Lesley Mathews
Lesley Mathews
Verified email at novartis.com
Title
Cited by
Cited by
Year
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
Y Yang, AL Shaffer III, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer cell 21 (6), 723-737, 2012
4312012
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with …
MM Mita, AC Mita, QS Chu, EK Rowinsky, GJ Fetterly, M Goldston, ...
Journal of Clinical Oncology 26 (3), 361-367, 2008
2922008
Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature
GJ Klarmann, EM Hurt, LA Mathews, X Zhang, MA Duhagon, T Mistree, ...
Clinical & experimental metastasis 26 (5), 433-446, 2009
2332009
The cancer stem cell niche—there goes the neighborhood?
SM Cabarcas, LA Mathews, WL Farrar
International Journal of Cancer 129 (10), 2315-2327, 2011
2262011
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer
F Crea, EM Hurt, LA Mathews, SM Cabarcas, L Sun, VE Marquez, ...
Molecular cancer 10 (1), 40, 2011
1652011
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome
GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ...
Cancer cell 24 (1), 90-104, 2013
1402013
Epigenetic regulation of SOX9 by the NF‐κB signaling pathway in pancreatic cancer stem cells
L Sun, LA Mathews, SM Cabarcas, X Zhang, A Yang, Y Zhang, MR Young, ...
Stem cells 31 (8), 1454-1466, 2013
1022013
Epigenetic gene regulation in stem cells and correlation to cancer
LA Mathews, F Crea, WL Farrar
Differentiation 78 (1), 1-17, 2009
842009
Increased expression of DNA repair genes in invasive human pancreatic cancer cells
LA Mathews, SM Cabarcas, EM Hurt, X Zhang, EM Jaffee, WL Farrar
Pancreas 40 (5), 730, 2011
682011
DNA repair: the culprit for tumor-initiating cell survival?
LA Mathews, SM Cabarcas, WL Farrar
Cancer and metastasis reviews 30 (2), 185-197, 2011
442011
Estrogen and progesterone regulate radiation-induced p53 activity in mammary epithelium through TGF-β-dependent pathways
KA Becker, S Lu, ES Dickinson, KA Dunphy, L Mathews, SS Schneider, ...
Oncogene 24 (42), 6345-6353, 2005
432005
Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins
L Casson, L Howell, LA Mathews, M Ferrer, N Southall, R Guha, JM Keller, ...
PLoS One 8 (1), e54525, 2013
382013
Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells
LA Mathews, EM Hurt, X Zhang, WL Farrar
Molecular cancer 9 (1), 267, 2010
372010
Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity
S Lu, KA Becker, MJ Hagen, H Yan, AL Roberts, LA Mathews, ...
Endocrinology 149 (10), 4809-4820, 2008
372008
A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells
LA Mathews, JM Keller, BL Goodwin, R Guha, P Shinn, R Mull, ...
Journal of biomolecular screening 17 (9), 1231-1242, 2012
322012
Targeting prostate cancer stem cells
F Crea, LA Mathews, WL Farrar, EM Hurt
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009
292009
DNA repair of cancer stem cells
LA Mathews, SM Cabarcas, EM Hurt
Springer, 2013
232013
Inhibitory effects of Hedyotis diffusa Willd. on colorectal cancer stem cells
G Sun, L Wei, J Feng, J Lin, J Peng
Oncology letters 11 (6), 3875-3881, 2016
212016
Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression
Y Zhang, SM Cabarcas, JI Zheng, L Sun, LA Mathews, X Zhang, H Lin, ...
Oncology Letters 11 (6), 3803-3812, 2016
102016
Multiplexing High‐Content Flow (HCF) and Quantitative High‐Throughput Screening (qHTS) to Identify Compounds Capable of Decreasing Cell Viability, Activating Caspase 3/7 …
LA Mathews, JM Keller, C McKnight, S Michael, P Shinn, D Liu, LM Staudt, ...
Current protocols in chemical biology 5 (3), 195-212, 2013
62013
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