, 2017 | | 2017 |